{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:28:02Z","timestamp":1777415282061,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"3-4","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Annals of Neurosciences"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Progressive neurological genetic diseases are not rare. They cause psychosocial damages to its victims. This article focuses on common psychosocial issues faced by those from the developing world.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A multicentre observational survey of 246 patients from teaching hospitals in Sri Lanka. Participants were clinically and genetically confirmed by neurologists and the Interdisciplinary Centre for Innovation in Biotechnology and Neuroscience (ICIBN) respectively from 2014 to 2018. Convenience sample with random geographical distribution. Factors were equally weighted. ANOVA, Student\u2019s t-test and chi-square analysis were used. Statistical Software R Statistics\u2014version 3.5 and one-sample t-test with CI = 95% was used. This study meets the ethical guidelines of the local institutional review boards which are in compliance with the Helsinki Declaration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Sample included 184 males and 62 females of 3\u201376 years with either Duchenne muscular dystrophy (n=121), spinocerebellar ataxia ( n = 87) or Huntington disease ( n = 38). Mean income of the affected is lower than the standard average monthly income ( P \u2264 .001). Consultation visits depend on the monthly income (CI 20421.074\u201334709.361; P \u2264 .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Poverty is inversely proportionate to the patients\u2019 living conditions. As developing countries are financially challenged, it is a societal challenge to rebuild our values to enhance their living status.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0972753120950069","type":"journal-article","created":{"date-parts":[[2020,11,13]],"date-time":"2020-11-13T06:06:53Z","timestamp":1605247613000},"page":"91-97","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["What We Fail to See in Neuro-Genetic Diseases: A Bird\u2019s Eye View from the Developing World"],"prefix":"10.1177","volume":"27","author":[{"given":"Navami","family":"Samaranayake","sequence":"first","affiliation":[{"name":"Interdisciplinary Centre for Innovation in Biotechnology and Neuroscience, University of Sri Jayewardenepura, Nugegoda, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pulasthi","family":"Dissanayaka","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre for Innovation in Biotechnology and Neuroscience, University of Sri Jayewardenepura, Nugegoda, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isuru","family":"Gunarathna","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre for Innovation in Biotechnology and Neuroscience, University of Sri Jayewardenepura, Nugegoda, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lakmal","family":"Gonawala","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre for Innovation in Biotechnology and Neuroscience, University of Sri Jayewardenepura, Nugegoda, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nalaka","family":"Wijekoon","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre for Innovation in Biotechnology and Neuroscience, University of Sri Jayewardenepura, Nugegoda, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pyara","family":"Rathnayake","sequence":"additional","affiliation":[{"name":"Lady Ridgeway Hospital for Children, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darshana","family":"Sirisena","sequence":"additional","affiliation":[{"name":"National Hospital of Sri Lanka, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harsha","family":"Gunasekara","sequence":"additional","affiliation":[{"name":"Sri Jayewardenepura General Hospital, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athula","family":"Dissanayake","sequence":"additional","affiliation":[{"name":"Teaching Hospital Karapitiya, Galle, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunethra","family":"Senanayake","sequence":"additional","affiliation":[{"name":"National Hospital of Sri Lanka, Colombo, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akshay","family":"Anand","sequence":"additional","affiliation":[{"name":"Neuroscience Research Lab, Institute of Medical Education and Research (PGIMER), Chandigarh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kapaettu","family":"Satyamoorthy","sequence":"additional","affiliation":[{"name":"Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashwin","family":"Dalal","sequence":"additional","affiliation":[{"name":"Centre for DNA Fingerprinting and Diagnostics, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8738-9412","authenticated-orcid":false,"given":"K. Ranil D. de","family":"Silva","sequence":"additional","affiliation":[{"name":"Interdisciplinary Centre for Innovation in Biotechnology and Neuroscience, University of Sri Jayewardenepura, Nugegoda, Sri Lanka"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,11,13]]},"reference":[{"key":"bibr1-0972753120950069","unstructured":"World Bank 2014 [Internet], [cited April 4, 2019], https:\/\/www.worldbank.org\/en\/topic\/health\/brief\/poverty-health"},{"key":"bibr2-0972753120950069","first-page":"953","volume-title":"Genomics and health in the developing world","volume":"2012","author":"Dissanayake VHW."},{"key":"bibr3-0972753120950069","doi-asserted-by":"crossref","unstructured":"Sirisena ND, Dissanayake VHW. Genetics and genomic medicine in Sri Lanka. 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