{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T10:55:09Z","timestamp":1782298509034,"version":"3.54.5"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Orthop Surg (Hong Kong)"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To analyze the effect of artificial dermis technology combined with full-thickness skin graft coverage in the treatment of foot and ankle wound defects in the elderly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 90 elderly patients treated for foot and ankle wound defects from January 2021 to December 2022 were selected as the study subjects and were divided into a control group of 40 cases and a study group of 50 cases according to the random number table method. The control group was treated with retrograde saphenous nerve flap transplantation, while the study group was treated with artificial dermis technology combined with full-thickness skin graft coverage. The therapeutic effect of artificial dermis technology combined with full-thickness skin graft coverage was observed. The ankle function, pain level, postoperative wound recovery, relevant indicators, and postoperative wound complications were compared between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At 2 and 4 weeks after treatment, the ankle function of both groups was higher than before treatment, and the ankle function of the study group was higher than that of the control group (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; .05). At 2 and 4 weeks after treatment, the VAS and PPI scores of both groups were lower than before treatment, and the VAS and PPI scores of the study group were lower than those of the control group (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; .05). Compared with the control group, the study group had lower color, thickness, vascular distribution, and softness, as well as shorter surgical preparation time, hospital stay, antibiotic use, and fewer dressing changes. The overall incidence of flap edema, wound infection, and total wound infection was lower in the study group (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      &lt; .05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The use of artificial dermis technology combined with full-thickness skin graft coverage in the treatment of foot and ankle wound defects in the elderly helps to improve ankle joint function, reduce the degree of pain, and results in better postoperative wound recovery and a lower complication rate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10225536251324055","type":"journal-article","created":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T03:20:58Z","timestamp":1742613658000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Observation of the effect of artificial dermis technology combined with full-thickness skin graft coverage in the treatment of foot and ankle wound defects in the elderly"],"prefix":"10.1177","volume":"33","author":[{"given":"Qiang","family":"Xie","sequence":"first","affiliation":[{"name":"The Affiliated Hospital of Chengde Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Hao","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Chengde Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Kong","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Chengde Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei","family":"Wang","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Chengde Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,3,22]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/os.13046"},{"issue":"3","key":"e_1_3_3_3_2","doi-asserted-by":"crossref","first-page":"1009714","DOI":"10.3389\/fendo.2022.1009714","article-title":"Application of the distally based sural neurocutaneous flaps in the management of foot and ankle defects in patients with diabetic foot","volume":"13","author":"Dai J","year":"2022","unstructured":"Dai J, Zhou Y, Mei S, et al. Application of the distally based sural neurocutaneous flaps in the management of foot and ankle defects in patients with diabetic foot. Front Endocrinol 2022; 13(3): 1009714.","journal-title":"Front Endocrinol"},{"issue":"2","key":"e_1_3_3_4_2","first-page":"412","article-title":"Reconstruction of foot and ankle defects using free lateral arm flap: a retrospective review of its versatile application","volume":"2021","author":"Kim JH","year":"2021","unstructured":"Kim JH, Yoon T, Park JK, et al. Reconstruction of foot and ankle defects using free lateral arm flap: a retrospective review of its versatile application. BioMed Res Int 2021; 2021(2): 412\u2013427.","journal-title":"BioMed Res Int"},{"issue":"7","key":"e_1_3_3_5_2","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1080\/08941939.2018.1536177","article-title":"Pelnac\u00ae artificial dermis assisted by VSD for treatment of complex wound with bone\/tendon exposed at the foot and ankle, A prospective study","volume":"33","author":"Lv Z","year":"2020","unstructured":"Lv Z, Wang Q, Jia R, et al. Pelnac\u00ae artificial dermis assisted by VSD for treatment of complex wound with bone\/tendon exposed at the foot and ankle, A prospective study. J Invest Surg 2020; 33(7): 636\u2013641.","journal-title":"J Invest Surg"},{"issue":"11","key":"e_1_3_3_6_2","doi-asserted-by":"crossref","first-page":"3843","DOI":"10.1016\/j.injury.2022.08.068","article-title":"Comparison of \u201ccomplications\u201d and functional outcome of anterolateral thigh flap and sural neurofasciocutaneus flap for foot and ankle reconstruction: a single center cohort study","volume":"53","author":"Du S","year":"2022","unstructured":"Du S, Wei S, Zhang H, et al. Comparison of \u201ccomplications\u201d and functional outcome of anterolateral thigh flap and sural neurofasciocutaneus flap for foot and ankle reconstruction: a single center cohort study. Injury 2022; 53(11): 3843\u20133848.","journal-title":"Injury"},{"issue":"3","key":"e_1_3_3_7_2","first-page":"225","article-title":"Expert consensus on clinical Diagnosis and treatment of post-traumatic multiple organ dysfunction Syndrome","volume":"34","author":"Chinese Society of Research Hospitals, Shock and Sepsis Professional Committee, Chinese People\u2019s Liberation Army Trauma and Shock Professional Committee","year":"2022","unstructured":"Chinese Society of Research Hospitals, Shock and Sepsis Professional Committee, Chinese People\u2019s Liberation Army Trauma and Shock Professional Committee. Expert consensus on clinical Diagnosis and treatment of post-traumatic multiple organ dysfunction Syndrome. Chinese Journal of Critical Care Medicine 2022; 34(3): 225\u2013238.","journal-title":"Chinese Journal of Critical Care Medicine"},{"issue":"4","key":"e_1_3_3_8_2","first-page":"153","article-title":"Artificial dermis and autologous platelet-rich plasma for treatment of refractory wounds: a clinical study","volume":"27","author":"Lv Y","year":"2021","unstructured":"Lv Y, Yang Z, Chen Z, et al. Artificial dermis and autologous platelet-rich plasma for treatment of refractory wounds: a clinical study. Int J Low Extrem Wounds 2021; 27(4): 153\u2013210.","journal-title":"Int J Low Extrem Wounds"},{"issue":"2","key":"e_1_3_3_9_2","first-page":"120","article-title":"Clinical application of artificial dermis and autologous skin in repairing skin and soft tissue defects of hands and feet with bone exposure injuries","volume":"2021","author":"Li C","year":"2021","unstructured":"Li C, Song W, Lei Y, et al. Clinical application of artificial dermis and autologous skin in repairing skin and soft tissue defects of hands and feet with bone exposure injuries. Evid Based Complement Alternat Med 2021; 2021(2): 120\u2013216.","journal-title":"Evid Based Complement Alternat Med"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hansur.2022.02.012"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000024367"},{"issue":"2","key":"e_1_3_3_12_2","first-page":"91","article-title":"Clinical efficacy of double-layer artificial dermis combined with autologous skin graft transplantation for skin and soft tissue defects of the limbs","volume":"38","author":"Yang F","year":"2022","unstructured":"Yang F, Zhang B, Hou S, et al. Clinical efficacy of double-layer artificial dermis combined with autologous skin graft transplantation for skin and soft tissue defects of the limbs. Chinese Journal of Hand Surgery 2022; 38(2): 91\u201395.","journal-title":"Chinese Journal of Hand Surgery"},{"issue":"6","key":"e_1_3_3_13_2","first-page":"701","article-title":"Efficacy analysis of distal pedicle neurotrophic vascular flap for repairing postoperative residual wounds of malignant tumors in the foot and ankle","volume":"17","author":"Wang H","year":"2019","unstructured":"Wang H, Yang C, Lu D, et al. Efficacy analysis of distal pedicle neurotrophic vascular flap for repairing postoperative residual wounds of malignant tumors in the foot and ankle. Cancer Progress 2019; 17(6): 701\u2013703.","journal-title":"Cancer Progress"},{"issue":"11","key":"e_1_3_3_14_2","first-page":"1390","article-title":"Clinical application of chitosan propolis combined with autologous platelet-rich plasma composite material in non-acute infected wounds in orthopedics","volume":"38","author":"Xing T","year":"2022","unstructured":"Xing T, Zhang Y, Qian C, et al. Clinical application of chitosan propolis combined with autologous platelet-rich plasma composite material in non-acute infected wounds in orthopedics. Journal of Practical Medicine 2022; 38(11): 1390\u20131394.","journal-title":"Journal of Practical Medicine"},{"issue":"20","key":"e_1_3_3_15_2","first-page":"2561","article-title":"Efficacy of local oxygen therapy combined with recombinant bovine basic fibroblast growth factor and negative pressure drainage technology in chronic refractory wounds","volume":"38","author":"Bai Z","year":"2022","unstructured":"Bai Z, Wang H, Zhang L, et al. Efficacy of local oxygen therapy combined with recombinant bovine basic fibroblast growth factor and negative pressure drainage technology in chronic refractory wounds. Journal of Practical Medicine 2022; 38(20): 2561\u20132567.","journal-title":"Journal of Practical Medicine"},{"issue":"5","key":"e_1_3_3_16_2","first-page":"399","article-title":"Clinical study of decellularized allogeneic dermis combined with autologous split-thickness skin graft for repairing non-weight-bearing area wounds in the foot and ankle","volume":"17","author":"Ren Z","year":"2022","unstructured":"Ren Z, Cai W, Zhang Y, et al. Clinical study of decellularized allogeneic dermis combined with autologous split-thickness skin graft for repairing non-weight-bearing area wounds in the foot and ankle. Chinese Journal of Trauma and Repair (Electronic Edition) 2022; 17(5): 399\u2013404.","journal-title":"Chinese Journal of Trauma and Repair (Electronic Edition)"},{"issue":"1","key":"e_1_3_3_17_2","first-page":"87","article-title":"Anterolateral tibial artery perforator propeller flap relay posterior tibial artery terminal perforator propeller flap for repairing foot and ankle wounds","volume":"34","author":"Wang W","year":"2020","unstructured":"Wang W, Junming L, Dai P, et al. Anterolateral tibial artery perforator propeller flap relay posterior tibial artery terminal perforator propeller flap for repairing foot and ankle wounds. Chin J Reparative Reconstr Surg 2020; 34(1): 87\u201391.","journal-title":"Chin J Reparative Reconstr Surg"}],"container-title":["Journal of Orthopaedic Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10225536251324055","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10225536251324055","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10225536251324055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:31:55Z","timestamp":1777678315000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10225536251324055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1177\/10225536251324055"],"URL":"https:\/\/doi.org\/10.1177\/10225536251324055","relation":{},"ISSN":["1022-5536","2309-4990"],"issn-type":[{"value":"1022-5536","type":"print"},{"value":"2309-4990","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"article-number":"10225536251324055"}}