{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:16:56Z","timestamp":1790036216483,"version":"4.0.1"},"reference-count":39,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T00:00:00Z","timestamp":1721865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100013297","name":"Eurostars","doi-asserted-by":"publisher","award":["5091 \u2013 00036B"],"award-info":[{"award-number":["5091 \u2013 00036B"]}],"id":[{"id":"10.13039\/100013297","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Screen"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess performance endpoints of a combination of digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) compared with FFDM only in breast cancer screening.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and methods<\/jats:title>\n                    <jats:p>This was a prospective population-based screening study, including eligible (50\u201369 years) women attending the Capital Region Mammography Screening Program in Denmark. All attending women were offered FFDM. A subgroup was consecutively allocated to a screening room with DBT. All FFDM and DBT underwent independent double reading, and all women were followed up for 2 years after screening date or until next screening date, whichever came first.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>6353 DBT\u2009+\u2009FFDM and 395 835 FFDM were included in the analysis and were undertaken in 196 267 women in the period from 1 November 2012 to 12 December 2018. Addition of DBT increased sensitivity: 89.9% (95% confidence interval (CI): 81.0\u201395.5) for DBT\u2009+\u2009FFDM and 70.1% (95% CI: 68.6\u201371.6) for FFDM only, p\u2009&lt;\u20090.001. Specificity remained similar: 98.2% (95% CI: 97.9\u201398.5) for DBT\u2009+\u2009FFDM and 98.3% (95% CI: 98.2\u201398.3) for FFDM only, p\u2009=\u20090.9. Screen-detected cancer rate increased statistically significantly: 11.18\/1000 for DBT\u2009+\u2009FFDM and 6.49\/1000 for FFDM only, p\u2009&lt;\u20090.001. False-positive rate was unchanged: 1.75% for DBT\u2009+\u2009FFDM and 1.73% for FFDM only, p\u2009=\u20090.9. Positive predictive value for recall was 39.0% (95% CI: 31.9\u201346.5) for DBT\u2009+\u2009FFDM and 27.3% (95% CI: 26.4\u201328.2), for FFDM only, p\u2009&lt;\u20090.0005. The interval cancer rate decreased: 1.26\/1000 for DBT\u2009+\u2009FFDM and 2.76\/1000 for FFDM only, p\u2009=\u20090.02.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>DBT\u2009+\u2009FFDM yielded a statistically significant increase in cancer detection and program sensitivity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09691413241262259","type":"journal-article","created":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T18:26:26Z","timestamp":1721931986000},"page":"28-34","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Introduction of one-view tomosynthesis in population-based mammography screening: Impact on detection rate, interval cancer rate and false-positive rate"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1924-9039","authenticated-orcid":false,"given":"Bolette Mikela","family":"Vilmun","sequence":"first","affiliation":[{"name":"Department of Diagnostic Radiology, Copenhagen University Hospital, Copenhagen, Denmark"},{"name":"Department of Breast Examinations, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark"},{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Napolitano","sequence":"additional","affiliation":[{"name":"Department of Public Health, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Lillholm","sequence":"additional","affiliation":[{"name":"Biomediq A\/S, Drag\u00f8r, Denmark"},{"name":"Department of Computer Science, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rikke Rass","family":"Winkel","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Copenhagen University Hospital, Copenhagen, Denmark"},{"name":"Department of Radiology, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elsebeth","family":"Lynge","sequence":"additional","affiliation":[{"name":"Nyk\u00f8bing Falster Hospital, University of Copenhagen, Nyk\u00f8bing Falster, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mads","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Biomediq A\/S, Drag\u00f8r, Denmark"},{"name":"Department of Computer Science, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael Bachmann","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Copenhagen University Hospital, Copenhagen, Denmark"},{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan Frederik","family":"Carlsen","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Copenhagen University Hospital, Copenhagen, Denmark"},{"name":"Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"My","family":"von Euler-Chelpin","sequence":"additional","affiliation":[{"name":"Department of Public Health, University of Copenhagen, Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilse","family":"Vejborg","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Copenhagen University Hospital, Copenhagen, Denmark"},{"name":"Department of Breast Examinations, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,7,25]]},"reference":[{"key":"bibr1-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08020-0"},{"key":"bibr2-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2018.78.0270"},{"key":"bibr3-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38313.639236.82"},{"key":"bibr4-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-016-2450-7"},{"key":"bibr5-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2017.05.006"},{"key":"bibr6-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1136\/jms.5.4.207"},{"key":"bibr7-09691413241262259","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8112021"},{"key":"bibr8-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2013.01.017"},{"key":"bibr9-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30521-7"},{"key":"bibr10-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-018-5690-x"},{"key":"bibr11-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2018172119"},{"key":"bibr12-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2019182394"},{"key":"bibr13-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-013-2820-3"},{"key":"bibr14-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djy121"},{"key":"bibr15-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-64802-x"},{"key":"bibr16-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-023-09705-x"},{"key":"bibr17-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020202858"},{"key":"bibr18-09691413241262259","volume-title":"European guidelines for quality assurance in breast cancer screening and diagnosis","author":"European Commission","year":"2006"},{"key":"bibr19-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.230964"},{"key":"bibr20-09691413241262259","author":"D\u2019orsi CJ","year":"2003","journal-title":"Am Coll Radiol"},{"key":"bibr21-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3803-3"},{"key":"bibr22-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2019.09.012"},{"key":"bibr23-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70134-7"},{"key":"bibr24-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020201246"},{"key":"bibr25-09691413241262259","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(22)00194-2"},{"key":"bibr26-09691413241262259","doi-asserted-by":"crossref","unstructured":"Houssami N, Zackrisson S, Blazek K, et al. 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