{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T12:29:40Z","timestamp":1793104180028,"version":"4.5.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T00:00:00Z","timestamp":1647907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Screen"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Previously, based on 6 months of follow-up, we showed that HPV self-sampling improved participation in cervical screening compared to a reminder letter for Pap testing for never- and under-screened women. Here, we report follow-up and related screening outcomes for women who participated in the initial self-sampling over two screening rounds.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>The randomised controlled trial was conducted in Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Never- and under-screened women were randomly allocated to the HPV self-sampling or the reminder for Pap test arm and followed at 6 and 36 months since the kits were first mailed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The first round of HPV self-sampling kits were mailed from May\u2013July 2014 to 12 572 women. After 36 months, 19% of never-screened and 9% of under-screened women returned a kit for HPV testing; 2.7% were HPV 16\/18 and 5.8% non-16\/18 HPV positive. Compliance with first round follow-up was 84% (95% CI: 77.1\u201389.5%). Non-compliant and cytology triage negative women were mailed another kit at 12 months. Compliance at 12-month follow-up was 59.3% (49.4 to 68.6%). Of 37 women with a 12-month repeat HPV, 70% were positive. Of women who tested negative for HPV in the first round (n\u2009=\u20091573), 25% attended regular screening in the next round and none had CIN2\u2009+\u2009detected. The overall prevalence of CIN2\u2009+\u2009was 8.5 per 1000 screened (4.8 to 13.9 per 1000).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>While self-sampling can successfully engage women, compliance with repeat testing may require monitoring. The clinician-supported self-collection pathway now in use in Australia will likely improve women's engagement with follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09691413221080635","type":"journal-article","created":{"date-parts":[[2022,3,22]],"date-time":"2022-03-22T03:04:49Z","timestamp":1647918289000},"page":"185-193","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["HPV self-sampling and follow-up over two rounds of cervical screening in Australia \u2013 the iPap trial"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8360-1116","authenticated-orcid":false,"given":"Farhana","family":"Sultana","sequence":"first","affiliation":[{"name":"formerly VCS Population Health, VCS Foundation, East Melbourne, Victoria, Australia"},{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia"},{"name":"Population Health Solutions, Telstra Health, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota M","family":"Gertig","sequence":"additional","affiliation":[{"name":"formerly VCS Population Health, VCS Foundation, East Melbourne, Victoria, Australia"},{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia"},{"name":"Population Health Solutions, Telstra Health, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dallas R","family":"English","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia"},{"name":"Cancer Council Victoria, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A","family":"Simpson","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly T","family":"Drennan","sequence":"additional","affiliation":[{"name":"formerly VCS Population Health, VCS Foundation, East Melbourne, Victoria, Australia"},{"name":"Population Health Solutions, Telstra Health, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C David","family":"Wrede","sequence":"additional","affiliation":[{"name":"Dysplasia Clinic, The Royal Women\u2019s Hospital, Parkville, Victoria, Australia"},{"name":"Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6828-719X","authenticated-orcid":false,"given":"Robyn M","family":"Mullins","sequence":"additional","affiliation":[{"name":"Australian Institute for Primary Care & Ageing, College of Science, Health and Engineering, La Trobe University, Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stella","family":"Heley","sequence":"additional","affiliation":[{"name":"formerly VCS Population Health, VCS Foundation, East Melbourne, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Saville","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, University of Melbourne, Parkville, Victoria, Australia"},{"name":"VCS Foundation, Carlton, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia ML","family":"Brotherton","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia"},{"name":"VCS Foundation, Carlton, Victoria, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,3,22]]},"reference":[{"key":"bibr1-09691413221080635","unstructured":"Cancer Council Australia Cervical Cancer Screening Guidelines Working Party. National cervical screening program: guidelines for the management of screen-detected abnormalities, screening in specific populations and investigation of abnormal vaginal bleeding. Cancer Council Australia, Sydney, 2016. www.wiki.cancer.org.au (last accessed November 26, 2021)"},{"key":"bibr2-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k4823"},{"key":"bibr3-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.30031"},{"key":"bibr4-09691413221080635","doi-asserted-by":"publisher","DOI":"10.5694\/mja15.00912"},{"key":"bibr5-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-14-207"},{"key":"bibr6-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.236"},{"key":"bibr7-09691413221080635","unstructured":"Victorian Cervical Cytology Registry (VCCR). http:\/\/www.vccr.org\/ (accessed May 24, 2018)."},{"key":"bibr8-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-015-1804-x"},{"key":"bibr9-09691413221080635","doi-asserted-by":"publisher","DOI":"10.3747\/co.25.3916"},{"key":"bibr10-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1071\/SH14236"},{"key":"bibr11-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c1040"},{"key":"bibr12-09691413221080635","unstructured":"Medical Services Advisory Committee. Public summary document: application No. 1664. Improvements to the national cervical screening program self-collection policy. Available at: http:\/\/www.msac.gov.au\/internet\/msac\/publishing.nsf\/Content\/1664-public (last accessed November 26, 2021)"},{"key":"bibr13-09691413221080635","volume-title":"Implementation of Australia\u2019s Renewed Cervical Screening Program: Perspectives from Practitioners","author":"Sultana F","year":"2018"},{"key":"bibr14-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.8389"},{"key":"bibr15-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.26128"},{"key":"bibr16-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.11.022"},{"key":"bibr17-09691413221080635","unstructured":"Victorian Cervical Cytology Registry (VCCR). Victorian cervical cytology registry statistical report 2015. 2015. https:\/\/www.vcs.org.au\/population-health\/statistical-reports\/annual-statistical-reports\/?issuu=NTgyOTkzMDh8U3RhdGlzdGljYWwgUmVwb3J0IDIwMTU= (last accessed November 26, 2021)."},{"key":"bibr18-09691413221080635","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2015.06.080"}],"container-title":["Journal of Medical Screening"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09691413221080635","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09691413221080635","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09691413221080635","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:25:22Z","timestamp":1777677922000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09691413221080635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,22]]},"references-count":18,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1177\/09691413221080635"],"URL":"https:\/\/doi.org\/10.1177\/09691413221080635","relation":{},"ISSN":["0969-1413","1475-5793"],"issn-type":[{"value":"0969-1413","type":"print"},{"value":"1475-5793","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,22]]}}}