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Within non-affected normal skin adjacent to tumors or cysts, CK7 expression was observed in luminal cells in apocrine glands; CK14 expression was observed in the stratum basale, stratum spinosum, stratum granulosum, basal layer of outer root sheath, sebaceous glands, and myoepithelial cells of apocrine glands; vimentin expression was observed in dermal papilla and scattered non-epithelial cells within the epidermis; and Bcl-2 expression was observed in scattered non-epithelial cells in the epidermis and some apocrine glands. The pattern of expression of CK7 and CK14 in cases of adenocarcinoma of the apocrine gland of the anal sac (CK7+\/CK14\u2013) and hepatoid gland tumors (CK7\u2013\/CK14+) may prove useful for diagnostic purposes. Loss of expression of CK14 and vimentin, identifying myoepithelial cells, was observed in apocrine and ceruminous adenocarcinomas. Differences in patterns of expression of Bcl-2 were observed between infundibular keratinizing acanthomas compared to trichoepitheliomas.<\/jats:p>","DOI":"10.1177\/1040638715594115","type":"journal-article","created":{"date-parts":[[2015,7,16]],"date-time":"2015-07-16T22:40:03Z","timestamp":1437086403000},"page":"497-503","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Coordinate expression of cytokeratins 7 and 14, vimentin, and Bcl-2 in canine cutaneous epithelial tumors and cysts"],"prefix":"10.1177","volume":"27","author":[{"given":"Jason B.","family":"Pieper","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Medicine (Pieper, Campbell), University of Illinois, Urbana, IL"},{"name":"Department of Pathobiology (Stern), University of Illinois, Urbana, IL"},{"name":"Veterinary Diagnostic Laboratory (LeClerc), University of Illinois, Urbana, 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