{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:36:06Z","timestamp":1777930566681,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2012,10,10]],"date-time":"2012-10-10T00:00:00Z","timestamp":1349827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:p>\n                    Nocardioform actinomycetes are significant causes of placentitis and abortions in horses. In the current study, antimicrobial susceptibility patterns of 38 Amycolatopsis spp. and 22 Crossiella equi isolates, the most common nocardioform actinomycetes causing placentitis in horses, were evaluated. Antimicrobial susceptibilities of these isolates were tested by broth microdilution method in a commercial system, which was designed for Nocardia spp., fast-growing Mycobacterium spp., and other aerobic actinomycetes. The minimum inhibitory concentration required to inhibit the growth of 90% of organisms (MIC\n                    <jats:sub>90<\/jats:sub>\n                    ) of the following antibiotics tested for Amycolatopsis spp. were: 4 \u00b5g\/ml for linezolid, trimethophrim\u2013sulfametaxazole (TMP-SMX), and ciprofloxacin; 8 \u00b5g\/ml for ceftriaxone, doxycycline, and minocycline; 16 \u00b5g\/ml for amoxicillin\u2013clavulanic acid, clarithromycin, and imipenem; &gt;16 \u00b5g\/ml for tobramycin; 32 \u00b5g\/ml for amikacin and cefepime; and 128 \u00b5g\/ml for cefoxitin. The MIC\n                    <jats:sub>90<\/jats:sub>\n                    levels for C. equi were 0.25 \u00b5g\/ml for doxycycline; \u22641 \u00b5g\/ml for minocycline; 2 \u00b5g\/ml for linezolid and TMP-SMX; 4 \u00b5g\/ml for ciprofloxacin; 8 \u00b5g\/ml for amoxicillin\u2013clavulanic acid, ceftriaxone, and imipenem; 16 \u00b5g\/ml for clarithromycin; &gt;16 \u00b5g\/ml for tobramycin; 32 \u00b5g\/ml for cefepime; &gt;64 \u00b5g\/ml for amikacin; and 128 \u00b5g\/ml for cefoxitin.\n                  <\/jats:p>","DOI":"10.1177\/1040638712462377","type":"journal-article","created":{"date-parts":[[2012,10,11]],"date-time":"2012-10-11T09:04:31Z","timestamp":1349946271000},"page":"1158-1161","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Antibiotic susceptibility patterns of\n                    <i>Crossiella equi<\/i>\n                    and\n                    <i>Amycolatopsis<\/i>\n                    species causing nocardioform placentitis in horses"],"prefix":"10.1177","volume":"24","author":[{"given":"Erdal","family":"Erol","sequence":"first","affiliation":[{"name":"University of Kentucky, Veterinary Diagnostic Laboratory, Lexington, KY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil M.","family":"Williams","sequence":"additional","affiliation":[{"name":"University of Kentucky, Veterinary Diagnostic Laboratory, Lexington, KY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen F.","family":"Sells","sequence":"additional","affiliation":[{"name":"University of Kentucky, Veterinary Diagnostic Laboratory, Lexington, KY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Kennedy","sequence":"additional","affiliation":[{"name":"University of Kentucky, Veterinary Diagnostic Laboratory, Lexington, KY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen J.","family":"Locke","sequence":"additional","affiliation":[{"name":"University of Kentucky, Veterinary Diagnostic Laboratory, Lexington, KY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James M.","family":"Donahue","sequence":"additional","affiliation":[{"name":"University of Kentucky, Veterinary Diagnostic Laboratory, Lexington, KY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig N.","family":"Carter","sequence":"additional","affiliation":[{"name":"University of Kentucky, Veterinary Diagnostic Laboratory, Lexington, KY"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,10,10]]},"reference":[{"key":"bibr1-1040638712462377","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-009-9193-9"},{"key":"bibr2-1040638712462377","doi-asserted-by":"publisher","DOI":"10.1016\/j.theriogenology.2010.02.023"},{"key":"bibr3-1040638712462377","unstructured":"Clinical Laboratory Standard Institute (CLSI): 2011, Susceptibility testing of\n                      Mycobacteria, Nocardiae\n                      , and other aerobic actinomycetes; approved standard\u2014second edition. 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