{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T06:00:31Z","timestamp":1740808831782,"version":"3.38.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1995,2,1]],"date-time":"1995-02-01T00:00:00Z","timestamp":791596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovascular Surgery"],"published-print":{"date-parts":[[1995,2]]},"abstract":"<jats:p> An increased incidence of premature atherosclerotic arterial occlusive disease was recently reported in young adults. This condition is characterized by early occurrence of severe symptoms, lower incidence of typical cardiovascular risk factors for atherosclerosis, different natural course of arterial disease vis-a-vis older population, and poor outcome of a standard treatment. This report describes a young man with aggressive arterial occlusive disease in the lower extremities and symptom-free occlusions of coronary and renal arteries in association with high levels of lipoprotein(a). Microscopic early atherosclerotic changes were noted in the occluded arteries of the amputated leg. Premature atherosclerotic arterial occlusive disease in young adults has different clinical and pathological patterns, necessitating a different approach for evaluation and treatment. <\/jats:p>","DOI":"10.1177\/096721099500300111","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T17:04:14Z","timestamp":1727111054000},"page":"56-59","source":"Crossref","is-referenced-by-count":0,"title":["Diffuse Arterial Thrombosis in a Young Man with Elevated Lipoprotein(a) and Minimal Atherosclerosis"],"prefix":"10.1177","volume":"3","author":[{"given":"P. J.","family":"Levy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of South Carolina, Richland Memorial Hospital. Columbia, South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Sheridant","sequence":"additional","affiliation":[{"name":"Department of Invasive Radiology. University of South Carolina, Richland Memorial Hospital. Columbia, South Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Carter","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Lexington Medical Center. Lexington. South Carolina. USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. L.","family":"Haynes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1995,2,1]]},"reference":[{"key":"bibr1-096721099500300111","first-page":"647","volume":"202","author":"Hallet JW","year":"1985","journal-title":"Lower extremity arterial disease in young adults: A systematic approach to early diagnosis"},{"key":"bibr2-096721099500300111","first-page":"560","volume":"107","author":"Valentine RJ","year":"1990","journal-title":"Intermittent claudication caused by atherosclerosis in patients aged 20 years and younger"},{"key":"bibr3-096721099500300111","doi-asserted-by":"crossref","unstructured":"Levy PJ, Hornung CA, Rush DS, Davis DW, Haynes JL. Lower extremity ischemia in adults less than 40 years of age: A community-wide survey of premature atherosclerotic arterial disease. J Vasc Surg 1994 (in press).","DOI":"10.1016\/S0741-5214(94)70013-3"},{"key":"bibr4-096721099500300111","first-page":"775","volume":"88","author":"Cronenwett JL","year":"1980","journal-title":"Aortoiliac occlusive disease in women"},{"key":"bibr5-096721099500300111","first-page":"334","volume":"9","author":"Eldrup-Jorgensen EJ","year":"1989","journal-title":"Hypercoagulable states and lower limb ischemia in young adults"},{"key":"bibr6-096721099500300111","first-page":"1109","volume":"70","author":"Mouratidis B","year":"1992","journal-title":"Detection of silent coronary artery disease in adolescents and young adults with familial hypercholesterolemia by single-photon emission computed tomography Thallium-201 scanning."},{"key":"bibr7-096721099500300111","first-page":"851","volume":"70","author":"Berenson GS","year":"1992","journal-title":"Atherosclerosis of the aorta and coronary arteries and cardiovascular risk factors in persons aged 6 to 30 years and studied at necropsy (Bogalusa Heart Study)"},{"key":"bibr8-096721099500300111","first-page":"1028","volume":"140","author":"Asherson RA","year":"1988","journal-title":"Renal infarction in systemic lupus erythematosus"},{"key":"bibr9-096721099500300111","first-page":"184","volume":"49","author":"Ostrini PA","year":"1990","journal-title":"Renal artery thrombosis and hypertension in 13-year old girl with antiphospholipid syndrome"},{"key":"bibr10-096721099500300111","first-page":"1802","volume":"19","author":"Ames PRJ","year":"1992","journal-title":"Bilateral renal artery occlusion in a patient with primary antiphospholipid antibody syndrome: Thrombosis, vasculitis, or both?"},{"key":"bibr11-096721099500300111","first-page":"500","volume":"20","author":"Mandreoli M","year":"1992","journal-title":"Fibromuscular dysplasia of the renal arteries associated with antiphospholipid autoantibodies: Two case reports"},{"key":"bibr12-096721099500300111","first-page":"13","volume":"63","author":"Johnson EJ","year":"1990","journal-title":"Premature arterial disease associated with familial antithrombin III deficiency"},{"key":"bibr13-096721099500300111","first-page":"180","volume":"14","author":"Collen D","year":"1988","journal-title":"Fibrinolysis and atherosclerosis"},{"key":"bibr14-096721099500300111","first-page":"3326","volume":"267","author":"Scanu AM","year":"1992","journal-title":"Lipoprotein(a). A genetic risk factor for premature coronary heart disease"},{"key":"bibr15-096721099500300111","first-page":"303","volume":"339","author":"Najjar KA","year":"1989","journal-title":"Lipoprotein(a) modulation of endothelial cell surface fibrinolysis and its potential role in atherosclerosis"},{"key":"bibr16-096721099500300111","first-page":"333","volume":"303","author":"Om A","year":"1992","journal-title":"Cardiovascular complications of cocaine"}],"container-title":["Cardiovascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096721099500300111","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/096721099500300111","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T23:02:04Z","timestamp":1740783724000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/096721099500300111"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,2]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1995,2]]}},"alternative-id":["10.1177\/096721099500300111"],"URL":"https:\/\/doi.org\/10.1177\/096721099500300111","relation":{},"ISSN":["0967-2109"],"issn-type":[{"type":"print","value":"0967-2109"}],"subject":[],"published":{"date-parts":[[1995,2]]}}}