{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T10:24:34Z","timestamp":1778754274485,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1998,6,1]],"date-time":"1998-06-01T00:00:00Z","timestamp":896659200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiovascular Surgery"],"published-print":{"date-parts":[[1998,6]]},"abstract":"<jats:p> Paradoxical emboli are considered a rare event, representing less than 2% of all arterial emboli. The most common intracardiac defect associated with paradoxical emboli is a patent foramen ovale. Most commonly, a pulmonary embolism is the cause of the acute increase in right atrial pressure leading to a reversal of intracardiac flow and passage of venous embolic material to the left heart. We present a patient with a pulmonary embolism and paradoxical emboli, and discuss therapeutic approach. We suggest that the treatment of choice for the patient with pulmonary embolism and non-limb-threatening acute ischemia due to a paradoxical emboli should be thrombolytic therapy and intracaval filter placement, followed by patent foramen ovale repair. <\/jats:p>","DOI":"10.1177\/096721099800600314","type":"journal-article","created":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T08:27:00Z","timestamp":1727166420000},"page":"302-306","source":"Crossref","is-referenced-by-count":6,"title":["The Role of Thrombolytic Therapy in the Management of Paradoxical Embolism"],"prefix":"10.1177","volume":"6","author":[{"given":"A.","family":"d'Audiffret","sequence":"first","affiliation":[{"name":"Department of Surgery, SUNY at Buffalo, Buffalo, New York, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. S.","family":"Shenoy","sequence":"additional","affiliation":[{"name":"Department of Radiology, Millard Fillmore Hospital, Buffalo, New York 14209, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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