{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T22:04:18Z","timestamp":1780437858828,"version":"3.54.1"},"reference-count":21,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100023078","name":"State of North Carolina","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100023078","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Bartonella\/Vector Borne Diseases Research Fund"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>\n                    A 13-y-old, spayed female dog had regenerative anemia, lymphopenia, hypoalbuminemia, and elevated hepatic biochemical parameters. Liver biopsy revealed hepatic peliosis (hepatic sinusoidal angiectasis), frequently associated with perisinusoidal fibrosis. The dog was seroreactive to\n                    <jats:italic>Bartonella<\/jats:italic>\n                    antigens by indirect fluorescent antibody assays, and quantitative PCR from blood identified\n                    <jats:italic>Bartonella vinsonii<\/jats:italic>\n                    subsp.\n                    <jats:italic>berkhoffii<\/jats:italic>\n                    genotype II. The dog was euthanized 9\u2009mo later because of acute decompensation. Autopsy revealed icteric adipose tissues, end-stage liver, and abdominal effusion. Microscopically, there was marked mixed-cell chronic hepatitis with hepatocellular loss, nodular hepatocellular regeneration, and capillary proliferation. Retrospective molecular testing documented\n                    <jats:italic>B. koehlerae<\/jats:italic>\n                    and\n                    <jats:italic>B. rochalimae<\/jats:italic>\n                    DNA in the dog\u2019s blood at 2 or more times during liver disease progression.\n                    <jats:italic>B. koehlerae<\/jats:italic>\n                    DNA was also amplified and sequenced from the autopsy sample of liver. Our case emphasizes that\n                    <jats:italic>Bartonella<\/jats:italic>\n                    infection may be associated with hepatic peliosis and end-stage liver in dogs and expands the spectrum of\n                    <jats:italic>Bartonella<\/jats:italic>\n                    species that potentially play a role in canine hepatic diseases.\n                  <\/jats:p>","DOI":"10.1177\/10406387241310868","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T02:57:01Z","timestamp":1736305021000},"page":"358-362","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Peliosis hepatis and hepatic fibrosis in a dog infected with multiple\n                    <i>Bartonella<\/i>\n                    species"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2264-307X","authenticated-orcid":false,"given":"Cynthia","family":"Robveille","sequence":"first","affiliation":[{"name":"Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cody","family":"Atkinson","sequence":"additional","affiliation":[{"name":"Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerry","family":"Cowart","sequence":"additional","affiliation":[{"name":"Texas Veterinary Pathology, Spring Branch, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7428-0138","authenticated-orcid":false,"given":"Ricardo G.","family":"Maggi","sequence":"additional","affiliation":[{"name":"Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelesh","family":"Narurkar","sequence":"additional","affiliation":[{"name":"Deerfield Animal Hospital, San Antonio TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward B.","family":"Breitschwerdt","sequence":"additional","affiliation":[{"name":"Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00430-012-0234-5"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.37.11.3618-3626.1999"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00069-09"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2008.0246.x"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000001439"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2003.222.47"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1078\/0344-0338-00339"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.216.519"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199712253372603"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells9040929"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0227234"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.3.1171-1176.2005"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.15301"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1939-1676.2000.tb01497.x"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-2427(01)00372-5"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvc.2018.04.006"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2022.2094287"},{"key":"e_1_3_3_19_2","first-page":"572","article-title":"Generalized peliosis hepatis and cirrhosis after long-term use of oral contraceptives","volume":"83","author":"van Erpecum KJ","year":"1988","unstructured":"van Erpecum KJ, et al Generalized peliosis hepatis and cirrhosis after long-term use of oral contraceptives. 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