{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:44:33Z","timestamp":1777855473190,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2018,12,17]],"date-time":"2018-12-17T00:00:00Z","timestamp":1545004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Biogr"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:p>This article encapsulates the career of Joshua Burn, whose work encouraged new lines of experimentation and paved the way for fundamental advances in our knowledge of the autonomic nervous system. His legacy also endures in his efforts as Department Chairman to oversee a very supportive environment which led to the development of many successful scientists. By producing a body of work that enabled the discipline of pharmacology to contribute in a major way to the advancement of clinical medicine, Joshua Burn stands out as a unique figure in the annals of true scientific pioneers.<\/jats:p>","DOI":"10.1177\/0967772016685908","type":"journal-article","created":{"date-parts":[[2018,12,17]],"date-time":"2018-12-17T06:24:51Z","timestamp":1545027891000},"page":"61-65","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Joshua Harold Burn (1892\u20131981): A visionary during the evolution of pharmacology as a biomedical discipline"],"prefix":"10.1177","volume":"27","author":[{"given":"Ronald P","family":"Rubin","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Toxicology, Jacobs School of Medicine, the State University of New York at Buffalo, Buffalo, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,12,17]]},"reference":[{"key":"bibr1-0967772016685908","doi-asserted-by":"crossref","unstructured":"Bulbring E and Walker JM. Joshua Harold Burn. 6 March 1892\u201313 July 1981. Biogr Mem Fell R Soc (Nov) 1984; 30: 44\u201389; Vogt M. Obituary: Joshua Harold Burn (1892\u20131981).\n                      Rev Physiol Biochem Pharmacol\n                      1982; 94(1): 1\u201310. For a personal perspective see: Burn JH. Essential pharmacology.\n                      Annu Rev Pharmacol\n                      1969; 9(1): 1\u201321.","DOI":"10.1098\/rsbm.1984.0002"},{"key":"bibr2-0967772016685908","doi-asserted-by":"crossref","unstructured":"A inspirational reminiscence of Joshua Burn\u2019s accomplishments and unique attributes is chronicled in: Vane JR. J.H. Burn: an appreciation.\n                      Br J Pharmacol\n                      1982; 75(1): 3\u20137.","DOI":"10.1111\/j.1476-5381.1982.tb08751.x"},{"key":"bibr3-0967772016685908","unstructured":"Vogt M. Op. Cit. Ref. 1. pp. 3\u20134."},{"key":"bibr4-0967772016685908","first-page":"69","volume":"38","author":"Brading A","year":"1992","journal-title":"Biogr Mem Fell R Soc"},{"key":"bibr5-0967772016685908","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1941.sp003947"},{"key":"bibr6-0967772016685908","first-page":"245","volume":"4","author":"Bulbring E","year":"1949","journal-title":"Br J Pharmacol"},{"key":"bibr7-0967772016685908","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1949.sp004314"},{"key":"bibr8-0967772016685908","unstructured":"Dale Sir Henry H. Adventures in Physiology, London: The Wellcome Trust, Pergammon Press Ltd, 1953, pp. 35\u201335."},{"issue":"1","key":"bibr9-0967772016685908","first-page":"3","volume":"75","author":"Vane JR","year":"1982","journal-title":"J Pharmacol"},{"key":"bibr10-0967772016685908","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1993.tb13953.x"},{"key":"bibr11-0967772016685908","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1992.tb03797.x"},{"key":"bibr12-0967772016685908","unstructured":"Burn JH. Op. Cit. Ref. 1. pp. 11\u201312."},{"key":"bibr13-0967772016685908","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0022-3565(25)05585-5","volume":"30","author":"Tainter ML","year":"1927","journal-title":"J Pharmacol Exp Ther"},{"key":"bibr14-0967772016685908","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1931.sp002724"},{"key":"bibr15-0967772016685908","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1958.sp006104"},{"key":"bibr16-0967772016685908","doi-asserted-by":"crossref","unstructured":"Burn JH and Rand MJ. Sympathetic postganglionic mechanism.; Nature. 1959; 184: 163\u2013165.","DOI":"10.1038\/184163a0"},{"key":"bibr17-0967772016685908","doi-asserted-by":"crossref","unstructured":"Burn JH and Rand MJ. Sympathetic postganglionic fibres.\n                      Br J Pharmacol\n                      1997; Feb. 120: (Suppl. 1): 179\u2013180.","DOI":"10.1111\/j.1476-5381.1997.tb06796.x"},{"key":"bibr18-0967772016685908","doi-asserted-by":"crossref","unstructured":"Information negating the cholinergic link hypothesis can be found in: Muscholl E. From the cholinergic link to the cholinergic antilink in adrenergic transmission, the muscarinic inhibitory mechanism.\n                      Trends Pharmacol Sci\n                      1980; 1: 381\u2013382. Vincenzi F. J.H. Burn: a personal remembrance.\n                      Trends Pharmacol Sci\n                      1984; 5(6): 211\u2013212.","DOI":"10.1016\/0165-6147(80)90056-5"},{"key":"bibr19-0967772016685908","doi-asserted-by":"crossref","unstructured":"Trendelenburg U. Joshua Harold Burn. 6 March 1892\u201313 July 1981.\n                      Trends Pharmacol Sci\n                      1982; 3 (March): 91\u201392.","DOI":"10.1016\/0165-6147(82)91036-7"},{"key":"bibr20-0967772016685908","unstructured":"Vogt. M. Op. Cit. Ref. 1; pp. 7\u20138."}],"container-title":["Journal of Medical Biography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0967772016685908","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0967772016685908","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0967772016685908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:25:29Z","timestamp":1777505129000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0967772016685908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,17]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,2]]}},"alternative-id":["10.1177\/0967772016685908"],"URL":"https:\/\/doi.org\/10.1177\/0967772016685908","relation":{},"ISSN":["0967-7720","1758-1087"],"issn-type":[{"value":"0967-7720","type":"print"},{"value":"1758-1087","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,17]]}}}