{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T23:03:26Z","timestamp":1777935806267,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:p>We describe and illustrate herein a case of eosinophilic pulmonary granulomatosis (EPG) in a 16-mo-old, castrated male, Great Pyrenees crossbred dog. EPG appears to differ from eosinophilic pneumonias and eosinophilic bronchopneumopathy in dogs by the presence of nodules and masses in the lungs composed of eosinophils, macrophages, and various combinations of lymphocytes, plasma cells, neutrophils, and mast cells within fibrous tissue. Specific information from this dog was added to the information from the limited number of other dogs diagnosed with EPG reported in the veterinary literature, and the information analyzed. EPG appears to have no breed or sex predilection and tends to be a disease of younger dogs, often \u2264\u20093\u2009y of age. Antemortem imaging of nodules and masses in the lungs, combined with cytologic evidence of eosinophils in the lesions, is highly suggestive of EPG, and the diagnosis can be confirmed postmortem. Concurrent eosinophilia and basophilia can be features of EPG, but their diagnostic value requires further investigation, as does the possible causal association with Dirofilaria immitis infection.<\/jats:p>","DOI":"10.1177\/1040638720907659","type":"journal-article","created":{"date-parts":[[2020,3,17]],"date-time":"2020-03-17T07:22:36Z","timestamp":1584429756000},"page":"329-335","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Canine eosinophilic pulmonary granulomatosis: case report and literature review"],"prefix":"10.1177","volume":"32","author":[{"given":"Dawn E. E.","family":"Abbott","sequence":"first","affiliation":[{"name":"Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. Current address: Tudor Glen Veterinary Hospital, St. Albert, Alberta, Canada (Abbott)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5832-2350","authenticated-orcid":false,"given":"Andrew L.","family":"Allen","sequence":"additional","affiliation":[{"name":"Department of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada. Current address: Tudor Glen Veterinary Hospital, St. Albert, Alberta, Canada (Abbott)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,3,17]]},"reference":[{"key":"bibr1-1040638720907659","first-page":"2108","volume":"41","author":"Blair LS","year":"1980","journal-title":"Am J Vet Res"},{"key":"bibr2-1040638720907659","first-page":"311","volume":"24","author":"Calvert CA","year":"1988","journal-title":"J Am Anim Hosp Assoc"},{"key":"bibr3-1040638720907659","first-page":"526","volume":"150","author":"Carroll JM","year":"1967","journal-title":"J Am Vet Med Assoc"},{"key":"bibr4-1040638720907659","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-5318-4.00011-5"},{"key":"bibr5-1040638720907659","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2460\/ajvr.1991.53.04.517","volume":"53","author":"Clark JN","year":"1992","journal-title":"Am J Vet Res"},{"key":"bibr6-1040638720907659","first-page":"41","volume":"73","author":"Confer AW","year":"1983","journal-title":"Cornell Vet"},{"key":"bibr7-1040638720907659","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12102"},{"key":"bibr8-1040638720907659","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/j.1748-5827.2012.01308.x","volume":"54","author":"Katajavuori P","year":"2013","journal-title":"J Small Anim Pract"},{"key":"bibr9-1040638720907659","first-page":"365","volume-title":"Duncan and Prasse\u2019s Veterinary Laboratory Medicine","author":"Krimer PM","year":"2011","edition":"5"},{"key":"bibr10-1040638720907659","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-35775-3.00009-6"},{"key":"bibr11-1040638720907659","doi-asserted-by":"publisher","DOI":"10.1177\/030098587901600402"},{"key":"bibr12-1040638720907659","first-page":"593","volume":"22","author":"Neer TM","year":"1986","journal-title":"J Am Anim Hosp Assoc"},{"key":"bibr13-1040638720907659","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.2460\/ajvr.1991.52.11.1922","volume":"52","author":"Paul AJ","year":"1991","journal-title":"Am J Vet Res"},{"key":"bibr14-1040638720907659","first-page":"883","volume":"47","author":"Paul AJ","year":"1986","journal-title":"Am J Vet Res"},{"key":"bibr15-1040638720907659","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2018.11.011"},{"key":"bibr16-1040638720907659","first-page":"53","volume-title":"Fundamentals of Veterinary Clinical Pathology","author":"Stockham SL","year":"2008","edition":"2"},{"key":"bibr17-1040638720907659","doi-asserted-by":"publisher","DOI":"10.1136\/vr.118.23.631"},{"key":"bibr18-1040638720907659","first-page":"45","volume-title":"Duncan and Prasse\u2019s Veterinary Laboratory Medicine","author":"Webb JL","year":"2011","edition":"5"},{"key":"bibr19-1040638720907659","first-page":"467","volume-title":"Tumors in Domestic Animals","author":"Wilson DW","year":"2017","edition":"5"},{"key":"bibr20-1040638720907659","first-page":"432","volume-title":"Withrow & MacEwen\u2019s Small Animal Clinical Oncology","author":"Withrow SJ","year":"2013","edition":"5"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1040638720907659","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1040638720907659","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1040638720907659","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:23:18Z","timestamp":1777681398000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1040638720907659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["10.1177\/1040638720907659"],"URL":"https:\/\/doi.org\/10.1177\/1040638720907659","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3]]}}}