{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T18:12:08Z","timestamp":1784830328063,"version":"3.55.0"},"reference-count":29,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T00:00:00Z","timestamp":1525219200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100000621","name":"Girton College, University of Cambridge","doi-asserted-by":"publisher","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/501100000621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:p>\n                    Adiaspiromycosis is a mycotic infection caused by thermally dimorphic fungi classified as Emmonsia parva and E. crescens (formerly Chrysosporium spp.) until recently, when new classifications were proposed. We document the pathologic findings in a severe case of adiaspiromycosis, with lymph node involvement, in a wild European rabbit ( Oryctolagus cuniculus). The rabbit exhibited granulomatous pneumonia with tracheobronchial lymph node enlargement. Histopathologically, the lung was expanded by myriad, densely cellular, heterophilic and granulomatous foci, surrounding bi- to trilaminar adiaspores. Adiaspore density was considered to be similar in all lung lobes. In the left caudal lung lobe, 80 adiaspores were counted in a 50-mm\n                    <jats:sup>2<\/jats:sup>\n                    area using digital image analysis. The mean and median adiaspore diameters were 240 \u00b1 52 \u03bcm and 255 \u03bcm, respectively. Tracheobronchial lymph nodes exhibited moderate numbers of similar adiaspores. PCR amplification of DNA extracted from microdissected adiaspores failed to identify Emmonsia spp.\u2013specific DNA. These data suggest that adiaspiromycosis may result in severe granulomatous pneumonia in wild European rabbits. Although confirmation of the etiologic agent by PCR using DNA extracted from formalin-fixed tissue is not always successful, digital image analysis can be used to aid accurate assessment of adiaspore density and morphology.\n                  <\/jats:p>","DOI":"10.1177\/1040638718772631","type":"journal-article","created":{"date-parts":[[2018,5,2]],"date-time":"2018-05-02T05:08:10Z","timestamp":1525237690000},"page":"614-618","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Adiaspiromycosis in a wild European rabbit, and a review of the literature"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3331-1249","authenticated-orcid":false,"given":"Katherine","family":"Hughes","sequence":"first","affiliation":[{"name":"Department of Veterinary Medicine, University of Cambridge, Cambridge, UK (Hughes)"},{"name":"Mycology Reference Laboratory, Public Health England South West Laboratory, Bristol, UK (Borman)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew M.","family":"Borman","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine, University of Cambridge, Cambridge, UK (Hughes)"},{"name":"Mycology Reference Laboratory, Public Health England South West Laboratory, Bristol, UK (Borman)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,5,2]]},"reference":[{"key":"bibr1-1040638718772631","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2460\/javma.1971.159.01.87","volume":"159","author":"al-Doory Y","year":"1971","journal-title":"J Am Vet Med 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