{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:39:20Z","timestamp":1777930760690,"version":"3.51.4"},"reference-count":48,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T00:00:00Z","timestamp":1560124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>A cluster of 4 bovine abortions caused by Coxiella burnetii occurred in a dairy herd in Uruguay during a 2-mo period. Case 1 consisted of a placenta from an aborted cow; cases 2\u20134 were fetuses and their placentas. Grossly, the placenta from one aborted cow had moderate, diffuse reddening of the cotyledons and loss of translucency of the intercotyledonary areas. No gross lesions were observed in the other 3 placentas. Microscopically, 2 of 4 placentas had fibrinonecrotizing placentitis with abundant intratrophoblastic gram-negative coccobacilli. C. burnetii was identified intralesionally by immunohistochemistry (IHC) in all 4 placentas, and by PCR and DNA sequencing in 3 placentas analyzed by these techniques. One fetus had mild neutrophilic alveolitis with multinucleate syncytial cells; no gross or microscopic lesions were observed in the other 2 fetuses examined. The lungs of the 3 fetuses were negative for C. burnetii by IHC. Tests performed to investigate other possible causes of abortions in the 4 cases were negative. C. burnetii causes Q fever in humans and coxiellosis in animals. Clusters of abortions in cattle by C. burnetii have not been reported previously, to our knowledge; this bacterium has been considered an opportunistic pathogen associated only with sporadic abortion in cattle. We present herein a cluster of 4 bovine abortions caused by C. burnetii in a dairy farm during a period of 2\u2009mo and a review of the literature on C. burnetii infection in cattle.<\/jats:p>","DOI":"10.1177\/1040638719856394","type":"journal-article","created":{"date-parts":[[2019,6,10]],"date-time":"2019-06-10T06:28:53Z","timestamp":1560148133000},"page":"634-639","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Bovine abortion caused by\n                    <i>Coxiella burnetii<\/i>\n                    : report of a cluster of cases in Uruguay and review of the literature"],"prefix":"10.1177","volume":"31","author":[{"given":"Melissa","family":"Mac\u00edas-Rioseco","sequence":"first","affiliation":[{"name":"Plataforma de Investigaci\u00f3n en Salud Animal, Instituto Nacional de Investigaci\u00f3n Agropecuaria, La Estanzuela, Colonia, Uruguay (Mac\u00edas-Rioseco, Riet-Correa, Fraga, Silveira, Giannitti)"},{"name":"Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay (Mac\u00edas-Rioseco, Riet-Correa)"},{"name":"California Animal Health and Food Safety Laboratory, University of California at Davis, San Bernardino, CA (Uzal)"},{"name":"Wyoming State Veterinary Diagnostic Laboratory, University of Wyoming, Laramie, WY (Miller, Sondgeroth)"},{"name":"Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN (Giannitti)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franklin","family":"Riet-Correa","sequence":"additional","affiliation":[{"name":"Plataforma de Investigaci\u00f3n en Salud Animal, Instituto Nacional de Investigaci\u00f3n Agropecuaria, La Estanzuela, Colonia, Uruguay (Mac\u00edas-Rioseco, Riet-Correa, Fraga, Silveira, Giannitti)"},{"name":"Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay (Mac\u00edas-Rioseco, Riet-Correa)"},{"name":"California Animal Health and Food 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