{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T21:42:46Z","timestamp":1777930966030,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Fondo para la Convergencia Estructural del Mercosur","award":["FOCEM, COF 03\/11"],"award-info":[{"award-number":["FOCEM, COF 03\/11"]}]},{"DOI":"10.13039\/501100011003","name":"Instituto Nacional de Investigaci\u00f3n Agropecuaria","doi-asserted-by":"publisher","award":["PL_27"],"award-info":[{"award-number":["PL_27"]}],"id":[{"id":"10.13039\/501100011003","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Institut Pasteur de Montevideo, Unidad Mixta Pasteur + INIA"},{"DOI":"10.13039\/100008725","name":"Agencia Nacional de Investigaci\u00f3n e Innovaci\u00f3n","doi-asserted-by":"publisher","award":["FMV_1_2019_1_155861"],"award-info":[{"award-number":["FMV_1_2019_1_155861"]}],"id":[{"id":"10.13039\/100008725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:p>\n                    In April\u2013June 2017, a cluster of 4 third-trimester abortions caused by\n                    <jats:italic toggle=\"yes\">Coxiella burnetii<\/jats:italic>\n                    was diagnosed on a dairy farm with 356 Holstein cows in Uruguay. We investigated 1) the seroprevalence of\n                    <jats:italic toggle=\"yes\">C. burnetii<\/jats:italic>\n                    in cows delivering normal calves in this herd, 2) whether non-aborting cows gave birth to seropositive and\/or PCR-positive newborn calves in the year of the abortion cluster, and 3) whether seronegative newborn calves seroconverted after ingesting colostrum replacer. In March\u2013September 2017, serum samples were collected from 133 calving cows and their calves immediately after birth and before colostrum ingestion. All 266 sera were analyzed for anti\u2013\n                    <jats:italic toggle=\"yes\">C. burnetii<\/jats:italic>\n                    IgG by ELISA. Additionally, 179 blood samples from some of these animals (82 cows, 97 calves) were PCR-tested for\n                    <jats:italic toggle=\"yes\">C. burnetii<\/jats:italic>\n                    DNA. Thirty of the 133 (22.5%) cows delivering normal calves were seropositive at parturition; 4 of 82 (4.9%) were PCR-positive. All calves tested at birth by ELISA and PCR were negative. Our results suggest that congenital infection is not an important route of\n                    <jats:italic toggle=\"yes\">C. burnetii<\/jats:italic>\n                    transmission to live-born calves in this herd. We observed that 76 of 80 (95%) seronegative newborn calves in 2021 became seropositive for anti\u2013\n                    <jats:italic toggle=\"yes\">C. burnetii<\/jats:italic>\n                    IgG at 24-h-old after drinking an imported commercial colostrum replacer, which could confound seroepidemiologic surveys in herds using colostrum replacers.\n                  <\/jats:p>","DOI":"10.1177\/10406387261426475","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T04:40:26Z","timestamp":1772512826000},"page":"446-450","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["<i>Coxiella burnetii<\/i>\n                    seroconversion in neonatal calves in an infected dairy herd attributable to ingestion of imported colostrum replacer rather than vertical transmission"],"prefix":"10.1177","volume":"38","author":[{"given":"Ana","family":"Rabaza","sequence":"first","affiliation":[{"name":"Laboratorio de Bacterias Zoon\u00f3ticas, Unidad Mixta Pasteur + INIA, Institut Pasteur de Montevideo, Montevideo, Uruguay"},{"name":"Instituto de Investigaci\u00f3n Una Salud, Prorrectorado de Investigaci\u00f3n, Universidad de la Rep\u00fablica, Montevideo, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7061-8629","authenticated-orcid":false,"given":"Mat\u00edas A.","family":"Dorsch","sequence":"additional","affiliation":[{"name":"Plataforma de Investigaci\u00f3n en Salud Animal, Instituto Nacional de Investigaci\u00f3n Agropecuaria, Estaci\u00f3n Experimental La Estanzuela, Colonia, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6843-3345","authenticated-orcid":false,"given":"Mark C.","family":"Eisler","sequence":"additional","affiliation":[{"name":"Bristol Veterinary School, University of Bristol, Langford, Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline da Silva","family":"Silveira","sequence":"additional","affiliation":[{"name":"Plataforma de Investigaci\u00f3n en Salud Animal, Instituto Nacional de Investigaci\u00f3n Agropecuaria, Estaci\u00f3n Experimental La Estanzuela, Colonia, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7139-8384","authenticated-orcid":false,"given":"Melissa","family":"Mac\u00edas-Rioseco","sequence":"additional","affiliation":[{"name":"California Animal Health and Food Safety Laboratory, Tulare branch, School of Veterinary Medicine, University of California\u2013Davis, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Virginia","family":"Ar\u00e1oz","sequence":"additional","affiliation":[{"name":"Plataforma de Investigaci\u00f3n en Salud Animal, Instituto Nacional de Investigaci\u00f3n Agropecuaria, Estaci\u00f3n Experimental La Estanzuela, Colonia, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3624-2437","authenticated-orcid":false,"given":"Anderson","family":"Saravia","sequence":"additional","affiliation":[{"name":"Plataforma de Investigaci\u00f3n en Salud Animal, Instituto Nacional de Investigaci\u00f3n Agropecuaria, Estaci\u00f3n Experimental La Estanzuela, Colonia, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dar\u00edo","family":"Caffarena","sequence":"additional","affiliation":[{"name":"Plataforma de Investigaci\u00f3n en Salud Animal, Instituto Nacional de Investigaci\u00f3n Agropecuaria, Estaci\u00f3n Experimental La Estanzuela, Colonia, Uruguay"},{"name":"Unidad Acad\u00e9mica Salud de Rumiantes, Facultad de Veterinaria, Universidad de la Rep\u00fablica, Montevideo, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camila","family":"Ferrando","sequence":"additional","affiliation":[{"name":"Sistema Lechero, Instituto Nacional de Investigaci\u00f3n Agropecuaria, Estaci\u00f3n Experimental La Estanzuela, Colonia, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Mendoza","sequence":"additional","affiliation":[{"name":"Sistema Lechero, Instituto Nacional de Investigaci\u00f3n Agropecuaria, Estaci\u00f3n Experimental La Estanzuela, Colonia, Uruguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mart\u00edn","family":"Fraga","sequence":"additional","affiliation":[{"name":"Plataforma de Investigaci\u00f3n en Salud Animal, Instituto Nacional de Investigaci\u00f3n Agropecuaria, Estaci\u00f3n Experimental La Estanzuela, Colonia, 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