{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T11:32:18Z","timestamp":1782473538184,"version":"3.54.5"},"reference-count":70,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asia Pac J Public Health"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:p>\n                    We conducted a systematic review research and meta-analysis to reveal the relationship between the risk of chronic diarrhea and Cryptosporidium infection in people living with HIV in Southeast Asia. We performed online peer-reviewed literature research from January 2005 to December 2017, which included PubMed, Science Direct, ProQuest, EBSCO, Cochrane, and Web of Science databases. Calculation of size effects in the meta-analysis was performed by STATA 13.0 software to estimate relative risks (RRs) with 95% confidence intervals (CIs) for any associations. Seven cross-sectional research articles were recruited in this study based on the inclusion and exclusion criteria. Our analysis revealed a significant relationship between cryptosporidiosis and the risk of chronic diarrhea in people living with HIV, with RR = 1.325; 95% CI = 1.157 to 1.517; and P &lt; .000. Our results suggested that cryptosporidiosis increases the risk of chronic diarrhea, and low CD4\n                    <jats:sup>+<\/jats:sup>\n                    lymphocyte cell counts aggravate the degree of diarrhea. Therefore, clinicians should be more aware in treating HIV-positive people, especially those with low CD4\n                    <jats:sup>+<\/jats:sup>\n                    cell counts, and we suggest that Cryptosporidium laboratory examinations be conducted immediately.\n                  <\/jats:p>","DOI":"10.1177\/1010539519895422","type":"journal-article","created":{"date-parts":[[2020,2,10]],"date-time":"2020-02-10T08:22:31Z","timestamp":1581322951000},"page":"8-18","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":30,"title":["<i>Cryptosporidium<\/i>\n                    Infection Increases the Risk for Chronic Diarrhea Among People Living With HIV in Southeast Asia: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0025-9405","authenticated-orcid":false,"given":"Wiwien S.","family":"Utami","sequence":"first","affiliation":[{"name":"Jember 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