{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T01:29:10Z","timestamp":1785461350526,"version":"3.56.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T00:00:00Z","timestamp":1528329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>Isolates of the Burkholderia cepacia complex (BCC) are known as plant and human pathogens. We describe herein BCC infections as the cause of subcutaneous abscesses and purulent cellulitis in 5 cats. All cats were presented with an open wound, and 4 received standard wound care and empiric antibiotic therapy. Despite treatment, clinical signs worsened in 4 cats. Isolates of the BCC were obtained from all 5 cases. Two cats were submitted for postmortem examination. Subcutaneous abscesses with draining fistulas were observed. Histopathology revealed severe, pyogranulomatous cellulitis with intralesional gram-negative bacilli. Based on susceptibility results, the other 3 cats were administered effective antibiotics and recovered without complications. The BCC was cultured from the 2% chlorhexidine surgical scrub solution used in the clinic, suggesting the source of infection for 4 of 5 cats. Given the ability to grow in antiseptic solutions, the extra steps required to culture from antiseptics, and innate multidrug resistance, the BCC poses a challenge to both detect and treat. Although the BCC causes disease almost exclusively in humans with cystic fibrosis or immunodeficiency, the bacteria should also be a differential for nosocomial infections in veterinary patients.<\/jats:p>","DOI":"10.1177\/1040638718782333","type":"journal-article","created":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T05:06:57Z","timestamp":1528348017000},"page":"763-769","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Cellulitis caused by the\n                    <i>Burkholderia cepacia<\/i>\n                    complex associated with contaminated chlorhexidine 2% scrub in five domestic cats"],"prefix":"10.1177","volume":"30","author":[{"given":"Jessica K.","family":"Wong","sequence":"first","affiliation":[{"name":"Washington Animal Disease Diagnostic Laboratory and Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA (Wong)"},{"name":"Lance Animal Hospital, Gainesville, GA (Chambers)"},{"name":"Wisconsin State Veterinary Diagnostic Laboratory, Madison, WI (Elsmo)"},{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH (Jenkins)"},{"name":"Department of Pathology (Howerth, Sakamoto), College of Veterinary Medicine, University of Georgia, Athens, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara C.","family":"Chambers","sequence":"additional","affiliation":[{"name":"Washington Animal Disease Diagnostic Laboratory and Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA (Wong)"},{"name":"Lance Animal Hospital, Gainesville, GA (Chambers)"},{"name":"Wisconsin State Veterinary Diagnostic Laboratory, Madison, WI (Elsmo)"},{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH (Jenkins)"},{"name":"Department of Pathology (Howerth, Sakamoto), College of Veterinary Medicine, University of Georgia, Athens, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth J.","family":"Elsmo","sequence":"additional","affiliation":[{"name":"Washington Animal Disease Diagnostic Laboratory and Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA (Wong)"},{"name":"Lance Animal Hospital, Gainesville, GA (Chambers)"},{"name":"Wisconsin State Veterinary Diagnostic Laboratory, Madison, WI (Elsmo)"},{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH (Jenkins)"},{"name":"Department of Pathology (Howerth, Sakamoto), College of Veterinary Medicine, University of Georgia, Athens, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany L.","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Washington Animal Disease Diagnostic Laboratory and Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA (Wong)"},{"name":"Lance Animal Hospital, Gainesville, GA (Chambers)"},{"name":"Wisconsin State Veterinary Diagnostic Laboratory, Madison, WI (Elsmo)"},{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH (Jenkins)"},{"name":"Department of Pathology (Howerth, Sakamoto), College of Veterinary Medicine, University of Georgia, Athens, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth W.","family":"Howerth","sequence":"additional","affiliation":[{"name":"Washington Animal Disease Diagnostic Laboratory and Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA (Wong)"},{"name":"Lance Animal Hospital, Gainesville, GA (Chambers)"},{"name":"Wisconsin State Veterinary Diagnostic Laboratory, Madison, WI (Elsmo)"},{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH (Jenkins)"},{"name":"Department of Pathology (Howerth, Sakamoto), College of Veterinary Medicine, University of Georgia, Athens, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Washington Animal Disease Diagnostic Laboratory and Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA (Wong)"},{"name":"Lance Animal Hospital, Gainesville, GA (Chambers)"},{"name":"Wisconsin State Veterinary Diagnostic Laboratory, Madison, WI (Elsmo)"},{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH (Jenkins)"},{"name":"Department of Pathology (Howerth, Sakamoto), College of Veterinary Medicine, University of Georgia, Athens, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaori","family":"Sakamoto","sequence":"additional","affiliation":[{"name":"Washington Animal Disease Diagnostic Laboratory and Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA (Wong)"},{"name":"Lance Animal Hospital, Gainesville, GA (Chambers)"},{"name":"Wisconsin State Veterinary Diagnostic Laboratory, Madison, WI (Elsmo)"},{"name":"Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH (Jenkins)"},{"name":"Department of Pathology (Howerth, Sakamoto), College of Veterinary Medicine, University of Georgia, Athens, GA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,6,7]]},"reference":[{"key":"bibr1-1040638718782333","first-page":"233","volume":"32","author":"Akko\u00e7 A","year":"2008","journal-title":"Turk J Vet Anim Sci"},{"key":"bibr2-1040638718782333","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12210"},{"key":"bibr3-1040638718782333","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2011.00988.x"},{"key":"bibr4-1040638718782333","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-95-1-32"},{"key":"bibr5-1040638718782333","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.39.3.990-994.2001"},{"key":"bibr6-1040638718782333","unstructured":"Clinical and Laboratory Standards Institute (CLSI). 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