{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:45:42Z","timestamp":1777855542367,"version":"3.51.4"},"reference-count":58,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,11,6]],"date-time":"2021-11-06T00:00:00Z","timestamp":1636156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Biogr"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:p>On 23 September 1919, Sir William Osler, after a telephone call from his friend Dyson Perrins, went to Glasgow where he saw a 40-year-old woman, Bethia Fulton Martin, in consultation with three local physicians. Osler called it \u201cone of those remarkable Erythema cases (all sorts of skin lesions and three months on and off consolidation of both lower lobes).\u201d Mrs Martin died 114 days later; her death certificate listed \u201cangioneurotic oedema with chronic nephritis\u201d and \u201ctuberculous enlargement of the mediastinal lymph nodes.\u201d Osler died 18 days before Mrs Martin of complications from a respiratory infection acquired on his way home from Scotland. We discuss factors that possibly prompted Osler to go to Scotland, including his role with the newly formed University Grants Committee, and the differential diagnosis of the case, which is mainly between systemic lupus erythematosus and Henoch-Sch\u00f6nlein purpura.<\/jats:p>","DOI":"10.1177\/09677720211052613","type":"journal-article","created":{"date-parts":[[2021,11,6]],"date-time":"2021-11-06T11:35:30Z","timestamp":1636198530000},"page":"261-267","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Sir William Osler's fatal trip to Scotland: \u201cMrs M\u201d and the University Grants Committee"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6977-6507","authenticated-orcid":false,"given":"Graham","family":"Kyle","sequence":"first","affiliation":[{"name":"Royal College of Surgeons of Edinburgh, Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9329-7215","authenticated-orcid":false,"given":"Charles S","family":"Bryan","sequence":"additional","affiliation":[{"name":"Royal College of Surgeons of Edinburgh, Edinburgh, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,11,6]]},"reference":[{"key":"bibr1-09677720211052613","unstructured":"Cushing H. The life of Sir William Osler.  Oxford:  Clarendon Press,  1925;  ii:  668."},{"key":"bibr2-09677720211052613","unstructured":"Bliss M. William Osler: A Life in Medicine.  New York:  Oxford University Press,  1999:  467. A guinea was 21 shillings and was the usual denomination in which British professional fees were charged at the time. Osler's fee of \u00a3525 in September 1919 would have the purchasing power of \u00a324,675, or $34,305 US, in 2021. For a discussion of Osler's fees, see the article on Osler's practice by George T. Harrell, Jr. (ref. 21). Harrell estimated Osler's income for 1919 to have been \u00a33,650, of which \u00a3620 came from dividends and \u00a3600 from book royalties. Osler's salary was \u00a3679 in 1912, but his day book does not record a salary thereafter. Osler's day book does not list a salary for 1919. If we assume that he received a salary of \u00a3679 during 1919, and that all of the remaining income came from consulting fees, his fee for seeing Mrs Martin would have been 30 percent of his practice income for the year."},{"key":"bibr3-09677720211052613","first-page":"217","volume-title":"The Persisting Osler\u2014V. Selected Transactions of the American Osler Society 2011\u20132020","author":"Ward JWK","year":"2021"},{"key":"bibr4-09677720211052613","unstructured":"1879 Wylie, Bethia. Statutory registers Births 646\/2 764, National Records of Scotland."},{"key":"bibr5-09677720211052613","unstructured":"https:\/\/billiongraves.com\/grave\/Hugh-Fulton-Martin\/30295918, accessed 10 May 2021."},{"key":"bibr6-09677720211052613","unstructured":"William Adam Wylie,  Obituary, The Scotsman, 15 December 1939."},{"key":"bibr7-09677720211052613","unstructured":"1913 Wylie, Bethia. Statutory registers Marriages 644.12 76, National Records of Scotland."},{"key":"bibr8-09677720211052613","unstructured":"Records of W & J Martin (Glasgow) Ltd (leather merchants, tanners and footwear manufacturers, c1830\u20131981: Bridge of Weir, Renfrewshire, Scotland, University of Glasgow Archive Services, GB 248, UGD 167."},{"key":"bibr9-09677720211052613","unstructured":"[Unsigned news item].\n                      Saddlery and Harness\n                      .\n                      A Monthly Trade Journal\n                      1903\u20131904; 13: 14 (also, advertisements throughout this volume)."},{"key":"bibr10-09677720211052613","unstructured":"1914 Martin, W.W. Statutory registers Births 498\/ 249, National Records of Scotland."},{"key":"bibr11-09677720211052613","unstructured":"General register of Sasines for the County of Glasgow, Sheet no. 11771."},{"key":"bibr12-09677720211052613","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1136\/bmj.2.4891.814","volume":"2","author":"Ness R. Barclay","year":"1954","journal-title":"British Medical Journal"},{"key":"bibr13-09677720211052613","unstructured":"Agnes Cameron. https:\/\/universitystory.gla.ac.uk\/biography\/?id=WH3025&type=P, accessed 29 July 2020."},{"key":"bibr14-09677720211052613","first-page":"21","volume":"125","author":"Armstrong William Buchanan","year":"1936","journal-title":"Glasgow Medical Journal"},{"key":"bibr15-09677720211052613","unstructured":"1913 Wylie, Bethia. Statutory registers Marriages 644\/12 76, National Records of Scotland."},{"key":"bibr16-09677720211052613","first-page":"422","volume":"48","author":"Gulland George Lovell","year":"1941","journal-title":"Edinburgh Medical Journal"},{"key":"bibr17-09677720211052613","doi-asserted-by":"crossref","unstructured":"Littlejohn HarveyM.B., C.M., B.Sc.Ed., F.R.C.S., F.R.S. Ed. British Medical Journal 1927;  2:  369\u2012 370.","DOI":"10.1136\/bmj.2.3477.369"},{"key":"bibr18-09677720211052613","volume-title":"The life of Sir William Osler","author":"Cushing H","year":"1925"},{"key":"bibr19-09677720211052613","unstructured":"Bibliotheca Osleriana Osler W. A catalogue of books illustrating the history of medicine and science collected, arranged, and annotated by Sir William Osler, Bt. and Bequeathed to McGill University.  Oxford:  Clarendon Press,  1929:  395 (item 4368)."},{"key":"bibr20-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1969.03160380047010"},{"key":"bibr21-09677720211052613","first-page":"545","volume":"47","author":"Harrell GT","year":"1973","journal-title":"Bulletin of the History of Medicine"},{"key":"bibr22-09677720211052613","first-page":"359","volume-title":"Sir William Osler: An Encyclopedia","author":"Bryan CS","year":"2020"},{"key":"bibr23-09677720211052613","first-page":"194","volume-title":"Sir William Osler: An Encyclopedia","author":"Bryan CS","year":"2020"},{"key":"bibr24-09677720211052613","volume-title":"The life of Sir William Osler","author":"Cushing H","year":"1925"},{"key":"bibr25-09677720211052613","volume-title":"The life of Sir William Osler","author":"Cushing H","year":"1925"},{"key":"bibr26-09677720211052613","unstructured":"Bliss M. William Osler: A life in medicine.  New York:  Oxford University Press,  1999:  465\u2012 466."},{"key":"bibr27-09677720211052613","unstructured":"The Osler Library of the History of Medicine at McGill University contains two letters from Monro to Osler written during 1918 (Osler Letter Index, CUS417\/35.27 and CUS417\/35\/20) and two additional items pertaining (or probably pertaining) to Monro during 1919 (CUS417\/4.34 and CUS 417\/128.93)."},{"key":"bibr28-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1007\/BF01096178"},{"key":"bibr29-09677720211052613","first-page":"188","volume":"2","author":"Presentation to Sir William Osler, F.R.S., Bart","year":"1919","journal-title":"Annals of Medical History"},{"key":"bibr30-09677720211052613","unstructured":"William Osler to George Newman, 24 July 1919. Osler Letter Index, CUS417\/58.39. Osler Library of the History of Medicine, McGill University."},{"key":"bibr31-09677720211052613","unstructured":"William Osler to John George Adami, 4 October 1919. Osler Letter Index, CUS417\/103.9. Osler Library of the History of Medicine, McGill University, Montreal."},{"key":"bibr32-09677720211052613","unstructured":"Osler to William Sydney Thayer, Thomas McCrae, and Thomas Barnes Futcher, 27 October 1919. CUS 417\/130.39. Cushing papers, Osler Library of the History of Medicine, McGill University."},{"key":"bibr33-09677720211052613","unstructured":"1920 Wylie, Bethia. Statutory registers Deaths 644\/12 73, National Records of Scotland."},{"key":"bibr34-09677720211052613","unstructured":"Bethia Wylie Martin's father died at age 83 with chronic nephritis and myocardial degeneration. Her mother died at age 69 with cerebral endarteritis, left hemiplegia, and bronchopneumonia. Her paternal grandfather died at age 37 of \u2018phthis pulmonaria\u2019. (pulmonary tuberculosis), and her paternal grandmother died at age 78 of bronchitis and \u2018senile heart\u2019. Her maternal grandfather died at age 87 of \u2018general debility and old age\u2019, and her maternal grandmother died at age 42 of \u2018enlargement of the liver\u2019 of 10 years\u2019 duration and hematemesis of 10 days\u2019 duration. We obtained no family history of arthritis or rheumatic disease."},{"key":"bibr35-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-189512000-00001"},{"key":"bibr36-09677720211052613","first-page":"227","volume":"12","author":"Osler W","year":"1900","journal-title":"British Journal of Dermatology"},{"key":"bibr37-09677720211052613","first-page":"599","volume":"18","author":"Osler W","year":"1903","journal-title":"Transactions of the Association of American Physicians"},{"key":"bibr38-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-190401000-00001"},{"key":"bibr39-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.2775.517"},{"key":"bibr40-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-0172(97)80037-6"},{"key":"bibr41-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e3181acbd71"},{"key":"bibr42-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928"},{"key":"bibr43-09677720211052613","first-page":"47","volume":"85","author":"Tumulty PA","year":"1949","journal-title":"Bulletin of the Johns Hopkins Hospital"},{"key":"bibr44-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.02.003"},{"key":"bibr45-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-188804000-00004"},{"key":"bibr46-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1186\/s13223-020-00437-x"},{"key":"bibr47-09677720211052613","volume":"1","author":"Tran JP","year":"2017","journal-title":"Journal of Autoimmune and Systemic diseases"},{"key":"bibr48-09677720211052613","author":"Kumar N","year":"2018","journal-title":"BMJ Case Reports"},{"key":"bibr49-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(03)00744-8"},{"key":"bibr50-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1177\/0961203317709347"},{"key":"bibr51-09677720211052613","first-page":"306","volume":"31","author":"L\u00f6ffler C","year":"2015","journal-title":"Sarcoidosis, Vasculitis & Diffuse Lung Diseases"},{"key":"bibr52-09677720211052613","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.215120"},{"key":"bibr53-09677720211052613","doi-asserted-by":"publisher","DOI":"10.2174\/1573397115666191021154628"},{"key":"bibr54-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-017-8616-5"},{"key":"bibr55-09677720211052613","unstructured":"William Osler to William McCormick, 6 October 1919. Osler Letter Index, CUS417\/130.15, Osler Library of the History of Medicine, McGill University."},{"key":"bibr56-09677720211052613","unstructured":"William Osler to George Newman, 6 October 1919. Osler Letter Index, CUS417\/130.14, Osler Library of the History of Medicine, McGill University."},{"key":"bibr57-09677720211052613","unstructured":"Minutes of the University Grants Committee, 9 October 1919 and 13 November 1919, Records of the University Grants Committee, 1919\u20131988, The National Archives, Kew."},{"key":"bibr58-09677720211052613","doi-asserted-by":"publisher","DOI":"10.1080\/0046760X.2020.1836263"}],"container-title":["Journal of Medical Biography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09677720211052613","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09677720211052613","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09677720211052613","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:26:21Z","timestamp":1777505181000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09677720211052613"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,6]]},"references-count":58,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["10.1177\/09677720211052613"],"URL":"https:\/\/doi.org\/10.1177\/09677720211052613","relation":{},"ISSN":["0967-7720","1758-1087"],"issn-type":[{"value":"0967-7720","type":"print"},{"value":"1758-1087","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,6]]}}}