{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T06:10:19Z","timestamp":1783923019277,"version":"3.55.0"},"reference-count":18,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:00:00Z","timestamp":1773878400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Annals of Neurosciences"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The bioenergetic therapy model combines holistic somatic therapy with psychotherapy, addressing both physical and emotional aspects of healing. In cases of long-standing treatment-resistant schizophrenia (TRS), which may persist for over two decades, finding effective therapeutic strategies remain a significant challenge. Despite numerous treatment options, no existing reports integrate somatosensory therapy with neuropsychopharmacological interventions for these complex cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To demonstrate the integration of bioenergetic therapy with neuropsychopharmacological interventions in managing long-standing treatment-resistant schizophrenic cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two cases of long-standing schizophrenia were illustrated for how we integrated somatosensory bioenergetics principles with neuropsychopharmacology. They had emotional and\/or physical abuse in addition to psychotic symptoms without any pre-morbid schizoid\/paranoid traits or psychiatric history of substance abuse, and presented to us with complaints of high sensitivity to rejection, persecutory delusions, third-person auditory hallucinations, irritability, episodic aggression, psychomotor retardation, disturbed sleep, and declining professional performance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A systematic cognitive deficit evaluation, slow building of clozapine (100 mg\/day), integration of somatosensory therapy, family system therapy model and cognitive enhancement therapy were integrated. This integration of somatosensory therapy with neuropsychopharmacological interventions led to a significant improvement over a four-week period. Notable recovery was observed in the experience of being touched for rebuilding maternal trust and developing a therapeutic rapport.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Integration of multiple system bioenergetic model in chronic TRS adds another novel way to its management which is an advanced extrapolation of the Bio-Psycho-Social model of schizophrenia. Bioenergetic analysis facilitated a unique somatic psychotherapy that combined cognitive feelings, somatic, and psychomotor functions. To our knowledge, this represents the first successful application of bioenergetic analytical integration in schizophrenia with marked behavioural resistance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09727531251409878","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T06:30:42Z","timestamp":1773988242000},"page":"340-344","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Integrating Bioenergetic Therapy Model with Neuropsychopharmacological Interventions in Long-standing Treatment-resistant Schizophrenia: Case Series and Review of Literature"],"prefix":"10.1177","volume":"33","author":[{"given":"Praveen","family":"Khairkar","sequence":"first","affiliation":[{"name":"Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divya","family":"Chadha","sequence":"additional","affiliation":[{"name":"Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwini","family":"Kamble","sequence":"additional","affiliation":[{"name":"Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-6554-9585","authenticated-orcid":false,"given":"Archish","family":"Khivsara","sequence":"additional","affiliation":[{"name":"Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-0581-3349","authenticated-orcid":false,"given":"Rohan","family":"Modi","sequence":"additional","affiliation":[{"name":"Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Khairkar","sequence":"additional","affiliation":[{"name":"Pacific Institute of Medical Sciences, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,19]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(15)00575-1"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0b013e318267b3cd"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/17432979.2019.1681514"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2011.09.003"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2017.05.024"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/neurosci4020012"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/10481885.2011.595337"},{"key":"e_1_3_6_9_2","first-page":"74","article-title":"The ever changing constancy of body psychotherapy","volume":"11","author":"Hilton R.","year":"2012","unstructured":"Hilton R. 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