{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T02:52:27Z","timestamp":1777431147476,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100003323","name":"Agence Nationale de Recherches sur le Sida et les H\u00e9patites Virales","doi-asserted-by":"publisher","award":["ANRS 12415"],"award-info":[{"award-number":["ANRS 12415"]}],"id":[{"id":"10.13039\/501100003323","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Asia Pac J Public Health"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>This study aimed to explore the perspectives of actors in human immunodeficiency virus (HIV) prevention concerning pre-exposure prophylaxis (PrEP) in Cambodia. Interviews with national-level policymakers and focus groups with service providers (health care workers and community-based organization [CBO] workers) providing care to key populations (KPs) were conducted in 2022. Actors viewed pre-exposure prophylaxis as an effective tool for reducing HIV transmission among KPs and were committed to its implementation. However, they were concerned about KPs\u2019 lack of protection against sexually transmitted infections other than HIV and about unintended pregnancies, as well as potential challenges to PrEP adherence and associated side effects. Key barriers to implementation included funding shortages, difficulties in reaching mobile KPs, and the need for further training for service providers. This study revealed the strong commitment to PrEP of actors in HIV prevention in Cambodia, and the need for community-centered approaches to ensure that sexual and reproductive health services best meet KPs\u2019 needs.<\/jats:p>","DOI":"10.1177\/10105395251414811","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T11:37:45Z","timestamp":1770205065000},"page":"44-54","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Perspectives of HIV Prevention Policymakers, Health Care Workers and Community Workers Concerning PrEP Implementation in Cambodia: The ANRS Quali-PrEP Study"],"prefix":"10.1177","volume":"38","author":[{"given":"Rothmony","family":"Eang","sequence":"first","affiliation":[{"name":"University of Health Sciences, Phnom Penh, Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Segeral","sequence":"additional","affiliation":[{"name":"HIV Unit, Infectious Diseases Department, Geneva University Hospital, Geneva, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4253-5534","authenticated-orcid":false,"given":"Camilla","family":"Oliveri","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, IRD, Inserm, Sciences Economiques &amp; Sociales de la Sant\u00e9 &amp; Traitement de l\u2019Information M\u00e9dicale, ISSPAM, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Mora","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, IRD, Inserm, Sciences Economiques &amp; Sociales de la Sant\u00e9 &amp; Traitement de l\u2019Information M\u00e9dicale, ISSPAM, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lerksmey","family":"Puth","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Phnom Penh, Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prom","family":"Sengrith","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Phnom Penh, Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilie","family":"Mosnier","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, IRD, Inserm, Sciences Economiques &amp; Sociales de la Sant\u00e9 &amp; Traitement de l\u2019Information M\u00e9dicale, ISSPAM, Marseille, France"},{"name":"Global Health Unit, University of Health Sciences, Phnom Penh, Cambodia"},{"name":"French Agency for Research on AIDS, Viral Hepatitis and Emerging Infectious diseases (ANRS-MIE), Phnom Penh, Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno","family":"Spire","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, IRD, Inserm, Sciences Economiques &amp; Sociales de la Sant\u00e9 &amp; Traitement de l\u2019Information M\u00e9dicale, ISSPAM, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vonthanak","family":"Saphonn","sequence":"additional","affiliation":[{"name":"University of Health Sciences, Phnom Penh, Cambodia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1615-4579","authenticated-orcid":false,"given":"Marion","family":"Fiorentino","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, IRD, Inserm, Sciences Economiques &amp; Sociales de la Sant\u00e9 &amp; Traitement de l\u2019Information M\u00e9dicale, ISSPAM, Marseille, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"UNAIDS. Cambodia. Published 2022. Accessed July 6 2023. https:\/\/www.unaids.org\/en\/regionscountries\/countries\/cambodia"},{"key":"e_1_3_3_3_2","unstructured":"National Center for HIV\/AIDS Dermatology and STD. Integrated HIV bio-behavioral surveillance survey (IBBS) among female entertainment workers in Cambodia 2022. Published 2022. Accessed March 16 2024. https:\/\/www.nchads.gov.kh\/wp-content\/uploads\/2022\/10\/FEW_IBBS_2022_DS_en.pdf"},{"key":"e_1_3_3_4_2","unstructured":"National Center for HIV\/AIDS Dermatology and STD. Integrated HIV bio-behavioral surveillance survey (IBBS) among men who have sex with men (MSM) and transgender women (TGW) in Cambodia 2023. Published 2023. Accessed March 16 2024. https:\/\/www.nchads.gov.kh\/wp-content\/uploads\/2023\/12\/MSM-TGW_IBBS-2023_ENG_V8.pdf"},{"key":"e_1_3_3_5_2","unstructured":"UNAIDS Asia-Pacific. Despite impressive treatment results Cambodia\u2019s HIV response must address inequalities affecting children and young key populations. Published April 5 2023. Accessed November 10 2025. https:\/\/unaids-ap.org\/2023\/04\/05\/despite-impressive-treatment-results-cambodias-hiv-response-must-addressinequalities-affecting-children-and-young-key-populations\/"},{"key":"e_1_3_3_6_2","volume-title":"Consolidated Guidelines on HIV, Viral Hepatitis and STI Prevention, Diagnosis, Treatment and Care for Key Populations","author":"World Health Organization","year":"2022","unstructured":"World Health Organization. Consolidated Guidelines on HIV, Viral Hepatitis and STI Prevention, Diagnosis, Treatment and Care for Key Populations. World Health Organization; 2022."},{"key":"e_1_3_3_7_2","unstructured":"National Center for HIV\/AIDS Dermatology and STD. Accessed February 14 2025. https:\/\/www.nchads.gov.kh\/en\/annual_report\/"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2012-001234"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-011-9894-1"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1080\/09540121.2024.2308029"},{"key":"e_1_3_3_11_2","unstructured":"Fiorentino M. Qualitative assessment about PrEP acceptability in key-populations and conditions required for community-based PrEP implementation in Cambodia (clinicaltrials.gov ID: NCT05091489). Published 2023. Accessed January 1 2024. https:\/\/clinicaltrials.gov\/study\/NCT05091489"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9566.ep11347023"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1191\/1478088706qp063oa"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1089\/apc.2019.0189"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000002750"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-020-03110-x"},{"key":"e_1_3_3_17_2","doi-asserted-by":"crossref","unstructured":"Quaife M Macgregor LW Ong J et al. Risk compensation and STI incidence in PrEP programmes: latest evidence and research gaps. Lancet HIV. 2019;7:e222-e223. Accessed December 4 2024. https:\/\/research-information.bris.ac.uk\/files\/211073864\/Risk_compensation_clean_2.pdf","DOI":"10.1016\/S2352-3018(19)30333-9"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/jacamr\/dlae053"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30725-9"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2211934"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-018-1768-3"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(22)00123-0"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(23)00197-8"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-021-12235-0"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkac229"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2022.11.246"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.26107"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac752"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2407001"},{"key":"e_1_3_3_30_2","unstructured":"PrEP PURPOSE-2 twice-yearly Gilead Glasgow press release. Accessed March 3 2025. https:\/\/www.natap.org\/2024\/Glasgow\/GLASGOW_37.htm"},{"key":"e_1_3_3_31_2","unstructured":"Gilead. Lenacapavir license agreement. Accessed March 3 2025. https:\/\/www.gilead.com\/-\/media\/gileadcorpredesign\/pdf\/Other\/LEN-VL.pdf"}],"container-title":["Asia Pacific Journal of Public Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10105395251414811","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10105395251414811","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10105395251414811","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:44:19Z","timestamp":1777376659000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10105395251414811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1177\/10105395251414811"],"URL":"https:\/\/doi.org\/10.1177\/10105395251414811","relation":{},"ISSN":["1010-5395","1941-2479"],"issn-type":[{"value":"1010-5395","type":"print"},{"value":"1941-2479","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]}}}