{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:45:34Z","timestamp":1777855534284,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T00:00:00Z","timestamp":1623628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Biogr"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:p>John Goodsir, conservator and professor of anatomy at the University of Edinburgh, suffered an unidentified illness described by experts after his death as tabes. The features that led to this diagnosis, the understanding of tabes at that time and its relationship in some cases to syphilis, are discussed. It is concluded that the most likely diagnoses are subacute combined degeneration of the cord as a result of malnutrition or tabes dorsalis resulting from earlier syphilis. The presence of \u2018lightning pains\u2019 leans towards the latter diagnosis but evidence for a means of acquisition of syphilis is lacking. The disadvantages of retrospective diagnosis are discussed.<\/jats:p>","DOI":"10.1177\/09677720211021573","type":"journal-article","created":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T13:31:16Z","timestamp":1623677476000},"page":"65-74","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["John Goodsir (1814\u20131867) and his neurological illness"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2716-8500","authenticated-orcid":false,"given":"Iain","family":"Macintyre","sequence":"first","affiliation":[{"name":"Retired surgeon, Royal College of Surgeons of Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Gardner-Thorpe","sequence":"additional","affiliation":[{"name":"Consultant neurologist, Faculty of the History and Philosophy of Medicine and Pharmacy, Worshipful Society of Apothecaries, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2004-9448","authenticated-orcid":false,"given":"Andreas K","family":"Demetriades","sequence":"additional","affiliation":[{"name":"Consultant neurosurgeon, Royal Infirmary of Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,6,14]]},"reference":[{"key":"bibr1-09677720211021573","volume-title":"The anatomical memoirs of John Goodsir F.R.S. with a biographical memoir by Henry Lonsdale MD","author":"Lonsdale H","year":"1868"},{"key":"bibr2-09677720211021573","volume-title":"Anatomist. In Oxford dictionary of national biography","author":"Baston K.","year":"2004"},{"key":"bibr3-09677720211021573","unstructured":"Taylor H.\n                      John Goodsir 25th Proceedings of the Scottish Society of the History of Medicine\n                      . pp.  13\u2013 19,  1956. Available: https:\/\/sshm.ac.uk\/wp-content\/uploads\/2013\/08\/Proceedings-Session-1955-56.pdf#page=%22%201%20target=%22new%22"},{"key":"bibr4-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1177\/0967772015591716"},{"key":"bibr5-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1007\/BF00186676"},{"key":"bibr6-09677720211021573","doi-asserted-by":"publisher","DOI":"10.5962\/bhl.title.31604"},{"key":"bibr7-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1177\/096777200401200207"},{"key":"bibr8-09677720211021573","volume-title":"An Arctic voyage in search of friends with Sir John Franklin","author":"Goodsir R","year":"1850"},{"key":"bibr9-09677720211021573","doi-asserted-by":"publisher","DOI":"10.4997\/JRCPE.2020.225"},{"key":"bibr10-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1177\/0967772020942735"},{"key":"bibr11-09677720211021573","unstructured":"National Records of Scotland. John Goodsir Death Certificate. \n1867. North Leith, County of Edinburgh, number 80."},{"key":"bibr12-09677720211021573","volume-title":"The diseases of the spinal cord","author":"Bramwell B","year":"1882"},{"key":"bibr13-09677720211021573","first-page":"133","volume-title":"Edinburgh Medical Journal","volume":"30","author":"Bramwell B","year":"1923"},{"key":"bibr14-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1177\/0967772019868433"},{"key":"bibr15-09677720211021573","volume-title":"The Oxford English Dictionary","author":"Simpson JA","year":"1989"},{"key":"bibr16-09677720211021573","volume-title":"A history of the chronic degenerative diseases of the central nervous system","author":"Monro Thomas Kirkpatrick","year":"1895"},{"key":"bibr17-09677720211021573","volume-title":"Diseases of the nervous system","author":"Small AE","year":"1856"},{"key":"bibr18-09677720211021573","unstructured":"Gowers W. Manual of diseases of the nervous system. 2nd ed.  London:  J&A Churchill;  1892\u2013 1899."},{"key":"bibr19-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.24.2.187"},{"key":"bibr20-09677720211021573","volume-title":"The diagnosis of disease of the spinal cord. An address delivered to the Medical Society of Wolverhampton, October 9th, 1879","author":"Gowers W","year":"1881"},{"key":"bibr21-09677720211021573","volume-title":"Practical essays and remarks on that species of consumption incident to youth, and the different stages of life, commonly called tabes dorsalis with an account of the nature, causes, and cure of that distemper","author":"Neale HSJ","year":"1809","edition":"3"},{"key":"bibr22-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-197607000-00001"},{"key":"bibr23-09677720211021573","volume-title":"A manual of the nervous diseases of man","author":"Romberg M","year":"1853"},{"key":"bibr24-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.57.4.605"},{"key":"bibr25-09677720211021573","volume-title":"A clinical treatise on the diseases of the nervous system","author":"Rosenthal M","year":"1879"},{"key":"bibr26-09677720211021573","volume-title":"The brain and its diseases part I. Syphilis of the brain and spinal cord","author":"Dowse T","year":"1879"},{"key":"bibr27-09677720211021573","volume-title":"Clinical lectures on diseases of the nervous system","author":"Buzzard T","year":"1882"},{"key":"bibr28-09677720211021573","unstructured":"Doyle A.  An Essay Upon the Vasomotor Changes in Tabes Dorsalis and on the Influence Which is Exerted by the Sympathetic Nervous System in That Disease.  1885. MD thesis. University of Edinburgh."},{"key":"bibr29-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03320300050022"},{"key":"bibr30-09677720211021573","unstructured":"University of Edinburgh Library Special Collections. GB 237; Gen 291, 292, 391, 305, 306."},{"key":"bibr31-09677720211021573","doi-asserted-by":"publisher","DOI":"10.3366\/anh.1981.10.2.205"},{"key":"bibr32-09677720211021573","unstructured":"Banks W.  Introductory address to the Anatomical Society of the University of Liverpool.  Liverpool:  Liverpool University Press;  1906."},{"key":"bibr33-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1993.00410210057007"},{"key":"bibr34-09677720211021573","first-page":"129","volume":"14","author":"Morrow PA","year":"1896","journal-title":"Journal of Cutaneous Genito-Urinary Disorders"},{"key":"bibr35-09677720211021573","first-page":"449","volume":"11","author":"Bulkley L","year":"1890","journal-title":"International Dental Journal"},{"key":"bibr36-09677720211021573","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/23.1.39"},{"key":"bibr37-09677720211021573","first-page":"959","volume":"12","author":"Anonymous","year":"1867","journal-title":"Edinburgh Medical Journal"}],"container-title":["Journal of Medical Biography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09677720211021573","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09677720211021573","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09677720211021573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:26:14Z","timestamp":1777505174000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09677720211021573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,14]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1177\/09677720211021573"],"URL":"https:\/\/doi.org\/10.1177\/09677720211021573","relation":{},"ISSN":["0967-7720","1758-1087"],"issn-type":[{"value":"0967-7720","type":"print"},{"value":"1758-1087","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,14]]}}}