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This study investigated the utility of the Lawrence Livermore Microbial Detection Array (Lawrence Livermore National Laboratory, Livermore, California), designed to detect 8,101 species of microbes, in the evaluation of known and unknown microbes in serum, oral fluid, and tonsil from pigs experimentally coinfected with Porcine reproductive and respiratory syndrome virus (PRRSV) and Porcine circovirus-2 (PCV-2). The array easily identified PRRSV and PCV-2, but at decreased sensitivities compared to standard polymerase chain reaction detection methods. The oral fluid sample was the most informative, possessing additional signatures for several swine-associated bacteria, including Streptococcus sp., Clostridium sp., and Staphylococcus sp.<\/jats:p>","DOI":"10.1177\/1040638715578484","type":"journal-article","created":{"date-parts":[[2015,4,8]],"date-time":"2015-04-08T23:17:31Z","timestamp":1428535051000},"page":"313-325","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["Application of a pathogen microarray for the analysis of viruses and bacteria in clinical diagnostic samples from pigs"],"prefix":"10.1177","volume":"27","author":[{"given":"Crystal J.","family":"Jaing","sequence":"first","affiliation":[{"name":"Physical & Life Sciences Directorate (Jaing, Thissen, Hullinger), Computations Directorate (Gardner, McLoughlin), Lawrence Livermore National Laboratory, Livermore, CA"},{"name":"Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS (Monday, Niederwerder, Rowland)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James B.","family":"Thissen","sequence":"additional","affiliation":[{"name":"Physical & Life Sciences Directorate (Jaing, Thissen, Hullinger), Computations Directorate (Gardner, McLoughlin), Lawrence Livermore National Laboratory, Livermore, CA"},{"name":"Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS (Monday, Niederwerder, Rowland)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shea N.","family":"Gardner","sequence":"additional","affiliation":[{"name":"Physical & Life Sciences Directorate (Jaing, Thissen, Hullinger), Computations Directorate (Gardner, McLoughlin), Lawrence Livermore National Laboratory, Livermore, CA"},{"name":"Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS (Monday, Niederwerder, Rowland)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin S.","family":"McLoughlin","sequence":"additional","affiliation":[{"name":"Physical & Life Sciences Directorate (Jaing, Thissen, Hullinger), Computations Directorate (Gardner, McLoughlin), Lawrence Livermore National Laboratory, Livermore, CA"},{"name":"Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS (Monday, Niederwerder, Rowland)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pam J.","family":"Hullinger","sequence":"additional","affiliation":[{"name":"Physical & Life Sciences Directorate (Jaing, Thissen, Hullinger), Computations Directorate (Gardner, McLoughlin), Lawrence Livermore National Laboratory, Livermore, CA"},{"name":"Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS (Monday, Niederwerder, Rowland)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas A.","family":"Monday","sequence":"additional","affiliation":[{"name":"Physical & Life Sciences Directorate (Jaing, Thissen, Hullinger), Computations Directorate (Gardner, McLoughlin), Lawrence Livermore National Laboratory, Livermore, CA"},{"name":"Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS (Monday, Niederwerder, Rowland)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan C.","family":"Niederwerder","sequence":"additional","affiliation":[{"name":"Physical & Life Sciences Directorate (Jaing, Thissen, Hullinger), Computations Directorate (Gardner, McLoughlin), Lawrence Livermore National Laboratory, Livermore, CA"},{"name":"Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan, KS (Monday, Niederwerder, Rowland)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond R. 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