{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:10:10Z","timestamp":1787019010914,"version":"build-2736575974"},"reference-count":32,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,2,7]],"date-time":"2018-02-07T00:00:00Z","timestamp":1517961600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2018,5]]},"abstract":"<jats:p>Feline infectious peritonitis (FIP) is one of the most important viral diseases of cats worldwide. Our study describes the neuropathology and the diagnostic features of 26 cases of FIP in domestic cats. The average age of affected individuals was 11.8 mo, and there was no sex or breed predisposition. Clinical neurologic signs were noted in 22 cases, and rabies was clinically suspected in 11 cases. Twenty cats had lesions in multiple organs, and 6 cats had lesions only in the brain. Gross neuropathologic changes occurred in 15 cases and consisted of hydrocephalus (10 cases), cerebellar herniation through the foramen magnum (6 cases), cerebral swelling with flattening of gyri (2 cases), and accumulation of fibrin within ventricles (2 cases) or leptomeninges (1 case). Histologically, 3 main distinct distributions of neuropathologic changes were observed, namely periventricular encephalitis (12 cases), rhombencephalitis (8 cases), and diffuse leptomeningitis with superficial encephalitis (6 cases). Fresh tissue samples were submitted for fluorescent antibody testing (FAT) after autopsy in 17 cases, and positive results were found in only 7 cases. Immunohistochemistry (IHC) for feline coronavirus confirmed the diagnosis in all 26 cases. IHC appears to be a more sensitive and reliable test for confirmation of FIP than is FAT.<\/jats:p>","DOI":"10.1177\/1040638718755833","type":"journal-article","created":{"date-parts":[[2018,2,7]],"date-time":"2018-02-07T08:24:29Z","timestamp":1517991869000},"page":"392-399","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":40,"title":["A retrospective study of the neuropathology and diagnosis of naturally occurring feline infectious peritonitis"],"prefix":"10.1177","volume":"30","author":[{"given":"Daniel R.","family":"Rissi","sequence":"first","affiliation":[{"name":"Department of Pathology and Athens Veterinary Diagnostic Laboratory, College of Veterinary Medicine, The University of Georgia, Athens, GA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,2,7]]},"reference":[{"key":"bibr1-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2009.05.008"},{"key":"bibr2-1040638718755833","doi-asserted-by":"publisher","DOI":"10.2460\/javma.230.2.199"},{"key":"bibr3-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2004.01.010"},{"key":"bibr4-1040638718755833","doi-asserted-by":"publisher","DOI":"10.3201\/eid1807.120143"},{"key":"bibr5-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X15574757"},{"key":"bibr6-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.1998.tb02144.x"},{"key":"bibr7-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2001.tb01572.x"},{"key":"bibr8-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1016\/S1098-612X(03)00048-2"},{"key":"bibr9-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2011.01042.x"},{"key":"bibr10-1040638718755833","first-page":"1","volume":"31","author":"Goodson T","year":"2009","journal-title":"Compend Contin Educ Vet"},{"key":"bibr11-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X16640839"},{"key":"bibr12-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvsm.2004.10.011"},{"key":"bibr13-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2003.tb02515.x"},{"key":"bibr14-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1177\/0300985814522077"},{"key":"bibr15-1040638718755833","first-page":"111","volume":"30","author":"Kline KL","year":"1994","journal-title":"J Am Animal Hosp Assoc"},{"key":"bibr16-1040638718755833","first-page":"580","volume":"14","author":"Kornegay JN","year":"1978","journal-title":"J Am Animal Hosp Assoc"},{"key":"bibr17-1040638718755833","first-page":"746","volume":"167","author":"Krum S","year":"1975","journal-title":"J Am Vet Med Assoc"},{"key":"bibr18-1040638718755833","first-page":"31","volume":"167","author":"Legendre AM","year":"1975","journal-title":"J Am Vet Med Assoc"},{"key":"bibr19-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2004.tb02632.x"},{"key":"bibr20-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1177\/1098612X15615906"},{"key":"bibr21-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.2005.tb13044.x"},{"key":"bibr22-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1135(93)90126-R"},{"key":"bibr23-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1053\/jfms.2001.0126"},{"key":"bibr24-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfms.2008.09.008"},{"key":"bibr25-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1177\/0300985813511129"},{"key":"bibr26-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1354\/vp.45-2-140"},{"key":"bibr27-1040638718755833","first-page":"103","volume":"35","author":"Rand JS","year":"1994","journal-title":"Can Vet J"},{"key":"bibr28-1040638718755833","first-page":"729","volume":"160","author":"Slauson DO","year":"1972","journal-title":"J Am Vet Med Assoc"},{"key":"bibr29-1040638718755833","doi-asserted-by":"publisher","DOI":"10.1136\/vr.129.10.209"},{"key":"bibr30-1040638718755833","first-page":"997","volume":"29","author":"Tamke PG","year":"1998","journal-title":"Can Vet J"},{"key":"bibr31-1040638718755833","doi-asserted-by":"crossref","unstructured":"Uzal FA, et al. 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