{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T22:56:01Z","timestamp":1793228161085,"version":"4.5.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T00:00:00Z","timestamp":1626998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Louisiana Animal Disease Diagnostic Laboratory"},{"DOI":"10.13039\/501100019831","name":"conselho nacional das funda\u00e7\u00f5es estaduais de amparo \u00e0 pesquisa","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019831","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"coordena\u00e7\u00e3o de aperfei\u00e7oamento de pessoal de n\u00edvel superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>Neurologic diseases are common in domestic cats, and infectious agents are suspected to be the primary cause in 30\u201345% of cases. Among infectious etiologies, those of bacterial origin are only sporadically characterized in the literature, with few of these reports correlating gross and histologic findings with confirmatory bacteriologic identification. Here, we describe bacterial meningitis and meningoencephalomyelitis associated with Pasteurella multocida in 3 domestic cats. Purulent exudate expanding the cerebral meninges was grossly evident in 2 of the cases. In all 3 cases, histologic changes included multifocal suppurative-to-necrosuppurative meningitis and\/or meningoencephalomyelitis of variable severity. Intralesional colonies of gram-negative, short rod-shaped to coccobacillary bacteria were evident histologically in only 1 case. P. multocida was confirmed by routine bacteriologic culture in all cases. Based on our cases, we hypothesize that the upper respiratory system serves as the main portal of entry for P. multocida, leading to invasion of the central nervous system and possible systemic hematogenous dissemination. A case series of meningoencephalomyelitis associated with P. multocida infection in cats has not been reported previously, to our knowledge. We also review briefly other causes of meningoencephalomyelitis in cats.<\/jats:p>","DOI":"10.1177\/10406387211034484","type":"journal-article","created":{"date-parts":[[2021,7,24]],"date-time":"2021-07-24T02:15:00Z","timestamp":1627092900000},"page":"1156-1162","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Meningoencephalomyelitis in domestic cats: 3 cases of\n                    <i>Pasteurella multocida<\/i>\n                    infection and literature review"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4827-4011","authenticated-orcid":false,"given":"Bianca S.","family":"de Cecco","sequence":"first","affiliation":[{"name":"Department of Veterinary Pathology, Faculty of Veterinary Medicine, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3864-5915","authenticated-orcid":false,"given":"Mariano","family":"Carossino","sequence":"additional","affiliation":[{"name":"Louisiana Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"},{"name":"Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Del Piero","sequence":"additional","affiliation":[{"name":"Louisiana Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"},{"name":"Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuko","family":"Wakamatsu","sequence":"additional","affiliation":[{"name":"Louisiana Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"},{"name":"Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"},{"name":"Current address: Department of Comparative Pathobiology, Indiana Animal Disease Diagnostic Laboratory, College of Veterinary Medicine, Purdue University, West Lafayette, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria S.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Louisiana Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie W.","family":"Fowlkes","sequence":"additional","affiliation":[{"name":"Louisiana Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"},{"name":"Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"},{"name":"current address: Department of Veterinary Medicine and Surgery, Division of Basic Sciences, MD Anderson Cancer Center, The University of Texas, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7366-4391","authenticated-orcid":false,"given":"Ingeborg M.","family":"Langohr","sequence":"additional","affiliation":[{"name":"Louisiana Animal Disease Diagnostic Laboratory, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"},{"name":"Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,7,23]]},"reference":[{"key":"bibr1-10406387211034484","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcpa.2004.01.010"},{"key":"bibr2-10406387211034484","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-7020-5317-7.00004-7"},{"key":"bibr3-10406387211034484","doi-asserted-by":"publisher","DOI":"10.1354\/vp.39-5-536"},{"key":"bibr4-10406387211034484","doi-asserted-by":"publisher","DOI":"10.1177\/0300985814564986"},{"key":"bibr5-10406387211034484","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2004.09.005"},{"key":"bibr6-10406387211034484","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2005.12.012"},{"key":"bibr7-10406387211034484","first-page":"179","volume-title":"Infectious Diseases of the Dog and Cat","author":"Greene CE","year":"2012","edition":"4"},{"key":"bibr8-10406387211034484","first-page":"325","volume-title":"Infectious Diseases of the Dog and 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