{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T05:23:18Z","timestamp":1792473798873,"version":"4.5.0"},"reference-count":15,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2000,9,1]],"date-time":"2000-09-01T00:00:00Z","timestamp":967766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2000,9]]},"abstract":"<jats:p>A 2-year-old female shorthair guinea pig was presented to the Veterinary Medical Teaching Hospital, University of Wisconsin\u2013Madison, for evaluation of a unilateral corneal opacity of 1 week duration. Physical examination revealed a markedly thickened right cornea and lymphadenopathy of the submandibular and prescapular lymph nodes. Cytology of a lymph node aspirate was highly suggestive of lymphoma. The animal was humanely euthanized. Postmortem examination revealed a disseminated lymphadenopathy involving the submandibular, anterior cervical, prescapular, bronchial, anterior mediastinal, and mesenteric nodes, and hepatomegaly with accentuation of lobular morphology. The right cornea was dark red, dry and dull, and diffusely thickened, and the globe was exophthalmic. Microscopically, pleomorphic neoplastic lymphoblasts were present in the lymph nodes, spleen, liver, lungs, heart, rhinarium, bone marrow, and kidneys. Bilateral infiltration of the eyes by neoplastic lymphoblasts was noted, which was more extensive on the right. The neoplastic cells stained immunohistochemically as T-lymphocytes using antibodies directed against CD3 antigen.<\/jats:p>","DOI":"10.1177\/104063870001200513","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T16:20:37Z","timestamp":1305217237000},"page":"459-462","source":"Crossref","is-referenced-by-count":26,"title":["Disseminated T-Cell Lymphoma in a Guinea Pig with Bilateral Ocular Involvement"],"prefix":"10.1177","volume":"12","author":[{"given":"Howard","family":"Steinberg","sequence":"first","affiliation":[{"name":"Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin\u2013Madison, 2015 Linden Drive West, Madison, WI 53706"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2000,9,1]]},"reference":[{"key":"bibr1-104063870001200513","first-page":"337","volume":"30","author":"Congdon CC","year":"1954","journal-title":"Am J Pathol"},{"key":"bibr2-104063870001200513","first-page":"654","volume-title":"Tumors in domestic animals","author":"Cordy DR","year":"1990","edition":"3"},{"key":"bibr3-104063870001200513","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1997.tb10071.x"},{"key":"bibr4-104063870001200513","first-page":"1249","volume":"35","author":"Debout C","year":"1987","journal-title":"Pathol Biol"},{"key":"bibr5-104063870001200513","first-page":"1","volume":"36","author":"Gross L","year":"1970","journal-title":"Arch Geschwulstforsch"},{"key":"bibr6-104063870001200513","first-page":"705","volume":"13","author":"Heston WE","year":"1952","journal-title":"J Natl Cancer Inst"},{"key":"bibr7-104063870001200513","first-page":"222","volume":"30","author":"Hong CC","year":"1980","journal-title":"Lab Anim Sci"},{"key":"bibr8-104063870001200513","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-730050-4.50020-X"},{"key":"bibr9-104063870001200513","doi-asserted-by":"publisher","DOI":"10.1038\/215184a0"},{"key":"bibr10-104063870001200513","first-page":"1135","volume":"51","author":"Opler SR","year":"1967","journal-title":"Am J Pathol"},{"key":"bibr11-104063870001200513","first-page":"176","volume-title":"Pathology of laboratory rodents and rabbits","author":"Percy DH","year":"1993"},{"key":"bibr12-104063870001200513","first-page":"595","volume-title":"Thomson's special veterinary pathology","author":"Render JA","year":"1995","edition":"2"},{"key":"bibr13-104063870001200513","first-page":"191","volume":"20","author":"Rogers JB","year":"1960","journal-title":"Cancer Res"},{"key":"bibr14-104063870001200513","first-page":"83","volume":"38","author":"Wolff A","year":"1988","journal-title":"Lab Anim Sci"},{"key":"bibr15-104063870001200513","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1994.tb00567.x"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870001200513","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870001200513","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:44:18Z","timestamp":1777682658000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/104063870001200513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,9]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2000,9]]}},"alternative-id":["10.1177\/104063870001200513"],"URL":"https:\/\/doi.org\/10.1177\/104063870001200513","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,9]]}}}