{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T17:08:18Z","timestamp":1788109698130,"version":"build-2803163510"},"reference-count":23,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Linnaeus Veterinary Limited"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:p>A 7-y-old male neutered crossbreed dog was presented to a veterinary referral hospital with a 9-mo history of progressive non-ambulatory tetraparesis. A magnetic resonance imaging (MRI) study revealed multiple T2-weighted hyperintense intradural nodular lesions within the cervical spinal cord and nerves that were contrast-enhancing in T1-weighted post-contrast images. Neurologic signs progressed despite steroid treatment and a second MRI revealed slight enlargement of the previously seen lesions. The dog was euthanized due to severe neurologic signs. Histopathology and immunohistochemistry (laminin, S100, SOX10) confirmed multiple spindle-cell tumors from cervical spinal nerves, consistent with schwannomas. Neoplastic cells occasionally contained a large, clear vacuole (lipoblast-like change). The clinical and pathologic presentation resembles schwannomatosis, a hereditary condition in humans.<\/jats:p>","DOI":"10.1177\/10406387251329049","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T08:00:27Z","timestamp":1746604827000},"page":"657-661","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Multiple spinal nerve sheath tumors in a dog resembling schwannomatosis in humans"],"prefix":"10.1177","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5079-8930","authenticated-orcid":false,"given":"Jun Lai","family":"Tse","sequence":"first","affiliation":[{"name":"Neurology and Neurosurgery Service, Willows Veterinary Centre and Referral Service, Solihull, West Midlands, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4304-2713","authenticated-orcid":false,"given":"Agust\u00edn","family":"Rebollada-Merino","sequence":"additional","affiliation":[{"name":"Department of Population Medicine and Diagnostic Sciences, Section of Anatomic Pathology, Animal Health Diagnostic Center, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0935-7941","authenticated-orcid":false,"given":"Mart\u00ed","family":"Pumarola","sequence":"additional","affiliation":[{"name":"Mouse and Comparative Pathology Unit, Department of Animal Medicine and Surgery, Veterinary Faculty, Universitat Aut\u00f2noma de Barcelona, Bellaterra, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6317-9237","authenticated-orcid":false,"given":"Ana Liza","family":"Ortiz","sequence":"additional","affiliation":[{"name":"School of Veterinary Medicine and Science, University of Nottingham, Loughborough, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8003-1784","authenticated-orcid":false,"given":"Cristina","family":"Toni","sequence":"additional","affiliation":[{"name":"Neurology and Neurosurgery Service, Willows Veterinary Centre and Referral Service, Solihull, West Midlands, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,7]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-019-1176-4"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyab021"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/10406387241283161"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2021.11.012"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3390\/vetsci10020170"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2005.036319"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/1066896911418203"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.63346"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13028-014-0085-8"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-022-04061-0"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/glia.10077"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000163982.78900.AD"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2012-0162"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/0300985819846872"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/03009858241231562"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gim.2022.05.007"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1627471"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.08-VP-0322-S-FL"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1080\/02688697.2020.1836323"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1354\/vp.08-VP-0327-S-FL"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.3390\/vetsci9050204"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2008.01005.x"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-8389(05)70222-0"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10406387251329049","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10406387251329049","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10406387251329049","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T00:28:56Z","timestamp":1777681736000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10406387251329049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,7]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1177\/10406387251329049"],"URL":"https:\/\/doi.org\/10.1177\/10406387251329049","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,7]]}}}