{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T10:44:56Z","timestamp":1791801896864,"version":"4.3.4"},"reference-count":85,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J VET Diagn Invest"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Escherichia<\/jats:italic>\n                    is one of the most studied bacterial genera and includes several clinically significant pathogenic species. Unique strategies have evolved in members of this genus to allow their survival within different niches. Although initially the\n                    <jats:italic toggle=\"yes\">Escherichia<\/jats:italic>\n                    cryptic clades (CCs) I\u2013VIII were identified as environmental bacteria, they have been found as commensals and opportunistic pathogens in animals and humans. Notably, members of the\n                    <jats:italic toggle=\"yes\">Escherichia<\/jats:italic>\n                    CCs are commonly mistaken for\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    when using standard microbiologic techniques for species identification. We used whole-genome sequencing to correctly identify\n                    <jats:italic toggle=\"yes\">E. marmotae<\/jats:italic>\n                    \u2014a member of the\n                    <jats:italic toggle=\"yes\">Escherichia<\/jats:italic>\n                    CCs\u2014that was initially misidentified as\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    as the causative agent of a urinary tract infection (UTI) in a female dog. The isolate had phenotypic and genotypic resistance to cefalexin\u2014an antibiotic used commonly for the treatment of uncomplicated UTIs\u2014and carried a set of virulence factors also present in uropathogenic\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    , which would explain the capacity of the organism to colonize the urinary tract. As a relatively new species that is phenotypically very similar to\n                    <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                    , it is quite possible that\n                    <jats:italic toggle=\"yes\">E. marmotae<\/jats:italic>\n                    infections may be underreported or misidentified. We hope that our work alerts veterinarians to consider\n                    <jats:italic toggle=\"yes\">E. marmotae<\/jats:italic>\n                    as a possible cause of UTIs in dogs, especially because this could affect treatment decisions. Additionally, our findings broaden the current understanding of the\n                    <jats:italic toggle=\"yes\">E. marmotae<\/jats:italic>\n                    ecology and host range.\n                  <\/jats:p>","DOI":"10.1177\/10406387261461260","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T08:14:22Z","timestamp":1783498462000},"page":"1202-1211","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Characterization of\n                    <i>Escherichia marmotae<\/i>\n                    , a novel pathogen causing urinary tract infection in a dog"],"prefix":"10.1177","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7313-4319","authenticated-orcid":false,"given":"Wendy","family":"Cuevas-Espelid","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5353-2081","authenticated-orcid":false,"given":"Sonsiray","family":"\u00c1lvarez-Narv\u00e1ez","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2438-5983","authenticated-orcid":false,"given":"Susan","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, University of Georgia College of Veterinary Medicine, Athens, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,8]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.65.12.5222-5230.1997"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2025.2563018"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.micro.60.080805.142106"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-024-10096-7"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/jvim.16814"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx343"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10020292"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/mra.01007-23"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ismeco\/ycae126"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms12020322"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02412-14"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2024.107173"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00072-12"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00071-11"},{"key":"e_1_3_3_17_2","unstructured":"Clinical and Laboratory Standards Institute. Development of quality control ranges breakpoints and interpretive categories for antimicrobial agents used in veterinary medicine; approved guideline. 4th ed. CLSI 2021. CLSI document VET02."},{"key":"e_1_3_3_18_2","unstructured":"Clinical and Laboratory Standards Institute. Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals; approved guideline. 5th ed. CLSI 2018. CLSI document VET01."},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2011.00298.x"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics12010154"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.873536"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781118644843.ch48"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12275-019-8651-4"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/jtm\/taz036"},{"key":"e_1_3_3_25_2","first-page":"7","volume":"172","author":"Gaastra W","year":"2014","unstructured":"Gaastra W, et al. Escherichia fergusonii. Vet Microbiol 2014;172:7\u201312.","journal-title":"Escherichia fergusonii"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-021-07405-8"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.27809-0"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1038\/s43705-021-00017-z"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.02475-0"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0903842106"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2016.08.036"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-46831-3"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1099\/ijs.0.000228"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajhp\/zxae026"},{"key":"e_1_3_3_35_2","first-page":"100093","article-title":"Phylogeny and potential virulence of cryptic clade Escherichia coli species complex isolates derived from an arable field trial","volume":"3","author":"MacKenzie K","year":"2022","unstructured":"MacKenzie K, et al. Phylogeny and potential virulence of cryptic clade Escherichia coli species complex isolates derived from an arable field trial. Curr Res Microb Sci 2022;3:100093.","journal-title":"Curr Res Microb Sci"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2015.03.008"},{"key":"e_1_3_3_37_2","article-title":"Variants of astA gene among extra-intestinal Escherichia coli of human and avian origin","volume":"364","author":"Maluta RP","year":"2017","unstructured":"Maluta RP, et al. Variants of astA gene among extra-intestinal Escherichia coli of human and avian origin. FEMS Microbiol Lett 2017;364:fnw285.","journal-title":"FEMS Microbiol Lett"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1080\/1040-840291046687"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1128\/ecosalplus.ESP-0034-2020"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty266"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.157741"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00412-13"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00670-09"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1128\/MRA.00739-20"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2025.1664775"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(79)50095-3"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-42027-y"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimc.2020.02.027"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22189922"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.14745\/ccdr.v44i05a04"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1128\/iai.64.1.146-153.1996"},{"key":"e_1_3_3_52_2","article-title":"The enveomics collection: a toolbox for specialized analyses of microbial genomes and metagenomes","volume":"4","author":"Rodriguez-R LM","year":"2016","unstructured":"Rodriguez-R LM, Konstantinidis KT. The enveomics collection: a toolbox for specialized analyses of microbial genomes and metagenomes. PeerJ Prepr 2016;4:e1900v1.","journal-title":"PeerJ Prepr"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182412952"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1128\/jb.173.19.5964-5974.1991"},{"key":"e_1_3_3_55_2","first-page":"1","article-title":"Benefits and limitations of MALDI-TOF mass spectrometry for the identification of microorganisms","volume":"2","author":"Rychert J.","year":"2019","unstructured":"Rychert J. Benefits and limitations of MALDI-TOF mass spectrometry for the identification of microorganisms. J Infect Epidemiol 2019;2:1\u20135.","journal-title":"J Infect Epidemiol"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2023.102040"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa440"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13099-019-0290-0"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1093\/femsle\/fnad097"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10020171"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0117906"},{"key":"e_1_3_3_62_2","unstructured":"Seemann T. ABRicate: mass screening of contigs for antibiotic resistance genes. 2016. https:\/\/github.com\/tseemann\/abricate"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02035-21"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10111355"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02220-23"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.001101"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.10.5951-5961.2003"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.092152899"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1111\/avj.13127"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2298"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics13100935"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac1098"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.71.9.4985-4995.2003"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0524-x"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1135(99)00174-1"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1128\/ecosalplus.esp-0002-2015"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01262-09"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03205-z"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/263768"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms11092169"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1002\/jobm.201400901"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1128\/JB.01115-06"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1111\/jam.13352"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks261"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkx217"},{"key":"e_1_3_3_86_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-41223-0"}],"container-title":["Journal of Veterinary Diagnostic Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10406387261461260","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10406387261461260","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10406387261461260","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T09:48:34Z","timestamp":1791798514000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10406387261461260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,8]]},"references-count":85,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1177\/10406387261461260"],"URL":"https:\/\/doi.org\/10.1177\/10406387261461260","relation":{},"ISSN":["1040-6387","1943-4936"],"issn-type":[{"value":"1040-6387","type":"print"},{"value":"1943-4936","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,8]]}}}