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One hundred ninety-five women were recruited from two health care facilities in the Thai Binh Province, Northern Vietnam. Depressive symptoms were assessed using the Edinburgh Postnatal Depression Scale (EPDS) at three time points: before GDM diagnosis (24-28 weeks), at 36 weeks\u2019 gestation, and 12 weeks postpartum. Mixed-effects linear models guided by a directed acyclic graph were used to examine associations. The EPDS scores remained stable during pregnancy but were significantly lower postpartum than at prediagnosis (mean difference [MD]\u2009=\u2009\u22122.94; 95% CI, \u22123.59 to \u22122.29) and 36 weeks\u2019 gestation (MD\u2009=\u2009\u22123.16; 95% CI, \u22123.72 to \u22122.61). Differences in EPDS trajectories were observed across sociodemographic characteristics, with women who were not living with their spouse\/partner or were divorced\/separated showing the greatest reductions in EPDS scores. Maternal mental health in GDM follows a nonlinear trajectory. Integrated GDM care should include mental health screening and social support.<\/jats:p>","DOI":"10.1177\/10105395261474608","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T10:11:36Z","timestamp":1786356696000},"page":"483-490","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Depressive Symptom Trajectories in Gestational Diabetes Mellitus: A Longitudinal Study From Northern Vietnam (VALID II)"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4389-5225","authenticated-orcid":false,"given":"Ai th\u1ecb","family":"Nguyen","sequence":"first","affiliation":[{"name":"Faculty of Public Health, Thai Binh University of Medicine and Pharmacy, Hung Yen, Vietnam"},{"name":"Ha Noi Medical University, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dang Kien","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Thai Binh University of Medicine and Pharmacy, Hung Yen, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minh Hieu","family":"Le","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Thai Binh University of Medicine and Pharmacy, Hung Yen, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan Wolf","family":"Meyrowitsch","sequence":"additional","affiliation":[{"name":"Global Health Section, Department of Public Health, University of Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ib Christian","family":"Bygbjerg","sequence":"additional","affiliation":[{"name":"Global Health Section, Department of Public Health, University of Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thuy Hanh Thi","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Ha Noi Medical University, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina Anne","family":"Vinter","sequence":"additional","affiliation":[{"name":"Research Unit for Gynaecology and Obstetrics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark"},{"name":"Department of Gynaecology and Obstetrics, Odense University Hospital, Denmark"},{"name":"Steno Diabetes Center Odense, Odense University Hospital, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunsen","family":"Wu","sequence":"additional","affiliation":[{"name":"Research Unit for Gynaecology and Obstetrics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark"},{"name":"Department of Gynaecology and Obstetrics, Odense University Hospital, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gammeltoft","family":"Tine","sequence":"additional","affiliation":[{"name":"Department of Anthropology, University of Copenhagen, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vibeke","family":"Rasch","sequence":"additional","affiliation":[{"name":"Research Unit for Gynaecology and Obstetrics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark"},{"name":"Department of Gynaecology and Obstetrics, Odense University Hospital, Denmark"},{"name":"Centre for Global Health, Department of Clinical Research, University of Southern Denmark, Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0851-6760","authenticated-orcid":false,"given":"Ditte S\u00f8ndergaard","family":"Linde","sequence":"additional","affiliation":[{"name":"Research Unit for Gynaecology and Obstetrics, Department of Clinical Research, University of Southern Denmark, Odense, Denmark"},{"name":"Department of Gynaecology and Obstetrics, Odense University Hospital, Denmark"},{"name":"Centre for Global Health, Department of Clinical Research, University of Southern Denmark, Odense, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,10]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2018.02.023"},{"key":"e_1_3_3_3_2","unstructured":"Rao AP Khatib MN Thangavelu L et al. 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