{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:39:02Z","timestamp":1777930742946,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T00:00:00Z","timestamp":1549584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100011003","name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria","doi-asserted-by":"crossref","award":["PL_015 N-15156"],"award-info":[{"award-number":["PL_015 N-15156"]}],"id":[{"id":"10.13039\/501100011003","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p>We describe and illustrate lesions in an outbreak of lead arsenate poisoning in beef cattle that ingested pesticide residues stored in an abandoned building of a former orange orchard. Of 70 exposed cattle, 14 had diarrhea, paresis, ataxia, recumbency, and\/or seizures. Ten of the affected animals died after a clinical course of 12\u201318\u2009h. Pathologic findings in 3 steers included extensive necrohemorrhagic, ulcerative rumenitis, omasitis, and abomasitis; lymphocytolysis in lymphoid organs; and nephrosis. Hepatic arsenic and lead levels in cases 1\u20133 were 20, 24, and 31\u2009ppm, and 8.3, 25, and 9.4\u2009ppm, respectively. Lesions in the forestomachs and lymphoid tissues have been rarely reported in cases of lead arsenate poisoning. In southern South America, these lesions are indistinguishable from those produced by Baccharis coridifolia, a toxic plant that contains macrocyclic trichothecenes, thus these conditions should be considered in the differential diagnosis of necrotizing lesions in alimentary and lymphoid organs.<\/jats:p>","DOI":"10.1177\/1040638719831413","type":"journal-article","created":{"date-parts":[[2019,2,8]],"date-time":"2019-02-08T10:19:05Z","timestamp":1549621145000},"page":"307-310","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":10,"title":["Acute lead arsenate poisoning in beef cattle in Uruguay"],"prefix":"10.1177","volume":"31","author":[{"given":"Carlos O.","family":"Schild","sequence":"first","affiliation":[{"name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria (INIA), Plataforma de Investigaci\u00f3n en Salud Animal, Estaci\u00f3n Experimental INIA La Estanzuela, Colonia, Uruguay (Schild, Giannitti, da Silva Silveira, Caffarena, Riet-Correa)"},{"name":"Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay (Schild, Caffarena)"},{"name":"Universidade Federal de Campina Grande, Para\u00edba, Brazil (Medeiros)"},{"name":"Veterinary Population Medicine Department, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN (Giannitti)"},{"name":"California Animal Health & Food Safety Laboratory, University of California, Davis, CA (Poppenga)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8799-6848","authenticated-orcid":false,"given":"Federico","family":"Giannitti","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria (INIA), Plataforma de Investigaci\u00f3n en Salud Animal, Estaci\u00f3n Experimental INIA La Estanzuela, Colonia, Uruguay (Schild, Giannitti, da Silva Silveira, Caffarena, Riet-Correa)"},{"name":"Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay (Schild, Caffarena)"},{"name":"Universidade Federal de Campina Grande, Para\u00edba, Brazil (Medeiros)"},{"name":"Veterinary Population Medicine Department, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN (Giannitti)"},{"name":"California Animal Health & Food Safety Laboratory, University of California, Davis, CA (Poppenga)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosane M. T.","family":"Medeiros","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria (INIA), Plataforma de Investigaci\u00f3n en Salud Animal, Estaci\u00f3n Experimental INIA La Estanzuela, Colonia, Uruguay (Schild, Giannitti, da Silva Silveira, Caffarena, Riet-Correa)"},{"name":"Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay (Schild, Caffarena)"},{"name":"Universidade Federal de Campina Grande, Para\u00edba, Brazil (Medeiros)"},{"name":"Veterinary Population Medicine Department, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN (Giannitti)"},{"name":"California Animal Health & Food Safety Laboratory, University of California, Davis, CA (Poppenga)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"da Silva Silveira","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria (INIA), Plataforma de Investigaci\u00f3n en Salud Animal, Estaci\u00f3n Experimental INIA La Estanzuela, Colonia, Uruguay (Schild, Giannitti, da Silva Silveira, Caffarena, Riet-Correa)"},{"name":"Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay (Schild, Caffarena)"},{"name":"Universidade Federal de Campina Grande, Para\u00edba, Brazil (Medeiros)"},{"name":"Veterinary Population Medicine Department, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN (Giannitti)"},{"name":"California Animal Health & Food Safety Laboratory, University of California, Davis, CA (Poppenga)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rub\u00e9n D.","family":"Caffarena","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria (INIA), Plataforma de Investigaci\u00f3n en Salud Animal, Estaci\u00f3n Experimental INIA La Estanzuela, Colonia, Uruguay (Schild, Giannitti, da Silva Silveira, Caffarena, Riet-Correa)"},{"name":"Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay (Schild, Caffarena)"},{"name":"Universidade Federal de Campina Grande, Para\u00edba, Brazil (Medeiros)"},{"name":"Veterinary Population Medicine Department, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN (Giannitti)"},{"name":"California Animal Health & Food Safety Laboratory, University of California, Davis, CA (Poppenga)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert H.","family":"Poppenga","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria (INIA), Plataforma de Investigaci\u00f3n en Salud Animal, Estaci\u00f3n Experimental INIA La Estanzuela, Colonia, Uruguay (Schild, Giannitti, da Silva Silveira, Caffarena, Riet-Correa)"},{"name":"Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay (Schild, Caffarena)"},{"name":"Universidade Federal de Campina Grande, Para\u00edba, Brazil (Medeiros)"},{"name":"Veterinary Population Medicine Department, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN (Giannitti)"},{"name":"California Animal Health & Food Safety Laboratory, University of California, Davis, CA (Poppenga)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franklin","family":"Riet-Correa","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria (INIA), Plataforma de Investigaci\u00f3n en Salud Animal, Estaci\u00f3n Experimental INIA La Estanzuela, Colonia, Uruguay (Schild, Giannitti, da Silva Silveira, Caffarena, Riet-Correa)"},{"name":"Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay (Schild, Caffarena)"},{"name":"Universidade Federal de Campina Grande, Para\u00edba, Brazil (Medeiros)"},{"name":"Veterinary Population Medicine Department, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN (Giannitti)"},{"name":"California Animal Health & Food Safety Laboratory, University of California, Davis, CA (Poppenga)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,2,8]]},"reference":[{"key":"bibr1-1040638719831413","first-page":"259","volume":"33","author":"Bahri LE","year":"1991","journal-title":"Vet Hum Toxicol"},{"key":"bibr2-1040638719831413","first-page":"569","volume-title":"Toxic Plants and Other Natural Toxins","volume":"1998","author":"Barros CSL"},{"key":"bibr3-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.12124"},{"key":"bibr4-1040638719831413","first-page":"303","volume-title":"Jubb, Kennedy and Palmer\u2019s Pathology of Domestic Animals","volume":"2016","author":"Cantile C","edition":"6"},{"key":"bibr5-1040638719831413","unstructured":"Constable P, et al. Arsenic and lead toxicosis. In: Constable PD, et al. Veterinary Medicine: A Textbook of the Diseases of Cattle, Horses, Sheep, Pigs and Goats. 11th ed. St. Louis, MO: Elsevier, 2017:421\u2013424, 1202\u20131208."},{"key":"bibr6-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-736X2012001200005"},{"key":"bibr7-1040638719831413","first-page":"268","volume":"5","author":"Davey DC.","year":"1941","journal-title":"Can J Comp Med"},{"key":"bibr8-1040638719831413","first-page":"329","volume":"45","author":"Faires MC.","year":"2004","journal-title":"Can Vet J"},{"key":"bibr9-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-007-8051-1"},{"key":"bibr10-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfr184"},{"key":"bibr11-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1972.tb02271.x"},{"key":"bibr12-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1136\/vr.89.16.450"},{"key":"bibr13-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1080\/00480169.1968.33767"},{"key":"bibr14-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1177\/104063870401600512"},{"key":"bibr15-1040638719831413","first-page":"1604","volume-title":"Large Animal Internal Medicine","author":"Osweiler GD.","year":"2015","edition":"5"},{"key":"bibr16-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.79.933.391"},{"key":"bibr17-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-0813.1984.tb07158.x"},{"key":"bibr18-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.7719183"},{"key":"bibr19-1040638719831413","first-page":"317","volume":"6","author":"St John JL","year":"1940","journal-title":"J Agric Res"},{"key":"bibr20-1040638719831413","doi-asserted-by":"publisher","DOI":"10.1177\/104063870701900216"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1040638719831413","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1040638719831413","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1040638719831413","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:22:23Z","timestamp":1777681343000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1040638719831413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,8]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1177\/1040638719831413"],"URL":"https:\/\/doi.org\/10.1177\/1040638719831413","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,8]]}}}