{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T10:08:49Z","timestamp":1784196529284,"version":"3.55.0"},"reference-count":37,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T00:00:00Z","timestamp":1783900800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Jiangsu Province Young Science and Technology Talent Support Program","award":["JSTJ-2025-474"],"award-info":[{"award-number":["JSTJ-2025-474"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Australas Psychiatry"],"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This study aimed to explore the associations of pain status with long-term depressive symptoms, cognition, and the trajectories of both.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 10,683 and 4644 individuals were included in this study. The generalized estimation equation and multinomial logistic regression was applied to explore the association of pain status with long-term depressive symptoms, cognition, and the trajectories of them.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Compared to individuals without pain, those with pain were positively related to depressive symptoms (adjusted \u03b2 = 0.479, 95% CI: 0.449, 0.508), and were negatively related to cognitive function (adjusted \u03b2 = \u22120.166, 95%CI: \u22120.212, \u22120.119). Both four depressive and cognitive trajectories were identified. Participants with pain were associated with significantly increased risk of moderate-stable (Traj 2, OR = 2.78, 95% CI 2.49-3.09), extra-stable (Traj 3, OR = 6.14, 95% CI 5.36-7.03) and high-stable depressive symptoms trajectory (Traj 4, OR = 12.55, 95% CI 9.70-16.24). Participants with pain were also associated with significantly decreased risk of moderate-stable (Traj 2, OR = 0.71, 95% CI 0.50-0.99), extra-stable (Traj 3, OR = 0.52, 95% CI 0.36-0.74) and high-stable (Traj 4, OR = 0.35, 95% CI 0.22-0.55) cognition trajectory.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Individuals with pain were more likely to suffer more depressive symptoms, and were associated with lower scores for cognition function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10398562261470150","type":"journal-article","created":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T08:22:12Z","timestamp":1783930932000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal relationship between pain with long-term depressive symptoms, cognitive function and its trajectory among middle-aged and older adults in China"],"prefix":"10.1177","author":[{"given":"Xinyue","family":"Zhang","sequence":"first","affiliation":[{"name":"Jiangnan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyang","family":"Han","sequence":"additional","affiliation":[{"name":"Jiangnan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqun","family":"Li","sequence":"additional","affiliation":[{"name":"Jiangnan University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4842-4852","authenticated-orcid":false,"given":"Xiaowei","family":"Zheng","sequence":"additional","affiliation":[{"name":"Jiangnan University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,13]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00393-7"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.2.147"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/18.3.292"},{"key":"e_1_3_8_5_2","volume-title":"The national academies collection: reports funded by national institutes of health. Relieving pain in America: a blueprint for transforming prevention, care, education, and research","author":"Institute of Medicine Committee on Advancing Pain Research C, Education","year":"2011","unstructured":"Institute of Medicine Committee on Advancing Pain Research C, Education. The national academies collection: reports funded by national institutes of health. Relieving pain in America: a blueprint for transforming prevention, care, education, and research. National Academies Press (US) Copyright \u00a9 2011, National Academy of Sciences, 2011."},{"issue":"16","key":"e_1_3_8_6_2","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1001\/jama.2018.16009","article-title":"Chronic pain prevalence","volume":"320","author":"Kuehn B","year":"2018","unstructured":"Kuehn B. Chronic pain prevalence. 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