{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T00:52:41Z","timestamp":1790556761924,"version":"4.1.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,4,13]],"date-time":"2016-04-13T00:00:00Z","timestamp":1460505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:p>Cysticercus fasciolaris, the larval form of Taenia taeniaeformis, is commonly encountered in rodents. In our study, 287 wild rats ( Rattus norvegicus) in South Korea were examined in 2010 and 2011. Of 287 rats, 97 (33.8%) were infected with C. fasciolaris. A strong positive correlation was found between the host body weight and prevalence in both sexes, regardless of the year of collection. The liver was the most common habitat of the parasite, and the lung was the most frequent ectopic region, followed by mesentery, pleura, abdominal wall, and kidney. The lesions of the affected organs were generally characterized by well-developed cysts, each containing a larva. However, the cysts within kidney and abdominal wall were poorly organized, filled with abscess, and lacked larvae. Collagen types I and III, but not type IV, played significant roles in constructing the cysts at differential stages, addressed by immunohistochemistry. During cyst wall development, both collagen types contributed equally to cyst formation at the early stage, whereas collagen type I was the major component at the late stage ( p &lt; 0.05). In early-stage cysts, distribution of collagens was interestingly differential depending on the development stage, as collagen type I was localized in the outer layer and type III was located in the inner layer. Our results suggest that an appropriate remodeling process of collagen fibers is necessary for C. fasciolaris to build the well-conditioned cysts in the target organs for survival.<\/jats:p>","DOI":"10.1177\/1040638716643129","type":"journal-article","created":{"date-parts":[[2016,4,13]],"date-time":"2016-04-13T23:09:20Z","timestamp":1460588960000},"page":"263-270","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["<i>Cysticercus fasciolaris<\/i>\n                    infection in wild rats (\n                    <i>Rattus norvegicus<\/i>\n                    ) in Korea and formation of cysts by remodeling of collagen fibers"],"prefix":"10.1177","volume":"28","author":[{"given":"Byung-Woo","family":"Lee","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Suk","family":"Jeon","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hak-Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyeon-Cheol","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Il","family":"Yoon","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Gangwon, 24341, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,4,13]]},"reference":[{"key":"bibr1-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002003"},{"key":"bibr2-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1172\/JCI24282"},{"key":"bibr3-1040638716643129","first-page":"4","volume":"1","author":"Battersby SA","year":"2002","journal-title":"J Environ Health Res"},{"key":"bibr4-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2003.07.015"},{"key":"bibr5-1040638716643129","first-page":"146","volume":"36","author":"Claveria FG","year":"2005","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"bibr6-1040638716643129","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-161-40548"},{"key":"bibr7-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(81)90026-8"},{"key":"bibr8-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1007\/BF00194608"},{"key":"bibr9-1040638716643129","unstructured":"Feachem RG, eds. Sanitation and Disease: Health Aspects of Excreta and Wastewater Management. (World Bank studies in water supply and sanitation). New York: Wiley, 1983:163\u2013470."},{"key":"bibr10-1040638716643129","first-page":"187","volume":"12","author":"Firlotte WR","year":"1948","journal-title":"Can J Comp Med Vet Sci"},{"key":"bibr11-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(02)00429-4"},{"key":"bibr12-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.24.8681"},{"key":"bibr13-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2003.08.002"},{"key":"bibr14-1040638716643129","doi-asserted-by":"publisher","DOI":"10.2307\/3272774"},{"key":"bibr15-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1007\/s004360050466"},{"key":"bibr16-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2009.06.008"},{"key":"bibr17-1040638716643129","doi-asserted-by":"publisher","DOI":"10.2307\/3274537"},{"key":"bibr18-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7407.143"},{"key":"bibr19-1040638716643129","unstructured":"Johnson MD, Gad SC. The rats. In: Gad SC, ed. Animal Models in Toxicology. 2nd ed. New York: Informa Healthcare, 2006:151\u2013153."},{"key":"bibr20-1040638716643129","doi-asserted-by":"publisher","DOI":"10.2298\/ABS1002431K"},{"key":"bibr21-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1023\/A:1006219625792"},{"key":"bibr22-1040638716643129","first-page":"355","volume":"20","author":"Rohde K","year":"1966","journal-title":"Med J Malaya"},{"key":"bibr23-1040638716643129","first-page":"55","volume":"2","author":"Seo BS","year":"1964","journal-title":"Kisaengchunghak Chapchi"},{"key":"bibr24-1040638716643129","first-page":"123","volume":"6","author":"Seo BS","year":"1968","journal-title":"Kisaengchunghak Chapchi"},{"key":"bibr25-1040638716643129","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.1995.33.3.235"},{"key":"bibr26-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-4877.2008.00071.x"},{"key":"bibr27-1040638716643129","unstructured":"Soulsby EJL, ed. Helminths, arthropods and protozoa of domesticated animals. 7th ed. London, UK: Lea & Febiger, 1982:116\u2013124."},{"key":"bibr28-1040638716643129","first-page":"37","volume":"12","author":"Watanabe F","year":"1968","journal-title":"Acta Med Nagasaki"},{"key":"bibr29-1040638716643129","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2008.11.011"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1040638716643129","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1040638716643129","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1040638716643129","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:19:39Z","timestamp":1777681179000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1040638716643129"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,13]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["10.1177\/1040638716643129"],"URL":"https:\/\/doi.org\/10.1177\/1040638716643129","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,13]]}}}