{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T05:29:54Z","timestamp":1790573394897,"version":"4.1.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2001,5,1]],"date-time":"2001-05-01T00:00:00Z","timestamp":988675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:p>Antemortem diagnosis of generalized ulcerative and pyogranulomatous dermatitis with numerous intralesional tachyzoites was made from skin biopsy specimens from 2 adult dogs on chronic immunosuppressive therapy. A 9-year-old Italian Greyhound was on long-term corticosteroid therapy for the treatment of a lupus-like systemic autoimmune disorder, and a 7-year-old Labrador Retriever had received several months of chemotherapy for lymphosarcoma. The tachyzoites were identified as Neospora caninum by immunoperoxidase immunohistochemistry. Both dogs were treated with clindamycin. Lesions in the Greyhound resolved; however, the Labrador Retriever was euthanized because of evidence of neuromuscular disease, despite improvement of the skin lesions. These 2 cases indicate that cutaneous neosporosis can occur in adult dogs on chronic immu-nosuppressive therapy. The disease may result from reactivation of a congenital infection and\/or a recently acquired primary infection.<\/jats:p>","DOI":"10.1177\/104063870101300312","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T16:20:37Z","timestamp":1305217237000},"page":"252-255","source":"Crossref","is-referenced-by-count":27,"title":["Cutaneous Neosporosis in Two Adult Dogs on Chronic Immunosuppressive Therapy"],"prefix":"10.1177","volume":"13","author":[{"given":"Krista M. D.","family":"la Perle","sequence":"first","affiliation":[{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, Ohio State University, 1925 Coffey Road, Columbus, OH 43210"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Del Piero","sequence":"additional","affiliation":[{"name":"Department of Pathobiology, New Bolton Center, School of Veterinary Medicine University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruthann F.","family":"Carr","sequence":"additional","affiliation":[{"name":"Beechmont Pet Hospital, 1627 Burney Lane, Cincinnati, OH 45230"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryl","family":"Harris","sequence":"additional","affiliation":[{"name":"Veterinary Internal Medicine Clinic, 931 Route 28, Milford, OH 45150"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul C.","family":"Stromberg","sequence":"additional","affiliation":[{"name":"Veterinary Diagnostics, 5747 Cleveland Avenue, Suite B, Columbus, OH 43231"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2001,5,1]]},"reference":[{"key":"bibr1-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1177\/030098588001700110"},{"key":"bibr2-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1136\/vr.139.18.439"},{"key":"bibr3-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(97)00171-9"},{"key":"bibr4-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(99)00141-1"},{"key":"bibr5-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1177\/104063879300500413"},{"key":"bibr6-104063870101300312","doi-asserted-by":"publisher","DOI":"10.2307\/3282839"},{"key":"bibr7-104063870101300312","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.2460\/javma.1988.192.09.1269","volume":"192","author":"Dubey JP","year":"1988","journal-title":"J Am Vet Med Assoc"},{"key":"bibr8-104063870101300312","doi-asserted-by":"crossref","first-page":"857","DOI":"10.2460\/javma.1990.197.07.857","volume":"197","author":"Dubey JP","year":"1990","journal-title":"J Am Vet Med Assoc"},{"key":"bibr9-104063870101300312","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.2460\/ajvr.1989.50.09.1578","volume":"50","author":"Dubey JP","year":"1989","journal-title":"Am J Vet Res"},{"key":"bibr10-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(90)90103-I"},{"key":"bibr11-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1016\/0169-4758(93)90099-2"},{"key":"bibr12-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(96)01035-7"},{"key":"bibr13-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.1995.tb00039.x"},{"key":"bibr14-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1177\/104063879100300115"},{"key":"bibr15-104063870101300312","first-page":"374","volume":"108","author":"Elenkov IJ","year":"1996","journal-title":"Proc Assoc Am Physicians"},{"key":"bibr16-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3024.1999.00223.x"},{"key":"bibr17-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1988.tb02298.x"},{"key":"bibr18-104063870101300312","first-page":"21","volume":"22","author":"Fritz D","year":"1997","journal-title":"Canine Pract"},{"key":"bibr19-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(83)90580-4"},{"key":"bibr20-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1006\/expr.1996.4110"},{"key":"bibr21-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3024.1998.00184.x"},{"key":"bibr22-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7519(98)00138-6"},{"key":"bibr23-104063870101300312","first-page":"1887","volume":"216","author":"Monti DJ","year":"2000","journal-title":"J Am Vet Med Assoc"},{"key":"bibr24-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-81491-4_10"},{"key":"bibr25-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(98)00168-X"},{"key":"bibr26-104063870101300312","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(98)00135-6"},{"key":"bibr27-104063870101300312","doi-asserted-by":"publisher","DOI":"10.5326\/15473317-31-2-174"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870101300312","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870101300312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:45:19Z","timestamp":1777682719000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/104063870101300312"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["10.1177\/104063870101300312"],"URL":"https:\/\/doi.org\/10.1177\/104063870101300312","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,5]]}}}