{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T03:53:14Z","timestamp":1791604394573,"version":"4.3.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T00:00:00Z","timestamp":1776038400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Australas Psychiatry"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study analysed antipsychotic prescribing patterns at discharge from an acute Tasmanian MHIU, and evaluated prescribing practice alignment with RANZCP clinical practice guidelines (CPG) for schizophrenia and BPAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Descriptive cross-sectional analysis of discharge prescriptions was conducted for 202 patients extracted from routinely collected data. Diagnoses, prescribed antipsychotics, and doses (converted to olanzapine equivalents) were reviewed. Polypharmacy, as well as the use of depot and PRN doses, were also analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 66% of patients were prescribed antipsychotics at discharge, with 33% of this group receiving polypharmacy. Schizophrenia was the most common indication (35%), followed by off-label prescriptions (34%) and mood disorders (20%). Quetiapine IR and olanzapine were the most prescribed, with high rates of off-label use and polypharmacy. In around 10% of patients, doses exceeded 20\u00a0mg\/day olanzapine equivalents. Depot formulations were prescribed to 24% of patients, with aripiprazole being most common. Schizophrenia spectrum diagnoses were significantly associated with polypharmacy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study highlights high rates of antipsychotic off-label prescribing and polypharmacy. The findings underscore the need for individualized prescribing, enhanced monitoring, and regular medication reviews. They also raise questions about the applicability of CPGs. Further research should investigate factors influencing off-label prescribing and strategies for safer prescribing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10398562261441506","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T10:28:54Z","timestamp":1776076134000},"page":"498-505","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Antipsychotic prescribing patterns in a Tasmanian mental health inpatient unit (MHIU): Primary findings and comparison with RANZCP guidelines for schizophrenia and bipolar affective disorder (BPAD)"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0914-5316","authenticated-orcid":false,"given":"Jie Ming","family":"Joshua Yeoh","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Royal Hobart Hospital"},{"name":", Tasmanian Health Service"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1646-7601","authenticated-orcid":false,"given":"Antonio","family":"Mendoza Diaz","sequence":"additional","affiliation":[{"name":"Tasmanian Centre for Mental Health Service Innovation, Tasmanian Health Service"},{"name":"University of New South Wales"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1656-4766","authenticated-orcid":false,"given":"Sharad","family":"Tamrakar","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Royal Hobart Hospital"},{"name":", Tasmanian Health Service"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnob","family":"Chakraborti","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Royal Hobart Hospital"},{"name":", Tasmanian Health Service"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0486-7092","authenticated-orcid":false,"given":"Alexandra","family":"Blackfield","sequence":"additional","affiliation":[{"name":"Pharmacy Department, Royal Hobart Hospital"},{"name":", Tasmanian Health Service"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3075-1580","authenticated-orcid":false,"given":"David","family":"Castle","sequence":"additional","affiliation":[{"name":"Tasmanian Centre for Mental Health Service Innovation, Tasmanian Health Service"},{"name":"University of Tasmania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,13]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-021-03374-0"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/19585969.2025.2449833"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41386-021-01163-7"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145712000399"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(24)00314-6"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/0004867412450471"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/10398562241283156"},{"key":"e_1_3_6_9_2","volume-title":"Antipsychotic dose equivalents","author":"Pharmacists AAoP","unstructured":"Pharmacists AAoP. 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