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Clinical signs in 5 adult pregnant ewes included drooling, bloat, tachypnea, depression, ataxia, body shaking, difficulty in rising, and recumbency. Three neonatal lambs born to some of those ewes had similar clinical signs. No significant gross abnormalities were observed on autopsy. Histologically, neuronal necrosis, axonal and dendritic swelling, and loss of Purkinje neurons were observed in the cerebellum. The observation of similar neurologic clinical signs and lesions in pregnant ewes and their neonatal lambs suggests that the toxic principle of T. esculenta crosses the placenta and reaches the fetus.<\/jats:p>","DOI":"10.1177\/10406387211041098","type":"journal-article","created":{"date-parts":[[2021,8,25]],"date-time":"2021-08-25T03:16:20Z","timestamp":1629861380000},"page":"1128-1132","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Encephalopathy caused by\n                    <i>Talisia esculenta<\/i>\n                    intoxication in pregnant ewes and their newborn lambs"],"prefix":"10.1177","volume":"33","author":[{"given":"Valdir M.","family":"Almeida","sequence":"first","affiliation":[{"name":"Veterinary Hospital, Federal University of Campina Grande, Federal Rural University of Pernambuco, Recife, Pernambuco, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Givaldo B.","family":"Silva-Filho","sequence":"additional","affiliation":[{"name":"Laboratory of Animal Diagnosis, Federal Rural University of Pernambuco, Recife, Pernambuco, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisadora A. 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