{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T04:46:23Z","timestamp":1783658783522,"version":"3.55.0"},"reference-count":40,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T00:00:00Z","timestamp":1725840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","award":["20220282"],"award-info":[{"award-number":["20220282"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Med Screen"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The psychological consequences of being aware of an increased risk of developing abdominal aortic aneurysm as a first-degree relative of a person with abdominal aortic aneurysm are hitherto unexplored. This study investigates the awareness of heritability and anxiety in male and female adult offspring of abdominal aortic aneurysm patients compared to controls. Health-related quality of life among participants with aortic pathology was compared to participants with normal aortic diameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a cross-sectional point prevalence study based on the participants examined in the Detecting Abdominal Aortic Aneurysm in First Degree Relatives Trial (DAAAD; 752 adult offspring, 756 matched controls), 2020\u20132022. Questionnaires about health-related quality of life and study-specific questions regarding awareness of heritability were collected prior to the aortic ultrasound.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Attendance rate was higher among individuals with heredity compared to controls (67% vs. 52%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Of 1508 adult offspring examined, 65% reported having a close relative with abdominal aortic aneurysm (6% in controls). Female adult offspring reported higher awareness of heritability than controls (38% vs. 12%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001), as did males (32% vs. 8%,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009&lt;\u20090.001). A slight majority of participants with awareness reported anxiety (54% of female offspring; 51% of male). There were no measured differences in health-related quality of life between the groups when standard health-related quality of life instruments were used.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The higher-than-expected proportion of adult offspring with awareness of heritability and anxiety about such risk indicates that we fail to communicate risk to this group appropriately via the current channels of information within the healthcare system. This calls for the development of dedicated strategies for improved communication of abdominal aortic aneurysm risk to patients and their next of kin.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09691413241278224","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T09:16:53Z","timestamp":1725959813000},"page":"67-75","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Anxiety and disease awareness in individuals with heredity for abdominal aortic aneurysm"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9504-8180","authenticated-orcid":false,"given":"Nina","family":"Fattahi","sequence":"first","affiliation":[{"name":"Karolinska Institutet"},{"name":"S\u00f6dersjukhuset AB"},{"name":"Karolinska Institutet"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Nilsson","sequence":"additional","affiliation":[{"name":"Karolinska Institutet"},{"name":"Karolinska University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sverker","family":"Svensj\u00f6","sequence":"additional","affiliation":[{"name":"Uppsala University"},{"name":"Department of Surgery, Centre for Clinical Research Dalarna"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy","family":"Roy","sequence":"additional","affiliation":[{"name":"Karolinska Institutet"},{"name":"Karolinska University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anneli","family":"Linn\u00e9","sequence":"additional","affiliation":[{"name":"Karolinska Institutet"},{"name":"S\u00f6dersjukhuset AB"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecka","family":"Hultgren","sequence":"additional","affiliation":[{"name":"Karolinska Institutet"},{"name":"Karolinska University Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,9,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2013.11.005"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2008.08.012"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2012.01.061"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000186168.56571.91"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X16686409"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10715"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.022305"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10721"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2018.10.012"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-1433.2004.03270.x"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2019.07.021"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(00)00426-3"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/pop.2012.0044"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)11522-4"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.5999"},{"key":"e_1_3_3_17_2","doi-asserted-by":"crossref","unstructured":"Fattahi N Linn\u00e9 A Roy J et al. 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