{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:14:00Z","timestamp":1777929240033,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Major Project of NSFC","award":["81991514"],"award-info":[{"award-number":["81991514"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82002294"],"award-info":[{"award-number":["82002294"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82272492"],"award-info":[{"award-number":["82272492"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Key Research and Development Project","award":["2021YFA1201404"],"award-info":[{"award-number":["2021YFA1201404"]}]},{"name":"Jiangsu Province Medical Innovation Center of Orthopedic Surgery","award":["CXZX202214"],"award-info":[{"award-number":["CXZX202214"]}]},{"name":"Jiangsu Provincial Key Medical Center Foundation"},{"name":"Jiangsu Provincial Medical Outstanding Talent Foundation"},{"name":"Jiangsu Provincial Medical Youth Talent Foundation and Jiangsu Provincial Key Medical Talent Foundation"},{"name":"The Fundamental Research Funds for the Central Universities","award":["14380493"],"award-info":[{"award-number":["14380493"]}]},{"name":"The Fundamental Research Funds for the Central Universities","award":["14380494"],"award-info":[{"award-number":["14380494"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthop Surg (Hong Kong)"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Total knee arthroplasty is the most effective treatment for advanced-stage knee arthritis, and the majority of knee prostheses are made of metal. Nevertheless, metal prostheses still have several problems. The objective of this study is to introduce new metal-free knee prostheses made of polyether-ether-ketone (PEEK) and to compare their cement bond strength with metal prostheses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Twelve sets of knee prostheses were divided into four groups (unloaded PEEK, unloaded Metal, 10 million cycles (MC) PEEK, 10\u00a0MC Metal, N = 3 each), and then attached to composite bones using bone cement. Both the 10\u00a0MC PEEK and 10\u00a0MC Metal groups were subjected to dynamic gait simulations of 10\u00a0MC, whereas the other two sets were not. Afterwards, a pull-off strength test was performed on the femoral prostheses and a shear strength test was performed on the tibial prostheses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No apparent cracks were observed in the bone cement after subjecting the PEEK and Metal groups to 10 million cycles of dynamic simulation. No statistically significant differences were observed ( p &gt; .05) in the strength tests for unloaded PEEK vs. unloaded Metal, 10\u00a0MC PEEK vs.10\u00a0MC Metal in the femoral pull-off test, and for unloaded PEEK vs. unloaded Metal in the tibial shear test. The shear strength of 10\u00a0MC PEEK was significantly lower ( p &lt; .05) compared to that of 10\u00a0MC Metal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>By comparing the force analysis of previous investigations on knee prostheses with the failure pattern observed in the PEEK knee prosthesis of this study, which replicates that of the metal prosthesis. We believe that the combination of the peek knee prosthesis with bone cement is reliable. We anticipate that metal-free PEEK knee prostheses will find application in Total Knee Arthroplasty (TKA) in the future, thereby benefiting patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10225536231217537","type":"journal-article","created":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T03:32:15Z","timestamp":1700796735000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Bond strength of metal-free polyether-ether-ketone knee prostheses compared to metal knee prostheses with bone cement: A preliminary in vitro study"],"prefix":"10.1177","volume":"31","author":[{"given":"Dengxian","family":"Wu","sequence":"first","affiliation":[{"name":"Division of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, PR China."},{"name":"State Key Laboratory 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Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, PR China."},{"name":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, Jiangsu, PR China."},{"name":"Branch of National Clinical Research Center for Orthopedics, Sports Medicine and Rehabilitation, PR China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Division of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, PR China."},{"name":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, Jiangsu, PR China."},{"name":"Branch of National Clinical Research Center for Orthopedics, Sports Medicine and Rehabilitation, PR China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donggui","family":"Zheng","sequence":"additional","affiliation":[{"name":"Suzhou SinoMed Biomaterials Co., Ltd, Suzhou, Jiangsu, PR China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Jiang","sequence":"additional","affiliation":[{"name":"Division of Sports Medicine and Adult Reconstructive Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, Jiangsu, PR China."},{"name":"State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, Jiangsu, PR China."},{"name":"Branch of National Clinical Research Center for Orthopedics, Sports Medicine and Rehabilitation, PR 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