{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T06:10:21Z","timestamp":1783923021981,"version":"3.55.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Annals of Neurosciences"],"published-print":{"date-parts":[[2026,7]]},"abstract":"\n Background<\/jats:title>\n Myotonic dystrophy Type 1 (DM1) is a multisystem genetic disorder characterised by progressive muscle weakness along with ocular, cardiac and endocrine abnormalities. However, detrusor underactivity manifesting as urinary retention is an under-recognised and rarely reported complication.<\/jats:p>\n <\/jats:sec>\n \n Purpose<\/jats:title>\n To highlight a case of urinary retention caused by detrusor muscle underactivity in a young female with classic features of DM1, highlighting the need for early recognition and management of this rare but significant manifestation.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n This case is of a 31-year-old female with urinary retention due to detrusor muscle underactivity, which is an under-recognised complication of DM1. The patient had classical features including grip myotonia, frontal balding, ptosis, intellectual impairment and early cataract changes. Uroflowmetry and significant post-void residual volume confirmed an atonic bladder. Elevated creatinine phosphokinase levels prompted electromyography, which demonstrated myotonic dive bomber discharges, and genetic testing identified pathogenic CTG trinucleotide repeat expansion in the myotonic dystrophy protein kinase (\n DMPK<\/jats:italic>\n ) gene.\n <\/jats:p>\n <\/jats:sec>\n \n Result<\/jats:title>\n The patient was treated initially with clean intermittent catheterisation and Bethanechol (muscarinic agonist), then switched to indwelling urinary catheterisation due to improper technique. However, the risk of recurrent urinary tract infections remains a concern. Carbamazepine improved grip myotonia.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n This case highlights the importance of the recognition of urinary retention as an important complication of DM1 and early recognition and treatment to prevent complications like recurrent urinary tract infections.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/09727531251409516","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T06:51:33Z","timestamp":1772088693000},"page":"335-339","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Fading Muscle and a Flaccid Bladder: Atonic Bladder in a Case of Myotonic Dystrophy\u2014A Case Report"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-7955-2615","authenticated-orcid":false,"given":"Preethi Yazhini","family":"Ravichandran","sequence":"first","affiliation":[{"name":"Department of General Medicine, SRM Medical College Hospital and Research Center, Kattankulathur, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalpana","family":"R","sequence":"additional","affiliation":[{"name":"Department of Neurology, SRM Medical College Hospital and Research Center, Kattankulathur, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnaswamy","family":"Madhavan","sequence":"additional","affiliation":[{"name":"Department of General Medicine, SRM Medical College Hospital and Research Center, Kattankulathur, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"key":"e_1_3_9_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90154-5"},{"key":"e_1_3_9_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20800"},{"issue":"2","key":"e_1_3_9_4_2","first-page":"131","article-title":"Epidemiological study of myotonic dystrophy: Description of signs and symptoms among 349 patients","volume":"26","author":"Mathieu J","year":"1999","unstructured":"Mathieu J, , Pr\u00e9vost C, , Gagnon C, . Epidemiological study of myotonic dystrophy: Description of signs and symptoms among 349 patients. Can J Neurol Sci 1999; 26(2): 131\u2013136.","journal-title":"Can J Neurol Sci"},{"key":"e_1_3_9_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa062800"},{"key":"e_1_3_9_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2008.158261"},{"key":"e_1_3_9_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurol.2016.08.003"},{"issue":"6","key":"e_1_3_9_8_2","first-page":"455","article-title":"Cognitive impairment in adult myotonic dystrophy Type 1: A longitudinal study","volume":"17","author":"Sansone V","year":"2007","unstructured":"Sansone V, , Gandossini S, , Cotelli M, . Cognitive impairment in adult myotonic dystrophy Type 1: A longitudinal study. Neuromuscul Disord 2007; 17(6): 455\u2013459.","journal-title":"Neuromuscul Disord"},{"key":"e_1_3_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(03)00220-0"},{"key":"e_1_3_9_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016349.2010.526188"},{"issue":"11","key":"e_1_3_9_11_2","article-title":"Prevalence of urinary incontinence and other pelvic floor disorders in women with myotonic dystrophy Type 1","volume":"33","author":"Fisette-Paulhus I","year":"2022","unstructured":"Fisette-Paulhus I, , Gagnon C, , Morin M, . Prevalence of urinary incontinence and other pelvic floor disorders in women with myotonic dystrophy Type 1. Neuromuscul Disord 2022; 33(11): 101088.","journal-title":"Neuromuscul Disord"},{"issue":"2","key":"e_1_3_9_12_2","first-page":"227","article-title":"Lower urinary tract and bowel dysfunction in patients with myotonic dystrophy","volume":"1","author":"Vohanka S","year":"2014","unstructured":"Vohanka S, , Bednarik J, , Hoskovcov\u00e1 M, . Lower urinary tract and bowel dysfunction in patients with myotonic dystrophy. J Neuromuscul Dis 2014; 1(2): 227\u2013235.","journal-title":"J Neuromuscul Dis"},{"key":"e_1_3_9_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/nau.1930110305"}],"container-title":["Annals of Neurosciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09727531251409516","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/09727531251409516","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/09727531251409516","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T05:33:56Z","timestamp":1783920836000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/09727531251409516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,25]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1177\/09727531251409516"],"URL":"https:\/\/doi.org\/10.1177\/09727531251409516","relation":{},"ISSN":["0972-7531","0976-3260"],"issn-type":[{"value":"0972-7531","type":"print"},{"value":"0976-3260","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,25]]}}}