{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:39:12Z","timestamp":1777433952945,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T00:00:00Z","timestamp":1704153600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Australas Psychiatry"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study examined the rates and persistence of clozapine-induced tachycardia and heart-rate differences in patients treated with \u03b2-blockers in the largest sample of patients with a psychotic disorder to date.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>An audit of medical files for 101 patients who attended a clozapine community clinic and analysis of monthly measurements of resting heart rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>51% met the clinical criteria for tachycardia. Heart rates were stable over time. \u03b2-blockers were associated with small but significant reductions in heart rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The cardiovascular risks of clozapine are often overlooked. \u03b2-blockers are useful in lowering heart rates but they may be insufficient to reduce cardiac risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10398562231224156","type":"journal-article","created":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T08:35:44Z","timestamp":1704184544000},"page":"84-88","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Clozapine-related tachycardia: A conundrum to identify and treat"],"prefix":"10.1177","volume":"32","author":[{"given":"Dermot","family":"Brennan","sequence":"first","affiliation":[{"name":"Armadale Health Service, East Metropolitan Health Service, Armadale, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sweta","family":"Lal","sequence":"additional","affiliation":[{"name":"Armadale Health Service, East Metropolitan Health Service, Armadale, WA, Australia"},{"name":"Peel and Rockingham Kwinana (PaRK) Mental Health Service, South Metropolitan Health Service, Rockingham, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frans","family":"Hugo","sequence":"additional","affiliation":[{"name":"Armadale Health Service, East Metropolitan Health Service, Armadale, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5570-2040","authenticated-orcid":false,"given":"Flavie","family":"Waters","sequence":"additional","affiliation":[{"name":"School of Psychological Sciences, The University of Western Australia, Perth, WA, Australia"},{"name":"Black Swan Health, Headspace Youth Early Psychosis Program, Perth, WA, Australia"},{"name":"North Metropolitan Health Service, Clinical Research Centre, Mount Claremont, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon","family":"Shymko","sequence":"additional","affiliation":[{"name":"Peel and Rockingham Kwinana (PaRK) Mental Health Service, South Metropolitan Health Service, Rockingham, WA, Australia"},{"name":"Black Swan Health, Headspace Youth Early Psychosis Program, Perth, WA, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,1,2]]},"reference":[{"key":"bibr1-10398562231224156","first-page":"38","volume":"59","author":"Lieberman JA","year":"1998","journal-title":"J Clin Psychiatr"},{"key":"bibr2-10398562231224156","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.163.4.600"},{"key":"bibr3-10398562231224156","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/17.2.247"},{"key":"bibr4-10398562231224156","doi-asserted-by":"publisher","DOI":"10.1097\/YIC.0000000000000169"},{"key":"bibr5-10398562231224156","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-312251"},{"key":"bibr6-10398562231224156","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)10385-4"},{"key":"bibr7-10398562231224156","unstructured":"DoH W. 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