{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T18:46:05Z","timestamp":1790793965968,"version":"4.1.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2020,7,25]],"date-time":"2020-07-25T00:00:00Z","timestamp":1595635200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:p>An 8-y-old Labrador Retriever was presented to a small animal practice in northern Virginia with a history of recent lethargy. Physical examination findings were unremarkable. Ultrasound revealed several large hepatic masses and multiple smaller masses involving the pancreas. Cytologic findings on fine-needle aspirates of the hepatic masses included inflammation and necrosis with eosinophilic, membranous oval structures consistent with cestode infection. Histopathologic findings for biopsies of these masses included extensive necrosis, inflammation, and PAS-positive hyaline-like membranous material interpreted as metacestode cyst wall. A PCR product was generated from aspirate material using primers specific for Echinococcus multilocularis. Subsequent sequence data were 100% homologous to E. multilocularis NADH dehydrogenase subunit I gene sequences. The dog received daily oral albendazole (10\u2009mg\/kg) treatment, but its condition deteriorated, and the dog was euthanized. The dog, born in Mississippi, was brought as a puppy to Virginia with no other travel history. To our knowledge, alveolar echinococcosis has not been reported previously in a dog in the United States; E. multilocularis infection was apparently acquired in the mid-Atlantic region of the United States.<\/jats:p>","DOI":"10.1177\/1040638720943842","type":"journal-article","created":{"date-parts":[[2020,7,25]],"date-time":"2020-07-25T05:50:19Z","timestamp":1595656219000},"page":"742-746","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Alveolar echinococcosis in a dog in the eastern United States"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7159-7954","authenticated-orcid":false,"given":"Anne","family":"Zajac","sequence":"first","affiliation":[{"name":"Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA (Zajac, LeRoith); Kingdom Animal Hospital, Clear Brook, VA (Fairman); Antech Diagnostics, Fountain Valley, CA (McGee, Wells); University of Guelph, Guelph, ON, Canada (Peregrine); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Jenkins); Veterinary Imaging Associates, Ashburn, VA (St John)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Fairman","sequence":"additional","affiliation":[{"name":"Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA (Zajac, LeRoith); Kingdom Animal Hospital, Clear Brook, VA (Fairman); Antech Diagnostics, Fountain Valley, CA (McGee, Wells); University of Guelph, Guelph, ON, Canada (Peregrine); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Jenkins); Veterinary Imaging Associates, Ashburn, VA (St John)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"McGee","sequence":"additional","affiliation":[{"name":"Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA (Zajac, LeRoith); Kingdom Animal Hospital, Clear Brook, VA (Fairman); Antech Diagnostics, Fountain Valley, CA (McGee, Wells); University of Guelph, Guelph, ON, Canada (Peregrine); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Jenkins); Veterinary Imaging Associates, Ashburn, VA (St John)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bridgette","family":"Wells","sequence":"additional","affiliation":[{"name":"Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA (Zajac, LeRoith); Kingdom Animal Hospital, Clear Brook, VA (Fairman); Antech Diagnostics, Fountain Valley, CA (McGee, Wells); University of Guelph, Guelph, ON, Canada (Peregrine); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Jenkins); Veterinary Imaging Associates, Ashburn, VA (St John)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Peregrine","sequence":"additional","affiliation":[{"name":"Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA (Zajac, LeRoith); Kingdom Animal Hospital, Clear Brook, VA (Fairman); Antech Diagnostics, Fountain Valley, CA (McGee, Wells); University of Guelph, Guelph, ON, Canada (Peregrine); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Jenkins); Veterinary Imaging Associates, Ashburn, VA (St John)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA (Zajac, LeRoith); Kingdom Animal Hospital, Clear Brook, VA (Fairman); Antech Diagnostics, Fountain Valley, CA (McGee, Wells); University of Guelph, Guelph, ON, Canada (Peregrine); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Jenkins); Veterinary Imaging Associates, Ashburn, VA (St John)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"LeRoith","sequence":"additional","affiliation":[{"name":"Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA (Zajac, LeRoith); Kingdom Animal Hospital, Clear Brook, VA (Fairman); Antech Diagnostics, Fountain Valley, CA (McGee, Wells); University of Guelph, Guelph, ON, Canada (Peregrine); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Jenkins); Veterinary Imaging Associates, Ashburn, VA (St John)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bethany","family":"St John","sequence":"additional","affiliation":[{"name":"Virginia Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA (Zajac, LeRoith); Kingdom Animal Hospital, Clear Brook, VA (Fairman); Antech Diagnostics, Fountain Valley, CA (McGee, Wells); University of Guelph, Guelph, ON, Canada (Peregrine); University of Saskatchewan, Saskatoon, Saskatchewan, Canada (Jenkins); Veterinary Imaging Associates, Ashburn, VA (St John)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,7,25]]},"reference":[{"key":"bibr1-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2017.05.004"},{"key":"bibr2-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2015.07.027"},{"key":"bibr3-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1136\/vr.103470"},{"key":"bibr4-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1016\/j.fawpar.2016.08.001"},{"key":"bibr5-1040638720943842","first-page":"317","volume":"95","author":"Deplazes P","year":"2017","journal-title":"Adv Parasitol"},{"key":"bibr6-1040638720943842","volume-title":"An Atlas of Metazoan Parasites in Animal Tissues","author":"Gardner C","year":"2006"},{"key":"bibr7-1040638720943842","doi-asserted-by":"publisher","DOI":"10.7589\/2014-08-214"},{"key":"bibr8-1040638720943842","doi-asserted-by":"publisher","DOI":"10.2460\/javma.253.5.563"},{"key":"bibr9-1040638720943842","doi-asserted-by":"publisher","DOI":"10.3201\/eid2502.180299"},{"key":"bibr10-1040638720943842","doi-asserted-by":"publisher","DOI":"10.3201\/eid1806.111420"},{"key":"bibr11-1040638720943842","doi-asserted-by":"publisher","DOI":"10.7589\/0090-3558-48.3.717"},{"key":"bibr12-1040638720943842","first-page":"73","volume-title":"Parasite","volume":"21","author":"Massolo A","year":"2014"},{"key":"bibr13-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2009.07.010"},{"key":"bibr14-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1111\/vcp.12210"},{"key":"bibr15-1040638720943842","first-page":"870","volume":"53","author":"Peregrine A","year":"2012","journal-title":"Can Vet J"},{"key":"bibr16-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2004.04074.x"},{"key":"bibr17-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006712"},{"key":"bibr18-1040638720943842","first-page":"551","volume":"55","author":"Skelding A","year":"2014","journal-title":"Can Vet J"},{"key":"bibr19-1040638720943842","first-page":"66","volume":"95","author":"Thompson RCA","year":"2017","journal-title":"Adv Parasitol"},{"key":"bibr20-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182007002235"},{"key":"bibr21-1040638720943842","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2010.03.004"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1040638720943842","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1040638720943842","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1040638720943842","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:23:43Z","timestamp":1777681423000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1040638720943842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,25]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["10.1177\/1040638720943842"],"URL":"https:\/\/doi.org\/10.1177\/1040638720943842","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,25]]}}}