{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:40:25Z","timestamp":1790685625016,"version":"4.1.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2016,5,19]],"date-time":"2016-05-19T00:00:00Z","timestamp":1463616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Screen"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Although cervical cancer screening guidelines in France recommend a smear test every three years, many physicians order more regular screening. We aimed to assess the benefits or harms of shorter intervals between screenings, both for women and public health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>For a retrospective cohort of women aged 25\u201365 who had two normal smears and at least one additional smear, data were sourced from a regionally organized cervical cancer screening programme in France, with follow-up for nine years. Based on the interval between the second and third smear, two groups were formed; the first comprised overscreened women (interval &lt;24 months), and the second of \u2018correctly\u2019 screened women (interval between 24 and 42 months). The primary outcome was cervical intraepithelial neoplasia 2 or worse (CIN2+); secondary outcomes were cervical cancers and CIN1 lesions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 63,821 women, CIN2+ incidence rate per 10,000 women per year was 14.5 for 40,350 overscreened women, and 11.5 for 23,471 correctly screened women. Age-adjusted relative risk was 1.22[1.02; 1.46]. We found no significant difference for cancer (RR\u2009=\u20091.39; 95%CI\u2009=\u2009[0.60; 3.61]), but did find additional CIN1 in the overscreened group (RR\u2009=\u20092.09; 95%CI\u2009=\u2009[1.76; 2.51]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A shorter interval between smears has a low benefit for CIN2+ lesion detection, which may not help avoid cancer. The excess number of CIN1 detected by overscreening may cause needless risk and excess costs due to overtreatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0969141316647091","type":"journal-article","created":{"date-parts":[[2016,5,22]],"date-time":"2016-05-22T14:16:12Z","timestamp":1463926572000},"page":"92-97","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Excess cervical cancer screening smears: Any benefit? A retrospective cohort in Alsace, France"],"prefix":"10.1177","volume":"24","author":[{"given":"Alicia","family":"Thiery","sequence":"first","affiliation":[{"name":"Eve Association, Illkirch-Graffenstaden, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cherif","family":"Akladios","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University Hospital Strasbourg, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muriel","family":"Fender","sequence":"additional","affiliation":[{"name":"Eve Association, Illkirch-Graffenstaden, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Severac","sequence":"additional","affiliation":[{"name":"Department of Public Health, University Hospital Strasbourg, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Jacques","family":"Baldauf","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University Hospital Strasbourg, Strasbourg, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,5,19]]},"reference":[{"key":"bibr1-0969141316647091","first-page":"5bis","volume":"19","author":"Renaud R","year":"1990","journal-title":"J Gyn\u00e9cologie Obst\u00e9trique Biol Reprod"},{"key":"bibr2-0969141316647091","volume-title":"Etat des lieux et recommandations pour le d\u00e9pistage du cancer du col de l\u2019ut\u00e9rus en France","author":"Haute Autorit\u00e9 de Sant\u00e9","year":"2010"},{"key":"bibr3-0969141316647091","volume-title":"Le d\u00e9pistage du cancer du col ut\u00e9rin en France. 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