{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T14:56:57Z","timestamp":1781967417309,"version":"3.54.5"},"reference-count":14,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2021,8,12]],"date-time":"2021-08-12T00:00:00Z","timestamp":1628726400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:p>Ten of 40 cows died within 48\u2009h of gaining access to a barn in which various chemicals were stored. Some of the surviving cows exhibited drooling, muscle tremors, and agitation. Postmortem examinations of 2 cows were performed in the field, and revealed nonspecific, moderate-to-severe pulmonary congestion. Liver and rumen contents, each from a different cow, were analyzed using a qualitative, multi-residue GC-MS method validated for the detection of pesticides and other chemical analytes. Using this method, extracts from the liver and rumen content samples were compared to atrazine (neat standard) and matrix-matched, control samples fortified with atrazine. GC-MS analysis detected atrazine at 215\u2009m\/z (NIST match &gt;97%) with a retention time of ~13\u2009min in liver and rumen content samples from our case. Detection of atrazine in the samples from the cows in this herd, combined with the clinical history, indicate that atrazine toxicity was the likely cause of clinical signs and death observed in this herd.<\/jats:p>","DOI":"10.1177\/10406387211036765","type":"journal-article","created":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T01:27:26Z","timestamp":1628818046000},"page":"1163-1167","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Atrazine intoxication in cattle, confirmed by gas chromatography\u2013mass spectrometry"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2332-3852","authenticated-orcid":false,"given":"Abigail J.","family":"Props","sequence":"first","affiliation":[{"name":"Indiana Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilary J.","family":"Richards","sequence":"additional","affiliation":[{"name":"Indiana Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen B.","family":"Hooser","sequence":"additional","affiliation":[{"name":"Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA"},{"name":"Indiana Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2443-6461","authenticated-orcid":false,"given":"Grant N.","family":"Burcham","sequence":"additional","affiliation":[{"name":"Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA"},{"name":"Indiana Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN, USA"},{"name":"Heeke Animal Disease Diagnostic Laboratory, Southern Indiana Purdue Agricultural Center, Dubois, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina R.","family":"Wilson-Frank","sequence":"additional","affiliation":[{"name":"Department of Comparative Pathobiology, Purdue University, West Lafayette, IN, USA"},{"name":"Indiana Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,8,12]]},"reference":[{"key":"bibr1-10406387211036765","unstructured":"Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological profile for atrazine. U.S. Department of Health and Human Services, Public Health Service, 2003. CAS 1912-24-9. https:\/\/wwwn.cdc.gov\/TSP\/ToxProfiles\/ToxProfiles.aspx?id=338&tid=59"},{"key":"bibr2-10406387211036765","doi-asserted-by":"publisher","DOI":"10.1016\/B978-044451167-6.50029-5"},{"key":"bibr3-10406387211036765","doi-asserted-by":"publisher","DOI":"10.1016\/B978-044451167-6.50037-4"},{"key":"bibr4-10406387211036765","unstructured":"Gupta PK. Organic herbicides toxic to animals. In: Line S, ed. Merck Manual: Veterinary Manual. 11th ed. 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The toxicity of some organic herbicides to cattle, sheep, and chickens. USDA, Agricultural Research Service, 1 May 1969. 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