{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T13:46:10Z","timestamp":1793108770998,"version":"4.5.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Janssen-Cilag Pty Ltd Australia"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Australas Psychiatry"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine patient characteristics, persistence and adherence to treatment associated with use of second-generation antipsychotic long-acting injectable (SGA LAI) medications in the Australian real-world setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>Five SGA LAIs were compared using a retrospective 10% sample of prescriptions in Australian Pharmaceutical Benefits Scheme (PBS) data: paliperidone palmitate 1-monthly (PP1M), paliperidone palmitate 3-monthly (PP3M), aripiprazole monohydrate (ARI), risperidone (RLAI) and olanzapine pamoate (OLAI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients in the PP3M cohort were more persistent with treatment ( p &lt; 0.001). Median months of persistence: PP3M (36\u00a0months); ARI (18\u00a0months); PP1M (11\u00a0months); OLAI (8\u00a0months); RLAI (4\u00a0months). Patients in the PP3M cohort were more adherent to treatment ( p &lt; 0.001): PP3M (78%); ARI (51%); PP1M (46%); OLAI (35%); RLAI (33%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients on PP3M treatment showed comparatively longer persistence and better adherence. Treatments for schizophrenia with longer dosing intervals may provide patients with symptomatic stability that could allow for reduced hospitalisations\/relapse and increased focus on functional recovery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10398562221142453","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T07:11:37Z","timestamp":1670397097000},"page":"76-81","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Persistence and adherence to second-generation antipsychotic long-acting injectable medications for schizophrenia: A comparative study in the Australian context"],"prefix":"10.1177","volume":"31","author":[{"given":"Nagesh","family":"Pai","sequence":"first","affiliation":[{"name":"University of Wollongong, Wollongong, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew B","family":"McGeachie","sequence":"additional","affiliation":[{"name":"Janssen Australia and New Zealand, Macquarie Park, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Puig","sequence":"additional","affiliation":[{"name":"Janssen Australia and New Zealand, Macquarie Park, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom H-W","family":"Huang","sequence":"additional","affiliation":[{"name":"Janssen Australia and New Zealand, Macquarie Park, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prachi","family":"Brahmbhatt","sequence":"additional","affiliation":[{"name":"Royal North Shore Hospital, St. Leonards, NSW, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,12,7]]},"reference":[{"key":"bibr1-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1177\/1039856220928867"},{"key":"bibr2-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(21)00039-0"},{"key":"bibr3-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-022-03755-z"},{"key":"bibr4-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1097\/00131746-200701000-00003"},{"key":"bibr5-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1177\/2045125317721874"},{"key":"bibr6-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2019.1615927"},{"key":"bibr7-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1177\/2045125320926347"},{"key":"bibr8-10398562221142453","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S286654"},{"key":"bibr9-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2020.20071120"},{"key":"bibr10-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1097\/01.jcp.0000185423.15891.02"},{"key":"bibr11-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2019.1571295"},{"key":"bibr12-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.8810"},{"key":"bibr13-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1002\/hup.2763"},{"key":"bibr14-10398562221142453","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-020-02661-6"},{"key":"bibr15-10398562221142453","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.IN18031AH1C"}],"container-title":["Australasian Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10398562221142453","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10398562221142453","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10398562221142453","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T11:51:48Z","timestamp":1777377108000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10398562221142453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12,7]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1177\/10398562221142453"],"URL":"https:\/\/doi.org\/10.1177\/10398562221142453","relation":{},"ISSN":["1039-8562","1440-1665"],"issn-type":[{"value":"1039-8562","type":"print"},{"value":"1440-1665","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,12,7]]}}}