{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T01:18:23Z","timestamp":1791854303737,"version":"4.3.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2009,5,1]],"date-time":"2009-05-01T00:00:00Z","timestamp":1241136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:p>\n                    Etiology and methods of immunoprophylaxis against common field cellulitis in commercial turkeys were evaluated. It was determined that intravenous administration (\u223c10\n                    <jats:sup>8<\/jats:sup>\n                    cells\/ml) of 1 of 4 isolates of Clostridium septicum from cellulitis lesions rapidly caused the classic lesions of cellulitis followed by death within 36 hr at high doses. When the supernatant alone was injected into turkey poults, signs of depression and ataxia were temporarily observed for up to 20 hr after injection, but no cellulitis lesions were detected. An enzyme-linked immunosorbent assay was developed to measure antibody levels against the isolated C. septicum. This assay was used to predict susceptibility to infection. An experimental formalin-killed bacterin\/toxoid was produced from the challenge strain of C. septicum with inactivation timed to allow toxin accumulation and \u223c10\n                    <jats:sup>8<\/jats:sup>\n                    cells\/ml. This bacterin\/toxoid given at day of hatch generated a rapid and persistent antibody response against the homologous C. septicum in the vaccinated birds at 9 weeks ( P &lt; 0.001). The ability of this experimental vaccine to protect birds in the field as well as its ability to evaluate unvaccinated flocks to establish the time of seroconversion and the relationship to clinical disease are currently under evaluation.\n                  <\/jats:p>","DOI":"10.1177\/104063870902100313","type":"journal-article","created":{"date-parts":[[2011,5,12]],"date-time":"2011-05-12T16:29:05Z","timestamp":1305217745000},"page":"374-377","source":"Crossref","is-referenced-by-count":32,"title":["Evidence for\n                    <i>Clostridium Septicum<\/i>\n                    as a Primary Cause of Cellulitis in Commercial Turkeys"],"prefix":"10.1177","volume":"21","author":[{"given":"Guillermo","family":"Tellez","sequence":"first","affiliation":[{"name":"Department of Poultry Science, University of Arkansas, Fayetteville, AR."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil R.","family":"Pumford","sequence":"additional","affiliation":[{"name":"Department of Poultry Science, University of Arkansas, Fayetteville, AR."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion J.","family":"Morgan","sequence":"additional","affiliation":[{"name":"Department of Poultry Science, University of Arkansas, Fayetteville, AR."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda D.","family":"Wolfenden","sequence":"additional","affiliation":[{"name":"Department of Poultry Science, University of Arkansas, Fayetteville, AR."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Billy M.","family":"Hargis","sequence":"additional","affiliation":[{"name":"Department of Poultry Science, University of Arkansas, Fayetteville, AR."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2009,5,1]]},"reference":[{"key":"bibr1-104063870902100313","doi-asserted-by":"publisher","DOI":"10.1093\/ps\/83.9.1535"},{"key":"bibr2-104063870902100313","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.29.12.2901-2903.1991"},{"key":"bibr3-104063870902100313","doi-asserted-by":"publisher","DOI":"10.2307\/1592289"},{"key":"bibr4-104063870902100313","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.2003.02070.x"},{"key":"bibr5-104063870902100313","doi-asserted-by":"publisher","DOI":"10.1637\/0005-2086(2002)046[0192:HABEOC]2.0.CO;2"},{"key":"bibr6-104063870902100313","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.67.69"},{"key":"bibr7-104063870902100313","doi-asserted-by":"publisher","DOI":"10.1136\/vr.145.8.228"},{"key":"bibr8-104063870902100313","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0022-5347(25)00299-X","volume":"241","author":"Roberts DW","year":"1987","journal-title":"J Pharmacol Exp Ther"},{"key":"bibr9-104063870902100313","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/12.2.286"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870902100313","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/104063870902100313","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/104063870902100313","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:13:17Z","timestamp":1777680797000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/104063870902100313"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["10.1177\/104063870902100313"],"URL":"https:\/\/doi.org\/10.1177\/104063870902100313","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}