{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T03:36:27Z","timestamp":1785036987165,"version":"3.55.0"},"reference-count":23,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T00:00:00Z","timestamp":1486512000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:p>An 11-d-old Holstein bull calf was presented to the Veterinary Medical Teaching Hospital at the University of Wisconsin\u2013Madison because of a 4-d history of diarrhea and persistent low-grade fever. Initial diagnosis was enteritis caused by Cryptosporidium and rotavirus. During hospitalization, the calf became stuporous and was only responsive to noxious stimuli, with hypotonia of all 4 limbs, tail, head, and neck. A cerebrospinal fluid analysis revealed xanthochromia, with marked lymphocytic pleocytosis, which was suggestive of viral meningitis and\/or encephalitis. Aichivirus B, which belongs to the Kobuvirus genus, was tentatively identified in spinal fluid by next-generation DNA sequencing. This virus can affect a multitude of species, including humans and cattle, and has been isolated from both healthy and diarrheic individuals. However, to date, a possible connection with neurologic disease has not been described, to our knowledge.<\/jats:p>","DOI":"10.1177\/1040638716685597","type":"journal-article","created":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T06:21:22Z","timestamp":1486534882000},"page":"208-211","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Identification by next-generation sequencing of\n                    <i>Aichivirus B<\/i>\n                    in a calf with enterocolitis and neurologic signs"],"prefix":"10.1177","volume":"29","author":[{"given":"Ana S. D.","family":"Moreira","sequence":"first","affiliation":[{"name":"Departments of Medical Sciences (Moreira, Raabis, Peek), University of Wisconsin\u2013Madison, Madison, WI"},{"name":"Pathobiological Sciences (Graham, Dreyfus, Sibley, Toohey-Kurth, Goldberg), University of Wisconsin\u2013Madison, Madison, WI"},{"name":"Wisconsin Veterinary Diagnostic Laboratory (Toohey-Kurth), University of Wisconsin\u2013Madison, Madison, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah M.","family":"Raabis","sequence":"additional","affiliation":[{"name":"Departments of Medical Sciences (Moreira, Raabis, Peek), University of Wisconsin\u2013Madison, Madison, WI"},{"name":"Pathobiological Sciences (Graham, Dreyfus, Sibley, Toohey-Kurth, Goldberg), University of Wisconsin\u2013Madison, Madison, WI"},{"name":"Wisconsin Veterinary Diagnostic Laboratory (Toohey-Kurth), University of Wisconsin\u2013Madison, Madison, 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Wisconsin\u2013Madison, Madison, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel D.","family":"Sibley","sequence":"additional","affiliation":[{"name":"Departments of Medical Sciences (Moreira, Raabis, Peek), University of Wisconsin\u2013Madison, Madison, WI"},{"name":"Pathobiological Sciences (Graham, Dreyfus, Sibley, Toohey-Kurth, Goldberg), University of Wisconsin\u2013Madison, Madison, WI"},{"name":"Wisconsin Veterinary Diagnostic Laboratory (Toohey-Kurth), University of Wisconsin\u2013Madison, Madison, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Godhardt-Cooper","sequence":"additional","affiliation":[{"name":"Departments of Medical Sciences (Moreira, Raabis, Peek), University of Wisconsin\u2013Madison, Madison, WI"},{"name":"Pathobiological Sciences (Graham, Dreyfus, Sibley, Toohey-Kurth, Goldberg), University of Wisconsin\u2013Madison, Madison, WI"},{"name":"Wisconsin Veterinary Diagnostic Laboratory 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