{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:22:02Z","timestamp":1777432922252,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,1,2]],"date-time":"2020-01-02T00:00:00Z","timestamp":1577923200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Australas Psychiatry"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Domestic family violence (FV) is a serious problem with serious impacts on mental health of victims. One such impact is post-traumatic stress disorder (PTSD), and it can be resistant to treatment (treatment-resistant or TR). This article offers novel treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Two treatment resistant case studies are described where adjunctive treatment with brexpiprazole was commenced. Possible theoretical considerations are presented to explain improvement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Adjunctive treatment with brexpiprazole was associated with significant improvement in FV subjective and objective measures, with enhanced response to trauma therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Brexpiprazole improved complex post traumatic stress disorder in FV victims and needs further evaluation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1039856219889303","type":"journal-article","created":{"date-parts":[[2020,1,3]],"date-time":"2020-01-03T00:22:13Z","timestamp":1578010933000},"page":"264-266","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Adjunctive therapy with brexpiprazole improves treatment resistant complex post traumatic stress disorder in domestic family violence victims"],"prefix":"10.1177","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8385-1040","authenticated-orcid":false,"given":"Manjula","family":"O\u2019Connor","sequence":"first","affiliation":[{"name":"Department of Psychiatry, The University of Melbourne, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,1,2]]},"reference":[{"key":"bibr1-1039856219889303","volume-title":"Preventing intimate partner and sexual violence against women and taking actions and generating evidence","author":"World Health Organization (WHO), London School of Hygiene and Tropical Medicine","year":"2010"},{"key":"bibr2-1039856219889303","unstructured":"Australian Bureau of Statistics. http:\/\/www.abs.gov.au\/ausstats\/abs@.nsf\/Lookup\/by%20Subject\/4510.0~2017~Main%20Features~Victims%20of%20Family%20and%20Domestic%20Violence%20Related%20Offences~6 (2018, accessed 5 June 2019)."},{"key":"bibr3-1039856219889303","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0051740"},{"key":"bibr4-1039856219889303","doi-asserted-by":"publisher","DOI":"10.1177\/1039856217737884"},{"key":"bibr5-1039856219889303","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.1098"},{"key":"bibr6-1039856219889303","unstructured":"White Ribbon Australia. Domestic violence statistics. https:\/\/www.whiteribbon.org.au\/understand-domestic-violence\/facts-violence-women\/domestic-violence-statistics\/ (accessed 4 July 2019)."},{"key":"bibr7-1039856219889303","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"bibr8-1039856219889303","doi-asserted-by":"publisher","DOI":"10.3390\/bs4040511"},{"key":"bibr9-1039856219889303","doi-asserted-by":"publisher","DOI":"10.3390\/jcm5120117"},{"key":"bibr10-1039856219889303","first-page":"99","volume":"8","author":"Khazaie H","year":"2016","journal-title":"J Inj Violence Res"},{"key":"bibr11-1039856219889303","doi-asserted-by":"publisher","DOI":"10.1177\/1039856217732473"},{"key":"bibr12-1039856219889303","unstructured":"Otsuka Pharmaceutical Co., Ltd. Otsuka and Lundbeck report positive phase II data for the combination treatment of brexpiprazole and sertraline for the treatment of Post-Traumatic Stress Disorder (PTSD). 30 November 2018."},{"key":"bibr13-1039856219889303","unstructured":"Product information AusPAR Rexulti Brexpiprazole Lundbeck Australia Pty Ltd. https:\/\/www.tga.gov.au\/sites\/default\/files\/auspar-brexpiprazole-180924-pi.pdf (accessed 6 December 2019)."},{"key":"bibr14-1039856219889303","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2017.11.017"},{"key":"bibr15-1039856219889303","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(93)90302-T"},{"key":"bibr16-1039856219889303","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.1.13"},{"key":"bibr17-1039856219889303","unstructured":"World Health Organization. International Classification of Diseases for Mortality and Morbidity Statistics Eleventh Revision. https:\/\/icd.who.int\/icd11refguide\/en\/index.html (2019, accessed 6 December 2019)."}],"container-title":["Australasian Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1039856219889303","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1039856219889303","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1039856219889303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:50:00Z","timestamp":1777377000000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1039856219889303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,2]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1177\/1039856219889303"],"URL":"https:\/\/doi.org\/10.1177\/1039856219889303","relation":{},"ISSN":["1039-8562","1440-1665"],"issn-type":[{"value":"1039-8562","type":"print"},{"value":"1440-1665","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,2]]}}}