{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:02:38Z","timestamp":1790755358242,"version":"4.1.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2011,6,7]],"date-time":"2011-06-07T00:00:00Z","timestamp":1307404800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:p>Francisella asiatica is a Gram-negative, pleomorphic, facultative intracellular, bacterial pathogen that causes acute to chronic disease in a wide variety of warm-water cultured and wild fish species. Outbreaks of francisellosis in warm water fish have been documented in Taiwan, Japan, United Kingdom, Hawaii, and Latin America (including Costa Rica) but the organism has only been reported from the United States on one occasion from hybrid striped bass in California. In 2010, the bacterium was detected from diseased tilapia by culture on cystine heart agar supplemented with hemoglobin and by utilizing an F. asiatica\u2013specific real-time polymerase chain reaction assay. The tilapia ( Oreochromis niloticus) were cultured in an indoor, closed, recirculating aquaculture facility in the Midwest of the United States. The identity of isolates recovered from diseased fish was confirmed as F. asiatica by amplification and sequence comparison of the 16S ribosomal RNA and intracellular growth locus C ( iglC) gene. Gross and microscopic examination of affected tissues revealed the presence of marked anterior renomegaly and splenomegaly with severe granulomatous disease.<\/jats:p>","DOI":"10.1177\/1040638711407058","type":"journal-article","created":{"date-parts":[[2011,6,7]],"date-time":"2011-06-07T21:58:12Z","timestamp":1307483892000},"page":"821-825","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":42,"title":["<i>Francisella asiatica<\/i>\n                    as the causative agent of piscine francisellosis in cultured tilapia (\n                    <i>Oreochromis<\/i>\n                    sp.) in the United States"],"prefix":"10.1177","volume":"23","author":[{"given":"Esteban","family":"Soto","sequence":"first","affiliation":[{"name":"Louisiana State University, Department of Pathobiological Sciences, School of Veterinary Medicine, Baton Rouge, LA (Soto, Baumgartner, Wiles, Hawke)"},{"name":"Ross University, Department of 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