{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T04:55:37Z","timestamp":1781844937983,"version":"3.54.5"},"reference-count":79,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T00:00:00Z","timestamp":1781395200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T00:00:00Z","timestamp":1781395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Annals of Neurosciences"],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Digital technology has rapidly transformed how people communicate, learn, and perform professional activities. While technological advancements have improved access to information, productivity, and global connectivity, excessive reliance on digital devices has raised concerns regarding cognitive and behavioral health. Emerging evidence suggests that prolonged screen exposure, constant multitasking, and dependence on digital aids may contribute to cognitive symptoms resembling dementia, including impaired attention, memory difficulties, reduced problem-solving ability, and emotional disengagement. This phenomenon, often described as \u201cvirtual dementia\u201d or \u201cdigital dementia,\u201d has become an area of growing scientific and public health interest.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Current evidence indicates that excessive digital technology use may alter neural circuits involved in cognition, particularly within the prefrontal cortex, hippocampus, and the Default Mode Network. These changes may manifest as digital amnesia, attentional fragmentation, mental fatigue, reduced social engagement, and emotional blunting. Adolescents and young adults appear especially vulnerable due to ongoing neurodevelopment, although many of these changes may be reversible with behavioral modification. Unlike neurodegenerative disorders such as Alzheimer\u2019s disease, virtual dementia is characterized by lifestyle-associated and potentially reversible cognitive dysfunction. At the same time, digital technologies also show therapeutic potential in cognitive monitoring, rehabilitation, and preventive interventions, highlighting their dual role in brain health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key Message<\/jats:title>\n                    <jats:p>Virtual dementia represents a potentially reversible form of technology-associated cognitive impairment driven by maladaptive digital behaviours. Promoting digital hygiene, mindful technology use, cognitive training, and responsible technology policies may help protect cognitive health. Future longitudinal and mechanistic studies are needed to establish diagnostic criteria, clarify long-term neurological effects, and develop evidence-based prevention and intervention strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/09727531261420601","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T05:36:36Z","timestamp":1781501796000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Virtual Dementia in the Digital Age: Neurocognitive Mechanisms, Behavioural Impact and Public Health Implications of Technology Overuse"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2707-2501","authenticated-orcid":false,"given":"Arunkumar","family":"Subramanian","sequence":"first","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, Faculty of Medical and Life Sciences, Sunway University, Selangor, Malaysia"},{"name":"Department of Pharmacology, Thanthai Roever College of Pharmacy, Perambalur, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R Aishwarya","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwin","family":"Ravichandran","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahendran","family":"Sekar","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Monash University Malaysia, Subang Jaya, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling Shing","family":"Wong","sequence":"additional","affiliation":[{"name":"Faculty of Health and Life Sciences, INTI International University, Nilai, Negeri Sembilan, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5690-9729","authenticated-orcid":false,"given":"Yashas","family":"Chandra","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Acharya and BM Reddy College of Pharmacy, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8050-424X","authenticated-orcid":false,"given":"Mariyammal","family":"R","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Thanthai Roever College of Pharmacy, Perambalur, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3240-0645","authenticated-orcid":false,"given":"Tamilanban","family":"T","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Medicine, MAHSA University, Bandar Saujana Putra, Selangor, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8695-446X","authenticated-orcid":false,"given":"Manasa","family":"K","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Pharmacy, MAHSA University, Bandar Saujana Putra, Selangor, Malaysia"},{"name":"Department of Pharmacology, MNR College of Pharmacy, Sangareddy, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinoth","family":"Kumarasamy","sequence":"additional","affiliation":[{"name":"Department of Parasitology and Medical Entomology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vetriselvan","family":"Subramaniyan","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, School of Pharmacy, Faculty of Medical and Life Sciences, Sunway University, Selangor, Malaysia"},{"name":"Global Research Cell, Dr. D. 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