{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:49:40Z","timestamp":1777931380969,"version":"3.51.4"},"reference-count":3,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2001,7,1]],"date-time":"2001-07-01T00:00:00Z","timestamp":993945600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2001,7]]},"abstract":"<jats:p>Complex vertebral malformation (CVM), a familial syndrome of Holstein calves, has been reported in aborted fetuses and in prematurely born, stillborn, and neonatal calves. Affected calves have anomalies in the vertebral column, including hemivertebrae, fused and misshapen vertebrae and ribs, scoliosis, and vertebral synostosis. Concurrent low body weight, symmetrical arthrogryposis, and cardiac anomalies have been documented in affected calves. The syndrome was identified and characterized in Holstein cattle in Denmark; however, a global distribution of this genetic disorder is likely based on identification of common ancestral sires widely used for artificial insemination. This is the first documented case of CVM in a Holstein calf in the USA.<\/jats:p>","DOI":"10.1177\/104063870101300409","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T16:20:37Z","timestamp":1305217237000},"page":"333-336","source":"Crossref","is-referenced-by-count":34,"title":["Complex Vertebral Malformation in a Holstein Calf: Report of a Case in the USA"],"prefix":"10.1177","volume":"13","author":[{"suffix":"Jr.","given":"Robert B.","family":"Duncan","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin B.","family":"Carrig","sequence":"additional","affiliation":[{"name":"Department of Small Animal Clinical Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorgen S.","family":"Agerholm","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology, Department of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, Bulowsvej 17, DK-1870 Frederiksberg C, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Bendixen","sequence":"additional","affiliation":[{"name":"Danish Institute of Agricultural Sciences, Department of Animal Breeding and Genetics, DK-8830 Tjele, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,7,1]]},"reference":[{"key":"bibr1-104063870101300409","doi-asserted-by":"publisher","DOI":"10.1177\/104063870101300401"},{"key":"bibr2-104063870101300409","volume-title":"Complex vertebral malformations in Holstein calves","author":"Agerholm JS","year":"2000"},{"key":"bibr3-104063870101300409","first-page":"612","volume":"147","author":"Wouda W","year":"2000","journal-title":"Vet Rec"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870101300409","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870101300409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:45:36Z","timestamp":1777682736000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/104063870101300409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7]]},"references-count":3,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2001,7]]}},"alternative-id":["10.1177\/104063870101300409"],"URL":"https:\/\/doi.org\/10.1177\/104063870101300409","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,7]]}}}