{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T04:30:22Z","timestamp":1781929822202,"version":"3.54.5"},"reference-count":18,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2014,5,12]],"date-time":"2014-05-12T00:00:00Z","timestamp":1399852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p>An unusual case of osteomyelitis caused by Nocardia cyriacigeorgica infection and resulting in mandibular osteomyelitis and cellulitis (lumpy jaw) is described in a young cat. A 1-cm hard nodular mass was an incidental finding in the right mandible of a 14-month-old cat during routine physical examination. The lesion was fast growing, reaching up to 6 cm in its largest dimension over a 5-week period. A core biopsy of the affected mandible revealed foci of osteolysis, woven bone formation, and a few large clusters of filamentous bacteria surrounded by fine eosinophilic amorphous material bordered by neutrophils, plasma cells, macrophages, and occasional multinucleated giant cells. Pure cultures of acid-fast variable, Gram-positive filamentous bacteria were recovered on blood and chocolate agar plates at 48-hr postinoculation. On amplification and sequencing of the 16S ribosomal RNA and 65-kDa heat shock protein genes, the microorganisms were identified as N. cyriacigeorgica, within the actinomycetes.<\/jats:p>","DOI":"10.1177\/1040638714533117","type":"journal-article","created":{"date-parts":[[2014,5,13]],"date-time":"2014-05-13T04:55:02Z","timestamp":1399956902000},"page":"580-584","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["<i>Nocardia cyriacigeorgica<\/i>\n                    as the causative agent of mandibular osteomyelitis (lumpy jaw) in a cat"],"prefix":"10.1177","volume":"26","author":[{"given":"Esteban","family":"Soto","sequence":"first","affiliation":[{"name":"Department of Biomedical Sciences, School of Veterinary Medicine, Ross University, Basseterre, St. Kitts, West Indies"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maziel","family":"Arauz","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, School of Veterinary Medicine, Ross University, Basseterre, St. Kitts, West Indies"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christa Ann","family":"Gallagher","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, School of Veterinary Medicine, Ross University, Basseterre, St. Kitts, West Indies"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar","family":"Illanes","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences, School of Veterinary Medicine, Ross University, Basseterre, St. Kitts, West Indies"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,5,12]]},"reference":[{"key":"bibr1-1040638714533117","first-page":"203","volume-title":"Laboratory methods in histotechnology","author":"Arrington JB","year":"1994"},{"key":"bibr2-1040638714533117","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2008.04.007"},{"key":"bibr3-1040638714533117","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.19.2.259-282.2006"},{"key":"bibr4-1040638714533117","unstructured":"Clinical and Laboratory Standards Institute (CLSI): 2008, Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals; approved standards. 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