{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:44:29Z","timestamp":1777855469151,"version":"3.51.4"},"reference-count":85,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2013,7,4]],"date-time":"2013-07-04T00:00:00Z","timestamp":1372896000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Biogr"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:p>Thomas Paytherus was born in Fownhope and apprenticed in Gloucester. He practised there and in Ross-on-Wye where he and Edward Jenner undertook an autopsy on a patient with angina that they linked causally to coronary artery ossification. In 1794 Paytherus moved to London and opened a highly successful pharmacy that he later sold to his partners Savory and Moore. Paytherus was among those who advised Jenner on the publication of his work on vaccination. Then he acted as an intermediary in the dispute between Jenner and Ingen-Housz and also alerted Jenner to Pearson\u2019s claims as a pioneer of vaccination. In 1800 he published a detailed analysis of the dispute between Jenner and Woodville whose patients had developed variola-like lesions following vaccination. Their correspondence shows that Paytherus, Jenner and their families remained firm friends. Paytherus and his family moved to Abergavenny where he died in 1828.<\/jats:p>","DOI":"10.1177\/0967772013479285","type":"journal-article","created":{"date-parts":[[2013,7,4]],"date-time":"2013-07-04T22:05:07Z","timestamp":1372975507000},"page":"169-179","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Thomas Paytherus (1752\u20131828): Entrepreneurial surgeon-apothecary and ardent Jennerian"],"prefix":"10.1177","volume":"21","author":[{"given":"Henry","family":"Connor","sequence":"first","affiliation":[{"name":"Vineyard Road Hereford, HR1 1TT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M","family":"Clark","sequence":"additional","affiliation":[{"name":"Independent Historical Geographer, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,7,4]]},"reference":[{"key":"bibr1-0967772013479285","unstructured":"Hereford Record Office: Parish Registers AC18\/1-3; Vestry Accounts AC18\/17; Paytherus family deeds A9."},{"key":"bibr2-0967772013479285","unstructured":"Wallis PJ, Wallis RV. Eighteenth century medics: subscriptions, licences, apprenticeships, Newcastle upon Tyne: Project for Historical Biography, 1988, pp. 112, 457\u2013458."},{"key":"bibr3-0967772013479285","unstructured":"Hereford Record Office T99\/11\/72."},{"key":"bibr4-0967772013479285","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1136\/bmj.2.3904.854","volume":"2","author":"Wall C","year":"1935","journal-title":"British Medical Journal"},{"key":"bibr5-0967772013479285","unstructured":"Whitcombe G.\n                      The General Infirmary at Gloucester and the Gloucestershire Eye Institution: its past and present\n                      . Gloucester: [sn], 1903, pp.88\u201389."},{"key":"bibr6-0967772013479285","unstructured":"Garlick K and Macintyre A, eds.\n                      The diary of Joseph Farington\n                      . New Haven: Yale University Press, 1984, vol. III pp.661, 664\u2013665."},{"key":"bibr7-0967772013479285","unstructured":"Bevan M.\n                      Henry Cline (1750\u20131827), Oxford Dictionary of National Biography.\n                      Oxford University Press, on-line edition, http:\/\/www.oxforddnb.com\/view\/article\/5673 (2004, accessed 27 September 2010)."},{"key":"bibr8-0967772013479285","unstructured":"Cooper BB. Life of Sir Astley Cooper, Bart 1843; Vol. 1, London: John W Parker, pp. 95\u201396."},{"key":"bibr9-0967772013479285","unstructured":"Doyle WP.\n                      Joseph Black (1728\u20131799)\n                      . School of Chemistry, University of Edinburgh, http:\/\/www.chem.ed.ac.uk\/about\/professors\/black.html (accessed 28 September 2010)."},{"key":"bibr10-0967772013479285","unstructured":"Laws and List of the Members of the Royal Medical Society of Edinburgh\n                      . 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Almeley, Logaston Press, 1999 pp.27\u201329."},{"key":"bibr17-0967772013479285","unstructured":"Sun Fire insurance Policy. Guildhall Library, London entry 466709, p.139. The house was described as new, of brick and stone not exceeding \u00a3200 in value and with household goods also not exceeding \u00a3200."},{"key":"bibr18-0967772013479285","unstructured":"Hereford Journal\n                      24 July 1788 p.3 column 2; 27 Aug 1794 p.3 column 4; 17 Sept 1794 p.3 column 2."},{"key":"bibr19-0967772013479285","unstructured":"Taylor E. Kings Caple in Archenfield, Almeley: Logaston Press, 1997, pp. 272\u2013273."},{"key":"bibr20-0967772013479285","unstructured":"Grundy I. Montagu, Lady Mary Wortley (\n                      bap.\n                      1689,\n                      d.\n                      1762).\n                      Oxford Dictionary of National Biography.\n                      Oxford University Press, http:\/\/www.oxforddnb.com\/view\/article\/19029 (2004, accessed 4 July 2011)."},{"key":"bibr21-0967772013479285","doi-asserted-by":"publisher","DOI":"10.1258\/j.jmb.2005.04-15"},{"key":"bibr22-0967772013479285","unstructured":"Royal College of Physicians of London. Regulations and Transactions of the Gloucestershire Medical Society. MS_GLOUM\/736."},{"key":"bibr23-0967772013479285","unstructured":"Parry CH. An inquiry into the symptoms and causes of the syncope anginosa, commonly called Angina pectoris, Bath: Crutwell, 1799, pp. 2\u201313."},{"key":"bibr24-0967772013479285","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.46.6.589"},{"key":"bibr25-0967772013479285","unstructured":"List of graduates in medicine in the University of Edinburgh from 1705 to 1806\n                      . Edinburgh: University of Edinburgh, 1867."},{"key":"bibr26-0967772013479285","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.50.3.209"},{"key":"bibr27-0967772013479285","unstructured":"House of Lords.\n                      The Sessional Papers 1801\u20131833\n                      , volume 46 B 1810-11:811-2."},{"key":"bibr28-0967772013479285","first-page":"219","volume":"231","author":"Matthews LG","year":"1983","journal-title":"The Pharmaceutical Journal"},{"key":"bibr29-0967772013479285","unstructured":"Fisher RB.\n                      Edward Jenner 1749\u20131823\n                      . London: Andr\u00e9 Deutsch, 1991, pp.69, 71, 75, 88\u201389,155, 174\u2013175, 262, 288."},{"key":"bibr30-0967772013479285","unstructured":"The Times\n                      5 November 1795 p.1 column 3."},{"key":"bibr31-0967772013479285","unstructured":"Richmond L, Stevenson J, Turton A. The pharmaceutical industry: a guide to historical records, Aldershot: Ashgate, 2003, pp. 4, 308\u2013311."},{"key":"bibr32-0967772013479285","first-page":"1177","volume":"9","author":"Reece R","year":"1824","journal-title":"Monthly Gazette of Health"},{"key":"bibr33-0967772013479285","unstructured":"Anon. How to enjoy social life.\n                      Literary Gazette\n                      , 24 June 1848, p.423."},{"key":"bibr34-0967772013479285","first-page":"1005","volume":"25","author":"Whitebread C","year":"1936","journal-title":"Journal of the American Pharmaceutical Association"},{"key":"bibr35-0967772013479285","unstructured":"Anon.\n                      A companion to the medicine chest\n                      . London: J Tindal, 1804, 55pp."},{"key":"bibr36-0967772013479285","volume-title":"A companion to the medicine chest","author":"Savory J","year":"1836"},{"key":"bibr37-0967772013479285","unstructured":"Hardwick M. Emma, Lady Hamilton, London: Cassell, 1969, pp. 155\u2013156."},{"key":"bibr38-0967772013479285","unstructured":"Hemlow J, Douglas A, Hawkins P, eds.\n                      The Journals and Letters of Fanny Burney (Madame D\u2019Arblay),\n                      Vol. XI, Mayfair 1818\u20131824. Oxford: Clarendon Press, 1984, p.400."},{"key":"bibr39-0967772013479285","unstructured":"Anon. Obituary. Thomas Field Savory.\n                      Freemasons Quarterly Review\n                      , 1847; 14: 334."},{"key":"bibr40-0967772013479285","unstructured":"Anon. Savory and Moore to end 184 years in Bond Street.\n                      Pharmaceutical Journal\n                      1981; 226: 172."},{"key":"bibr41-0967772013479285","unstructured":"Boyle\u2019s new fashionable court and country guide; and town visiting directory for 1798\n                      . London: Eliza Boyle and Son, 1798, p.66."},{"key":"bibr42-0967772013479285","unstructured":"Baron J.\n                      The life of Edward Jenner, M.D\n                      . 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George Man Burrows (1771\u20131846).\n                      Oxford Dictionary of National Biography.\n                      Oxford University Press, http:\/\/www.oxforddnb.com\/view\/article\/4114 (2004, accessed 19 February 2011)."},{"key":"bibr49-0967772013479285","doi-asserted-by":"crossref","unstructured":"Smith JR. Jesty, Benjamin (\n                      bap.\n                      1736,\n                      d.\n                      1816).\n                      Oxford Dictionary of National Biography\n                      , Oxford University Press, http:\/\/www.oxforddnb.com\/view\/article\/37605 (2004, accessed 4 July 2011).","DOI":"10.1093\/ref:odnb\/37605"},{"key":"bibr50-0967772013479285","unstructured":"Darwin F. Francis Galton 1822\u20131911.\n                      The Eugenics Review\n                      1915; 6: 1\u201317."},{"key":"bibr51-0967772013479285","unstructured":"Rogers WR. An examination of that part of the evidence relative to cow-pox, which was delivered to the Committee of the House of Commons by two of the Surgeons of St. Thomas\u2019s Hospital, 2nd edn. London: J Callow, 1805, pp. 9\u201310."},{"key":"bibr52-0967772013479285","doi-asserted-by":"publisher","DOI":"10.1093\/jhmas\/XII.10.449"},{"key":"bibr53-0967772013479285","unstructured":"Untitled.\n                      Hereford Journal\n                      9 May 1810 p.3 column 5."},{"key":"bibr54-0967772013479285","unstructured":"Cow Pox.\n                      Hereford Journal\n                      10 Feb 1802 p.2 column 4."},{"key":"bibr55-0967772013479285","doi-asserted-by":"publisher","DOI":"10.1017\/S0025727300064747"},{"key":"bibr56-0967772013479285","unstructured":"Jenner E. An inquiry into the causes and effects of the variolae vaccinae, London: Sampson Low, 1798, pp. 75\u201375."},{"key":"bibr57-0967772013479285","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-695X.1996.tb00105.x"},{"key":"bibr58-0967772013479285","unstructured":"Saunders P. Edward Jenner, the Cheltenham years, 1795\u20131823, London: University Press of New England, 1982, pp. 57\u201357."},{"key":"bibr59-0967772013479285","unstructured":"Le Fanu WR. A bio-bibliography of Edward Jenner, 1749\u20131823, London: Harvey and Blythe, 1951, pp. 24\u201324."},{"key":"bibr60-0967772013479285","doi-asserted-by":"crossref","unstructured":"Ingen Housz JM, Beale, N and Beale E. The life of Dr Jan Ingen Housz (1730\u201399), private counsellor and personal physician to Emperor Joseph II of Austria.\n                      Journal of Medical Biography\n                      2005; 13: 15\u201321.","DOI":"10.1177\/096777200501300106"},{"key":"bibr61-0967772013479285","first-page":"202","volume":"51","author":"van der Pas PW","year":"1964","journal-title":"Janus"},{"key":"bibr62-0967772013479285","doi-asserted-by":"publisher","DOI":"10.1017\/S0025727300008292"},{"key":"bibr63-0967772013479285","unstructured":"The Monthly Magazine or British Register\n                      . 1800; 10: 1. This testimonial appeared in many other periodicals, both medical and lay."},{"key":"bibr64-0967772013479285","unstructured":"Baxby D. Jenner\u2019s smallpox vaccine, London: Heinemann Educational Books, 1981, pp. 147\u2013148."},{"key":"bibr65-0967772013479285","unstructured":"Anon. A Comparative statement of facts and observations relative to the cow-pox; published by Drs Jenner and Woodville, London: Sampson Low, 1800, pp. 43\u201343."},{"key":"bibr66-0967772013479285","unstructured":"Ring J. A treatise on the cow-pox, containing the history of vaccine inoculation. Part II, London: Carpenter and Johnson, 1803, pp. 636, 832\u2013636, 832."},{"key":"bibr67-0967772013479285","unstructured":"Royal Jennerian Society for the Extermination of the Small-pox.\n                      Edinburgh Medical and Surgical Journal\n                      1806; 2: 254\u2013257."},{"key":"bibr68-0967772013479285","unstructured":"Medical Society of London Archive\n                      , Wellcome Institute. SA\/MSL\/A\/1\/1; SA\/MSL\/D\/2\/1\/3."},{"key":"bibr69-0967772013479285","unstructured":"Le Fanu W. A Bibliography of Edward Jenner, Winchester: St. Paul\u2019s Bibliographies, 1985, pp. 137\u2013137."},{"key":"bibr70-0967772013479285","unstructured":"Pruen T. A comparative sketch of the effects of variolous and vaccine inoculation, London: H Ruff, 1807, pp. 102\u2013102."},{"key":"bibr71-0967772013479285","unstructured":"The Gentleman\u2019s Magazine\n                      . 1803; 93: 571."},{"key":"bibr72-0967772013479285","unstructured":"Wellcome Library Images no 562352i."},{"key":"bibr73-0967772013479285","unstructured":"Hamilton J. London lights: the minds that moved the city that shook the world, London: John Murray, 2007, pp. 71\u20132, 342."},{"key":"bibr74-0967772013479285","unstructured":"Fraser M. Young Mr and Mrs Hall: 1823\u201330.\n                      The National Library of Wales Journal\n                      1964; 13: 29\u201347."},{"key":"bibr75-0967772013479285","unstructured":"Garlick K (op. cit. ref 6) Volume VI p.2226."},{"key":"bibr76-0967772013479285","unstructured":"Kassler M.\n                      Music entries at the Stationers Hall 1710\u20131818\n                      . Aldershot: Ashgate Publishing Ltd, 2004, p.462."},{"key":"bibr77-0967772013479285","unstructured":"Courtney WP. John Matthews (baptised 1755, d 1826), Reverend Claire L Nutt,\n                      Oxford Dictionary of National Biography\n                      , Oxford University Press, http:\/\/www.oxforddnb.com\/view\/article\/18345 (2004, accessed 26 January 2011)."},{"key":"bibr78-0967772013479285","unstructured":"From a bookseller\u2019s inventory, 2009."},{"key":"bibr79-0967772013479285","unstructured":"Miller G. Letters of Edward Jenner, and other documents concerning the early history of vaccination, Baltimore: John Hopkins University Press, c, 1983, pp. 65\u201367."},{"key":"bibr80-0967772013479285","unstructured":"Browne J. Thomas Andrew Knight (1759\u20131838),\n                      Oxford Dictionary of National Biography\n                      , Oxford University Press; online edition, May 2009, http:\/\/www.oxforddnb.com\/view\/article\/15737 (2004, accessed 26 January 2011)."},{"key":"bibr81-0967772013479285","unstructured":"Communications to the Horticultural Society.\n                      New Monthly Magazine\n                      1827; 21: 210."},{"key":"bibr82-0967772013479285","unstructured":"Records of the Sun Fire Office, Guildhall Library, MS 11936\/487\/980393."},{"key":"bibr83-0967772013479285","unstructured":"Hereford Journal\n                      11 Jun 1828 p.3 column 4."},{"key":"bibr84-0967772013479285","unstructured":"National Archives PROB 11\/1744."},{"key":"bibr85-0967772013479285","unstructured":"Cambrian quarterly magazine and Celtic repository 1830; 2: 259."}],"container-title":["Journal of Medical Biography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0967772013479285","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0967772013479285","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0967772013479285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:24:36Z","timestamp":1777505076000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0967772013479285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,4]]},"references-count":85,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1177\/0967772013479285"],"URL":"https:\/\/doi.org\/10.1177\/0967772013479285","relation":{},"ISSN":["0967-7720","1758-1087"],"issn-type":[{"value":"0967-7720","type":"print"},{"value":"1758-1087","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,4]]}}}