{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T16:46:23Z","timestamp":1792428383524,"version":"4.5.0"},"reference-count":11,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2005,3,1]],"date-time":"2005-03-01T00:00:00Z","timestamp":1109635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2005,3]]},"abstract":"<jats:p>Five animals in a colony of cynomolgus monkeys ( Macaca fascicularis) died or were euthanatized because of alveolar echinococcosis, during a period of 5 years. The remainder of the colony was screened for possible infection with Echinococcus multilocularis, using serology and ultrasonography. A total of 46 animals out of a group of 55 were examined. The presence of anti-Em2 antibodies analyzed with enzyme-linked immunosorbent assay was demonstrated in 3 monkeys. In 2 of these 3 monkeys, multilocular structures compatible with metacestodal cysts in the liver were identified, using ultrasonography. The presence of alveolar echinococcosis was subsequently confirmed at postmortem examination in 1 animal. The other animals are still alive. Two other monkeys were negative in the serological examination but had cystic structures in the liver, which were identified as bile duct cysts at postmortem examination in 1 animal. The other monkey is still alive. These findings suggest that serology for antibodies against the Em2 antigen may represent a useful method in identifying animals that might be infected with E. multilocularis and are therefore at risk of developing fatal alveolar echinococcosis.<\/jats:p>","DOI":"10.1177\/104063870501700215","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T16:26:52Z","timestamp":1305217612000},"page":"183-186","source":"Crossref","is-referenced-by-count":14,"title":["Detection of\n                    <i>Echinococcus Multilocularis<\/i>\n                    Infection in a Colony of Cynomolgus Monkeys (\n                    <i>Macaca Fascicularis<\/i>\n                    ) using Serology and Ultrasonography"],"prefix":"10.1177","volume":"17","author":[{"given":"Patrick","family":"Rehmann","sequence":"first","affiliation":[{"name":"Zentrum f\u00fcr Fisch und Wildtiermedizin"},{"name":"The Institut f\u00fcr Tierpathologie"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Gr\u00f6ne","sequence":"additional","affiliation":[{"name":"The Institut f\u00fcr Tierpathologie"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Gottstein","sequence":"additional","affiliation":[{"name":"The Institut f\u00fcr Parasitologie, Universit\u00e4t Bern, Berne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"V\u00f6llm","sequence":"additional","affiliation":[{"name":"The Zoologischer Garten Basel, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinz","family":"Sager","sequence":"additional","affiliation":[{"name":"The Institut f\u00fcr Parasitologie, Universit\u00e4t Bern, Berne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Janovsky","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Fisch und Wildtiermedizin"},{"name":"The Institut f\u00fcr Tierpathologie"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca N.","family":"Bacciarini","sequence":"additional","affiliation":[{"name":"Zentrum f\u00fcr Fisch und Wildtiermedizin"},{"name":"The Institut f\u00fcr Tierpathologie"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2005,3,1]]},"reference":[{"key":"bibr1-104063870501700215","doi-asserted-by":"publisher","DOI":"10.1354\/vp.41-3-229"},{"key":"bibr2-104063870501700215","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-198805000-00005"},{"key":"bibr3-104063870501700215","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-4017(01)00424-1"},{"key":"bibr4-104063870501700215","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182000059278"},{"key":"bibr5-104063870501700215","doi-asserted-by":"publisher","DOI":"10.1159\/000333544"},{"key":"bibr6-104063870501700215","volume-title":"WHO\/OIE manual on echinococcosis in humans and animals: a public health problem of global concern","author":"Eckkert J","year":"2001","edition":"2"},{"key":"bibr7-104063870501700215","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.5.3.248"},{"key":"bibr8-104063870501700215","doi-asserted-by":"publisher","DOI":"10.1016\/0166-6851(91)90004-P"},{"key":"bibr9-104063870501700215","doi-asserted-by":"publisher","DOI":"10.3201\/eid0703.017307"},{"key":"bibr10-104063870501700215","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7216-7788-0.50012-5"},{"key":"bibr11-104063870501700215","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1999.61.566"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870501700215","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870501700215","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:10:16Z","timestamp":1777680616000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/104063870501700215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,3]]}},"alternative-id":["10.1177\/104063870501700215"],"URL":"https:\/\/doi.org\/10.1177\/104063870501700215","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,3]]}}}